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Research shows FGF21 hormone acts directly on brain to regulate obesity

A hormone seen as a popular target to develop weight-loss drugs works by directly targeting the brain and triggering previously unknown activity in the nervous system, UT Southwestern Medical Center obesity researchers have found.

24 Oct 2014

MIT researchers develop new way to model effects of cancer-causing genetic mutations

Sequencing the genomes of tumor cells has revealed thousands of genetic mutations linked with cancer. However, sifting through this deluge of information to figure out which of these mutations actually drive cancer growth has proven to be a tedious, time-consuming process.

24 Oct 2014

Lucideon to run Biodensol together with the University of Lyon

Lucideon is pleased to announce that, together with the University of Lyon, it has been successful in its application to run ‘Biodensol’, a 7th framework European project to provide a network for initial training in the field of dentistry.

From Lucideon 23 Oct 2014

Scientists use innovative exome sequencing strategy to identify new gene associated with ALS

Using an innovative exome sequencing strategy, a team of international scientists led by John Landers, PhD, at the University of Massachusetts Medical School has shown that TUBA4A, the gene encoding the Tubulin Alpha 4A protein, is associated with familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig's Disease.

23 Oct 2014

Afatinib active against NSCLC nervous system metastases

Heavily pretreated patients with epidermal growth factor receptor-mutated non-small-cell lung cancer and central nervous system metastases may benefit from treatment with afatinib, say German researchers.

22 Oct 2014

Six platinum cycles no better than four for advanced NSCLC

Six cycles of adjuvant platinum-based chemotherapy is no better than three or four cycles for patients with advanced non-small-cell lung cancer, meta-analysis results suggests.

22 Oct 2014

Vascular receptor autoantibodies implicated in SSc-PAH

medwireNews: Autoantibodies to endothelin receptor type A and angiotensin receptor type-1 predict the development of, and mortality from, systemic sclerosis-associated pulmonary arterial hypertension, research suggests.

22 Oct 2014

Walnuts may help prevent Alzheimer's disease, study finds

A new animal study published in the Journal of Alzheimer's Disease indicates that a diet including walnuts may have a beneficial effect in reducing the risk, delaying the onset, slowing the progression of, or preventing Alzheimer's disease.

22 Oct 2014

Crown Bioscience announces U.S. expansion with new translational oncology center

Crown Bioscience, Inc., a leading global drug discovery and development service company, has announced the opening of the Crown Bioscience US Research Center to be located at the David H. Murdock Research Institute (DHMRI), in Kannapolis, N.C. The new center, which will open in the 3rd quarter of 2014, represents significant U.S. market expansion for Crown.

21 Oct 2014

GE Healthcare’s advances in imaging quantitation may help clinicians diagnose disease earlier

GE Healthcare shares a suite of advances in imaging quantitation that may help clinicians diagnose disease earlier, deliver more personalised treatment and speed up care at the 27th annual meeting of the European Association of Nuclear Medicine (EANM), 18-22 October, in Gothenburg.

21 Oct 2014

Scientists identify potent inhibitors to combat common obesity gene

Individuals who are genetically predisposed to obesity may soon have a therapeutic solution to combat their condition. A research team led by scientists from the National University of Singapore (NUS) has identified several potent inhibitors that selectively target FTO, the common fat mass and obesity-associated gene.

21 Oct 2014

Finding could help improve treatment of hearing loss caused by noise, normal aging

Scientists have restored the hearing of mice partly deafened by noise, using advanced tools to boost the production of a key protein in their ears.

21 Oct 2014

CHLA physician discusses urological issues in children

Children's Hospital Los Angeles physician-scientist Roger E. De Filippo, MD, an associate professor of urology and director of Pediatric Urology Stem Cell Research at the Keck School of Medicine of the University of Southern California discusses how science, technology and parental care can lead to improved pediatric urological health.

21 Oct 2014

New study reveals how cancer becomes drug resistant over time

Like a colony of bacteria or species of animals, cancer cells within a tumor must evolve to survive. A dose of chemotherapy may kill hundreds of thousands of cancer cells, for example, but a single cell with a unique mutation can survive and quickly generate a new batch of drug-resistant cells, making cancer hard to combat.

21 Oct 2014

Pentagon plans 30-person team to tackle Ebola in U.S.

The defense department announced Sunday that it would create a team to assist U.S. doctors responding to new Ebola cases, while the government issued more stringent guidelines for protective garb for health care workers treating Ebola patients. In addition, The Wall Street Journal profiles a biologist who has been working since 1997 on an Ebola vaccine which has been proven to block the disease in monkeys.

20 Oct 2014

Asterias, CIRM sign NGA to begin AST-OPC1 study for complete cervical spinal cord injury

Asterias Biotherapeutics, Inc. announced today that the Company has signed a Notice of Grant Award (NGA) with the California Institute of Regenerative Medicine (CIRM), effective October 1, 2014.

20 Oct 2014

Antibiotic-resistant bacteria share resources to cause chronic infections, show studies

Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt University investigators have discovered.

20 Oct 2014

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Janssen Research & Development, LLC today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA (ibrutinib) to the U.S. Food and Drug Administration by its strategic partner Pharmacyclics, Inc.

20 Oct 2014

Researchers uncover surprising way to reduce brain damage caused by head injuries

Scientists have uncovered a surprising way to reduce the brain damage caused by head injuries - stopping the body's immune system from killing brain cells. The study, published in the open access journal Acta Neuropathologica Communications, showed that in experiments on mice, an immune-based treatment reduced the size of brain lesions.

20 Oct 2014

Researchers propose new milestones to augment National Alzheimer's Plan

The U.S. Government has initiated a major effort to prevent and effectively treat Alzheimer's disease by 2025. However, a workgroup of nearly 40 Alzheimer's researchers and scientists says the research milestones in the U.S. Government's National Plan to Address Alzheimer's Disease must be broadened in scope, increased in scale, and adequately funded in order to successfully achieve this goal.

20 Oct 2014

B Cell News and Research

Research shows FGF21 hormone acts directly on brain to regulate obesity

MIT researchers develop new way to model effects of cancer-causing genetic mutations

Lucideon to run Biodensol together with the University of Lyon

Scientists use innovative exome sequencing strategy to identify new gene associated with ALS

Afatinib active against NSCLC nervous system metastases

Six platinum cycles no better than four for advanced NSCLC

Vascular receptor autoantibodies implicated in SSc-PAH

Walnuts may help prevent Alzheimer's disease, study finds

Crown Bioscience announces U.S. expansion with new translational oncology center

GE Healthcare’s advances in imaging quantitation may help clinicians diagnose disease earlier

Scientists identify potent inhibitors to combat common obesity gene

Finding could help improve treatment of hearing loss caused by noise, normal aging

CHLA physician discusses urological issues in children

New study reveals how cancer becomes drug resistant over time

Pentagon plans 30-person team to tackle Ebola in U.S.

Asterias, CIRM sign NGA to begin AST-OPC1 study for complete cervical spinal cord injury

Antibiotic-resistant bacteria share resources to cause chronic infections, show studies

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Researchers uncover surprising way to reduce brain damage caused by head injuries

Researchers propose new milestones to augment National Alzheimer's Plan

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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