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Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the current issue of the Journal of the National Cancer Institute.

22 Sep 2005

Effects of 10 commonly prescribed second-generation antidepressants studied

Because clinical depression is so disabling and affects more than 16 percent of adults in the United States at some time in their lives, researchers have worked hard to develop more effective treatments. But how much better are the newer pharmaceuticals?

21 Sep 2005

New study details side effects of five medications that are currently used to treat people with schizophrenia

A large study funded by NIH's National Institute of Mental Health (NIMH) provides, for the first time, detailed information comparing the effectiveness and side effects of five medications - both new and older medications - that are currently used to treat people with schizophrenia.

21 Sep 2005

Digital mammography detects more cancers than screen film mammography

A landmark breast cancer screening trial shows that digital mammography detected more cancers - up to 28 percent more - than screen film mammography in women 50 and younger, premenopausal and perimenopausal women, and women with dense breasts.

21 Sep 2005

Heavy alcohol consumption can significantly increase men's risk of developing atrial fibrillation

A large-scale study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that heavy alcohol consumption - 35 or more drinks per week -- can significantly increase men's risk of developing atrial fibrillation, a dangerous type of arrhythmia and one of the leading risk factors for stroke.

20 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the September 21 issue of the Journal of the National Cancer Institute.

20 Sep 2005

Researchers identify three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis

Yale School of Medicine researchers have identified three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis (MS) patients, greatly improving potential diagnosis and treatment.

20 Sep 2005

Largest ever study of smoking in the Asia Pacific region

The largest ever study of smoking in the Asia Pacific Region, and one of the largest smoking studies ever conducted anywhere in the world, has dispelled a long-held myth that smokers in Asian populations are less susceptible than Western populations to the risks of smoking, such as coronary heart disease and stroke.

20 Sep 2005

Research could improve clinical care, help educate women on premature birth

A March of Dimes expert panel has recommended a targeted research agenda designed improve the lives of thousands of babies by preventing premature birth. The agenda has been published in the American Journal of Obstetrics and Gynecology.

20 Sep 2005

Oral contraceptives appear to reduce risk of developing multiple sclerosis

Over a three-year period, the risk of developing multiple sclerosis (MS) was reduced in women taking oral contraceptives, according to a study in the September issue of Archives of Neurology.

19 Sep 2005

Injury prevention could save Maryland at least $700 million per year

In 2003, the total estimated cost of injuries in Maryland due to lost productivity and premature mortality was $1.9 billion dollars.

19 Sep 2005

Center for Law and the Public's Health receives important global designation

The Center for Law and the Public's Health at Georgetown and Johns Hopkins Universities has been designated a World Health Organization (WHO) and Pan American Health Organization (PAHO) Collaborating Center on Public Health Law and Human Rights , making it the only academic center of its kind to receive this global status.

19 Sep 2005

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

Researchers have determined the first detailed molecular images of a piece of the spike-shaped protein that the SARS virus uses to grab host cells and initiate the first stages of infection.

19 Sep 2005

Making practical markets for vaccines

Two papers published on September 13 in PLoS Medicine raise concerns about whether world leaders are getting good advice on how best to fund the development and delivery of new vaccines.

19 Sep 2005

Manic depression linked to two chromosomal regions in the human genome

An international team of 53 researchers has offered the most convincing evidence so far linking bipolar disorder, also known as manic depression, to two chromosomal regions in the human genome. The finding gives scientists refined targets for further gene studies.

19 Sep 2005

Lowering blood sugar levels could reduce the risk of coronary heart disease

Lowering blood sugar levels could reduce the risk of coronary heart disease in both diabetics and non-diabetics, according to researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions.

19 Sep 2005

Healthcare workers may be unable or unwilling to report to work during certain disasters

In a first study of its kind, researchers at the Mailman School of Public Health assessed the ability and willingness of healthcare workers to report to work in the event of disasters involving weapons of mass destruction or virulent infectious disease outbreaks.

12 Sep 2005

Concerns over the privacy of patients could be hampering efforts to spot disease clusters

...and monitor the health effects of environmental pollution, according to researchers in the latest edition of the Journal of Biomedical Informatics.

12 Sep 2005

Is suburban life making people overweight?

Or could it be that overweight people tend to choose the suburban life?

10 Sep 2005

Afghan refugee children and young adults prone to injury

Pakistan is home to 2 million Afghan refugees who fled a communist coup and Soviet occupation in 1978. A study by researchers from the Johns Hopkins University found that Afghan refugees under the age of 29 years experience more injuries than their older counterparts and children in developed countries.

10 Sep 2005