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Researchers to explore genomes of childhood cancers

In a project supported by Genome BC, a Vancouver pediatric pathologist at the BC Cancer Agency/University of British Columbia is leading the team that will explore the genomes of four of the most challenging childhood cancers known.

23 Feb 2011

$Prolonged use of osteoporosis drugs may increase risk of unusual fractures in women$

Prolonged use of osteoporosis drugs may increase risk of unusual fractures in women

Women who take commonly prescribed drugs for osteoporosis known as bisphosphonates for five years or more may be at higher risk of certain kinds of fractures of their thigh bone, a new study has found.

23 Feb 2011

TransPharma completes ViaDor-GLP1 agonist Phase 1b trial for treatment of type II diabetes

TransPharma Medical Ltd., a specialty pharmaceutical company focused on the development and commercialization of drug products utilizing a proprietary active transdermal drug delivery technology, announced today the successful completion of a Phase 1b trial of ViaDor-GLP1 agonist, which is being developed for the treatment of diabetes mellitus type II.

22 Feb 2011

KemPharm commences KP201 Phase 1 trial for pain

KemPharm, Inc. today announced that it has commenced a Phase 1 clinical trial in healthy volunteers with KP201, its novel abuse deterrent prodrug of hydrocodone for pain. KP201 is a new chemical entity and is the most advanced opioid-based lead candidate in KemPharm's emerging pipeline.

22 Feb 2011

Mutated cancer pathway studies identify therapeutic targets for congenital heart disease

Cross-disciplinary teams of scientists studying genetic pathways that are mutated in many forms of cancer, but which also cause certain forms of congenital heart disease - including hypertrophic cardiomyopathy, a thickening of the heart muscle that is the leading cause of sudden death in children and young adults -, have introduced these mutations into mice and successfully treated HCM in the lab.

22 Feb 2011

Tropical seaweed's antifungal chemical cues may have promising antimalarial properties for humans

A group of chemical compounds used by a species of tropical seaweed to ward off fungus attacks may have promising antimalarial properties for humans. The compounds are part of a unique chemical signaling system that seaweeds use to battle enemies - and that may provide a wealth of potential new pharmaceutical compounds.

22 Feb 2011

New research: Fluid retention may explain drugs' risk of strokes and heart attacks

New research shows that medications which have raised safety concerns over heart attack and stroke risks may not have gotten approval from the Food and Drug Administration if the cardiovascular effects of fluid retention had been better understood. Fluid retention may explain the increased risk of heart attacks and strokes of medications such as Vioxx, Bextra, and Avandia.

22 Feb 2011

U.S. House approves bill cuts for older Americans

Cuts included in the spending bill approved by the U.S. House of Representatives this past week would harm seniors by drastically slashing initiatives that help older Americans to sustain their economic independence and health.

22 Feb 2011

Amphetamine linked to development of Parkinson’s disease

New research suggests that taking prescription amphetamines may raise the risk of developing Parkinson’s disease later. But, the researchers noted that the study did not prove a cause-and-effect relationship and further investigation is warranted. The research was released Feb. 19, and is scheduled to be presented in April at the American Academy of Neurology’s annual meeting in Honolulu.

21 Feb 2011

Scientists show bacteria in polluted rivers become resistant to range of antibiotics

Many of the substances in our most common medicines are manufactured in India. Some of these factories release huge quantities of drugs to the environment. Swedish scientists now show that bacteria in polluted rivers become resistant to a range of antibiotics. International experts fear that this may contribute to the development of untreatable infectious diseases world-wide.

21 Feb 2011

Scientists present new data on role of treatment preferences in depression outcomes

This study demonstrates that patients' relative preference for medication versus psychotherapy should be considered when offering a treatment to depressed patients because receiving the preferred treatment conveys an additional and clinically relevant benefit in outcome.

21 Feb 2011

Mouse model could help develop new classes of antidepressant drugs

The most widely prescribed antidepressants - medicines such as Prozac, Lexapro and Paxil - work by blocking the serotonin transporter, a brain protein that normally clears away the mood-regulating chemical serotonin. Or so the current thinking goes.

21 Feb 2011

NCPA, NACDS explain importance of pharmacies in Medicaid program

The National Association of Chain Drug Stores and the National Community Pharmacists Association have sent a joint letter to every Governor and State Medicaid Director, explaining the importance of pharmacies in Medicaid, offering recommendations, and expressing a desire to work together to cut costs without endangering Medicaid beneficiaries' access to pharmacy prescription drug services.

21 Feb 2011

ESMO creates new Community Oncology Working Group to ensure best standards of care

Receiving a cancer diagnosis is a devastating experience. Still under the shock of the bad news, patients must make many choices including who to turn to for advice and treatment, with the possibility to choose among a comprehensive cancer center, a university hospital or a community oncology hospital.

21 Feb 2011

Scientists decode DNA of parasitic worm that causes trichinosis

Scientists have decoded the DNA of the parasitic worm that causes trichinosis, a disease linked to eating raw or undercooked pork or carnivorous wild game animals, such as bear and walrus.

20 Feb 2011

Amphetamines appear to increase risk of developing Parkinson's disease: New research

New research shows people who have used amphetamines such as benzedrine and dexedrine appear to be at an increased risk of developing Parkinson's disease, according to a study released today that will be presented at the American Academy of Neurology's 63rd Annual Meeting in Honolulu April 9 to April 16, 2011.

20 Feb 2011

Scientists use synthetic oil for dispersing pathogenic fungi to prevent malaria spread

There are over 200 million cases of malaria each year and, according to the World Health Organisation, in 2009 malaria was responsible for 781,000 deaths worldwide. Malaria is spread by mosquitoes which breed in open water and spend much of their larval stage feeding on fungi and microorganisms at the water surface.

20 Feb 2011

Watson's performance on Jeopardy! inspires 700% spike in volunteers for World Community Grid

Watson wasn't the only computer system that won this week when it competed successfully against two human champions on the Jeopardy! game show.

19 Feb 2011

Nasal spray vs. injection -- what would you prefer?

Adelaide researchers have taken a step closer to the development of a universal flu vaccine, with results of a recent study showing that a vaccine delivered by a simple nasal spray could provide protection against influenza.

19 Feb 2011

How Huntington's disease proteins move from cell to cell

One bad apple is all it takes to spoil the barrel. And one misfolded protein may be all that's necessary to corrupt other proteins, forming large aggregations linked to several incurable neurodegenerative diseases such as Huntington's, Parkinson's and Alzheimer's.

19 Feb 2011

Drugs News and Research

Researchers to explore genomes of childhood cancers

Prolonged use of osteoporosis drugs may increase risk of unusual fractures in women

TransPharma completes ViaDor-GLP1 agonist Phase 1b trial for treatment of type II diabetes

KemPharm commences KP201 Phase 1 trial for pain

Mutated cancer pathway studies identify therapeutic targets for congenital heart disease

Tropical seaweed's antifungal chemical cues may have promising antimalarial properties for humans

New research: Fluid retention may explain drugs' risk of strokes and heart attacks

U.S. House approves bill cuts for older Americans

Amphetamine linked to development of Parkinson’s disease

Scientists show bacteria in polluted rivers become resistant to range of antibiotics

Scientists present new data on role of treatment preferences in depression outcomes

Mouse model could help develop new classes of antidepressant drugs

NCPA, NACDS explain importance of pharmacies in Medicaid program

ESMO creates new Community Oncology Working Group to ensure best standards of care

Scientists decode DNA of parasitic worm that causes trichinosis

Amphetamines appear to increase risk of developing Parkinson's disease: New research

Scientists use synthetic oil for dispersing pathogenic fungi to prevent malaria spread

Watson's performance on Jeopardy! inspires 700% spike in volunteers for World Community Grid

Nasal spray vs. injection -- what would you prefer?

How Huntington's disease proteins move from cell to cell

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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