Antibodies News and Research

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SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

New research suggests that viral mutations have a minimal effect on T cell immunity, which could explain the protection provided by vaccination against severe COVID-19, despite the significant loss of neutralizing antibodies.

10 Jan 2022

Neutralization of SARS-CoV-2 variants by three-dose mRNA vaccinated kidney transplant recipient sera

In a new study, researchers determined three-dose messenger ribonucleic acid (mRNA) vaccinated kidney transplant recipients’ (KTRs) neutralizing responses against SARS-COV-2 variants, breakthrough coronavirus disease 2019 infection rate, and transplant rejection rate.

10 Jan 2022

SARS-CoV-2 Omicron variant's infectivity, vaccine breakthrough, and antibody resistance

A recent study uses an artificial intelligence model to investigate Omicron's mutations and its infectivity, vaccine escape capability, and susceptibility to monoclonal antibodies.

10 Jan 2022

SARS-CoV-2 shown to spread through cell-to-cell transmission

A new study investigated SARS-CoV-2 cell-to-cell transmission in the context of cell-free infection and compared it to SARS-CoV.

10 Jan 2022

Declining effectiveness of the BNT162b2 vaccine in adolescents infected with COVID-19

Researchers have conducted a retrospective matched case-control study to determine the protection period conferred by the BNT162b2 vaccine on adolescents aged 12 to 16.

10 Jan 2022

SARS-CoV-2 Delta sublineage AY.4.2 shows no increase in cell entry or antibody evasion

Researchers from Germany, in their recent study published in the journal Cellular & Molecular Immunology, have evaluated the mutations in the S protein of one such SARS-CoV-2 strain, a Delta sublineage AY.4.2, which is currently expanding in the UK, and have found that it neither contains any potential for increased cell entry nor antibody escape.

10 Jan 2022

History of SARS-CoV-2 infection affects longitudinal responses to BNT162b2 vaccine

In a recently published article in the journal Cell Reports, scientists have demonstrated that individuals with or without a history of coronavirus disease 2019 (COVID-19) exhibit differential humoral and cellular immune responses 14 days after receiving mRNA-based COVID-19 vaccine developed by Pfizer/BioNTech. However, at a later time point, the responses become comparable between the two groups.

9 Jan 2022

Influenza vaccination does not affect risk of SARS-CoV-2 infection or COVID-19

A new study published in The Journal of Infectious Diseases examined if influenza vaccination altered the risk of SARS-CoV-2 infection and clinical outcomes of COVID-19. The study included health care workers (HCWs) from Denmark who were offered influenza vaccination.

9 Jan 2022

Bolstering current therapeutic antibody treatments to help fight Omicron infections

Researchers test the neutralizing action of a panel of eight therapeutic monoclonal antibodies against the SARS-CoV-2 Omicron (B.1.1.529) variant.

9 Jan 2022

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

Researchers investigate the spread and transmission ability of SARS-CoV-2 lineages B.1.619 and B.1.620 in South Korea.

9 Jan 2022

SARS‑CoV‑2 Omicron variant escapes monoclonal antibodies

Researchers determine the neutralizing activity of four mAbs against ten strains of SARS-CoV-2.

9 Jan 2022

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Researchers investigate the relationship between the SARS-CoV-2 Omicron variant and immune system based on self/nonself short constituent sequences.

9 Jan 2022

Vaccinated mothers transfer SARS-CoV-2 antibodies to their breastfed infants

Women vaccinated against COVID-19 transfer SARS-CoV-2 antibodies to their breastfed infants, potentially giving their babies passive immunity against the coronavirus, according to University of Massachusetts Amherst research.

7 Jan 2022

Scientists discover antibody that inhibits a broad range of sarbecoviruses

Scientists have discovered an antibody that may lead to more effective treatments against a wide range of sarbecoviruses, the family of viruses that includes the coronavirus SARS-CoV-2 and their variants.

7 Jan 2022

Omicron variant found to be much less sensitive to neutralizing antibodies than Delta

The Omicron variant was detected for the first time in South Africa in November 2021 and has since spread to many countries.

7 Jan 2022

Booster mRNA vaccination effective in reviving anti-SARS-CoV-2 antibody titers among the elderly

A new study found that a booster dose vaccination against COVID-19 was successful in taking binding. and neutralizing antibodies to levels higher than those observed after the initial double-dose regimen.

7 Jan 2022

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

The current study was based on merged results using the CDD’s surveillance database coupled with the Vaccine Adverse Event Reporting System (VAERS), along with reports from health departments or physicians to the CDC.

7 Jan 2022

SARS-CoV-2 Omicron variant leads to widespread escape from neutralizing antibody responses

A new study reported the neutralization of Omicron by a large panel of sera collected from convalescent early pandemic, Alpha, Beta, Gamma and Delta infected individuals, as well as among vaccinees receiving three doses of the Oxford/AstraZeneca (AZD1222) or the Pfizer BioNtech (BNT16b2) vaccines.

7 Jan 2022

Broad cross-neutralization antibodies found to be effective against SARS-CoV-2 Omicron variant

A new study aimed to explore whether there is a way to induce the production of potent neutralizing antibodies capable of neutralizing all SARS-CoV-2 variants - including Omicron.

7 Jan 2022

Scrapping many Covid testing measures is a grave mistake, says London Medical Laboratory

London Medical Laboratory warns that its testing reveals nearly one in five people still have insufficient Covid antibodies.

7 Jan 2022

Antibodies News and Research

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

Neutralization of SARS-CoV-2 variants by three-dose mRNA vaccinated kidney transplant recipient sera

SARS-CoV-2 Omicron variant's infectivity, vaccine breakthrough, and antibody resistance

SARS-CoV-2 shown to spread through cell-to-cell transmission

Declining effectiveness of the BNT162b2 vaccine in adolescents infected with COVID-19

SARS-CoV-2 Delta sublineage AY.4.2 shows no increase in cell entry or antibody evasion

History of SARS-CoV-2 infection affects longitudinal responses to BNT162b2 vaccine

Influenza vaccination does not affect risk of SARS-CoV-2 infection or COVID-19

Bolstering current therapeutic antibody treatments to help fight Omicron infections

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

SARS‑CoV‑2 Omicron variant escapes monoclonal antibodies

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Vaccinated mothers transfer SARS-CoV-2 antibodies to their breastfed infants

Scientists discover antibody that inhibits a broad range of sarbecoviruses

Omicron variant found to be much less sensitive to neutralizing antibodies than Delta

Booster mRNA vaccination effective in reviving anti-SARS-CoV-2 antibody titers among the elderly

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

SARS-CoV-2 Omicron variant leads to widespread escape from neutralizing antibody responses

Broad cross-neutralization antibodies found to be effective against SARS-CoV-2 Omicron variant

Scrapping many Covid testing measures is a grave mistake, says London Medical Laboratory

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