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ETH researchers take major step towards personalized cancer immunotherapy

Cells belonging to the body's own immune system can help fight tumours. For several years now, this has allowed oncologists to use medications known as checkpoint inhibitors to encourage T cells to eliminate tumor cells.

30 Mar 2019

Research reveals genomic basis of acute erythroid leukemia

Acute erythroid leukemia is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. That is changing, thanks to research led by St. Jude Children's Research Hospital that appears today in the journal Nature Genetics.

30 Mar 2019

Study provides better understanding of how cilia work and what causes oscillations

Human bodies have some built-in systems to care for themselves. The cells that line our lungs, nose, brain and reproductive system have cilia, which are tiny, hair-like structures designed to sweep out fluids, cells and microbes to stay healthy.

30 Mar 2019

Chronic kidney disease of undetermined causes could be common in tropical and subtropical rural settings

Chronic kidney disease of undetermined causes, initially reported among agricultural communities in Central America and Sri Lanka, is also present in India, particularly in Southern rural areas, and could be common in other tropical and subtropical rural settings.

30 Mar 2019

Scientists create new models of tropical eye worm for development of anti-filarial drugs

Researchers at the LSTM's Centre for Drugs and Diagnostics, and University of Buea, Cameroon have developed new models of the tropical eye worm, Loa loa for the development of new drugs against filariasis.

30 Mar 2019

Preterm babies born without a protein in blood cells have higher risk of cerebral palsy and death

Researchers at the University of Illinois at Chicago have found that some preterm babies born without haptoglobin, a protein in blood cells, have higher odds of brain bleeding, cerebral palsy and death. Their findings suggest that the absence of the protein could serve as a potential biomarker indicating a need for increased monitoring or other preventive interventions.

30 Mar 2019

Study highlights need to diversify population-level genetic data for better disease prediction

Polygenic scores can predict a person's risk for conditions like coronary artery disease, breast cancer, and type 2 diabetes (T2D) with great accuracy, even in patients who lack common warning signs. This new genome analysis tool holds promise for physicians, who may be able to intervene earlier to help prevent common disease for at-risk individuals.

30 Mar 2019

Educating doctors alone may not have a noticeable effect on prescribing rates, study shows

Purely educating doctors about the importance of prescribing certain therapies may not be enough to make a meaningful impact, according to a new Penn Medicine study.

29 Mar 2019

New Hasso Plattner Institute for Digital Health launched at Mount Sinai

The Mount Sinai Health System and the Hasso Plattner Institute today announced an affiliation that brings together industry leaders with combined expertise in health care delivery, health sciences, biomedical and digital engineering, machine learning and artificial intelligence to rapidly develop digital health products with real-time predictive and preventive capabilities that empower patients and health care providers, and improve health and health outcomes.

29 Mar 2019

Study finds two new genes in the developmental defects of canine enamel

In addition to humans, hereditary disorders of enamel development occur in dogs, greatly impacting their dental health and wellbeing. A recent study reveals canine enamel disorders similar to those found in humans, linking them with ENAM and ACP4, two genes previously described in humans.

29 Mar 2019

APS-ASPET Presidential Symposium Series spotlights advances in gut microbiome research

Leading physiology and pharmacology researchers will speak in a four-part series centered on the gut microbiome--the microbe population living in the digestive tract--and its role in wound recovery, hypertension and nervous system function.

29 Mar 2019

Scientists identify two, extremely rare genetic variants linked to Alzheimer disease

Researchers have identified two, extremely rare genetic variants linked to Alzheimer disease (AD) for the first time.

29 Mar 2019

Physical activity more critical to maintain weight loss than diet, study reveals

A new study from the University of Colorado Anschutz Health and Wellness Center (AHWC) at the CU Anschutz Medical Campus revealed physical activity does more to maintain substantial weight loss than diet.

29 Mar 2019

Pediatric Cell Atlas needed for better understanding of children’s health and illnesses

Research efforts to comprehensively map adult human cells are in progress. But in a Perspective publishing March 28 in the journal Developmental Cell, researchers argue that there is a need to map children’s cells with the same level of granularity.

29 Mar 2019

Single lineage of stem cells contributes to lifelong hippocampal neurogenesis in mice

Scientists once thought that mammals entered adulthood with all of the neurons they would ever have, but studies from the 60s found that new neurons are generated in certain parts of the adult brain and pioneering studies from the 90s helped identify their origins and function.

29 Mar 2019

Johns Hopkins surgeons perform first-ever living donor HIV-to-HIV kidney transplant

For the first time, a person living with HIV has donated a kidney to a transplant recipient also living with HIV. A multidisciplinary team from Johns Hopkins Medicine completed the living donor HIV-to-HIV kidney transplant on Mar. 25. The doctors say both the donor and the recipient are doing well.

29 Mar 2019

Breakthrough study could lead to new treatments for sickle cell disease

In a breakthrough study of sickle cell disease, biomedical engineers in the University of Minnesota College of Science and Engineering have revealed that the building blocks of the disease are much less efficient at organizing than previously thought.

29 Mar 2019

Research uncovers crucial receptor involved in response to fast-acting antidepressants

Effective treatment of clinical depression remains a major mental health issue, with roughly 30 percent of patients who do not respond to any of the available treatments.

29 Mar 2019

Nanovaccine boosts immunity in mice with gut microbiome-mediated metabolic syndrome

A new class of biomaterial developed by Cornell researchers for an infectious disease nanovaccine effectively boosted immunity in mice with metabolic disorders linked to gut bacteria - a population that shows resistance to traditional flu and polio vaccines.

29 Mar 2019

Fetal exposure to nicotine linked with SIDS and cardiac arrhythmias in newborns

Fetal exposure to tobacco smoke in utero is associated with sudden infant death syndrome (SIDS) and cardiac arrhythmias in newborns. In a novel study in rabbits, investigators provide the first evidence linking fetal exposure to nicotine to long-term alterations of the cardiac sodium current.

29 Mar 2019

Medicine News and Research

ETH researchers take major step towards personalized cancer immunotherapy

Research reveals genomic basis of acute erythroid leukemia

Study provides better understanding of how cilia work and what causes oscillations

Chronic kidney disease of undetermined causes could be common in tropical and subtropical rural settings

Scientists create new models of tropical eye worm for development of anti-filarial drugs

Preterm babies born without a protein in blood cells have higher risk of cerebral palsy and death

Study highlights need to diversify population-level genetic data for better disease prediction

Educating doctors alone may not have a noticeable effect on prescribing rates, study shows

New Hasso Plattner Institute for Digital Health launched at Mount Sinai

Study finds two new genes in the developmental defects of canine enamel

APS-ASPET Presidential Symposium Series spotlights advances in gut microbiome research

Scientists identify two, extremely rare genetic variants linked to Alzheimer disease

Physical activity more critical to maintain weight loss than diet, study reveals

Pediatric Cell Atlas needed for better understanding of children’s health and illnesses

Single lineage of stem cells contributes to lifelong hippocampal neurogenesis in mice

Johns Hopkins surgeons perform first-ever living donor HIV-to-HIV kidney transplant

Breakthrough study could lead to new treatments for sickle cell disease

Research uncovers crucial receptor involved in response to fast-acting antidepressants

Nanovaccine boosts immunity in mice with gut microbiome-mediated metabolic syndrome

Fetal exposure to nicotine linked with SIDS and cardiac arrhythmias in newborns

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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