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Study: Young survivors covered by Medicare Part D often can't afford stroke medications

Young, uninsured stroke survivors or those covered by the Medicare Part D drug benefit often can't afford medications - increasing the risk for future strokes or other cardiovascular disease-related events, according to research presented at the American Stroke Association's International Stroke Conference 2011.

14 Feb 2011

Janssen, Medivir collaborate to discover and develop drugs against dengue virus

Medivir AB, the emerging research-based specialty pharmaceutical company focused on infectious diseases, announces today that it has signed a collaboration agreement with Janssen Pharmaceutica N.V. for the discovery and development of drugs for the prophylaxis and treatment of dengue virus infection.

14 Feb 2011

New clinical trial to test surgery specifically for Type 2 diabetes

A new clinical trial at NewYork-Presbyterian Hospital/Weill Cornell Medical Center is among the first to test surgery specifically for Type 2 diabetes. The aim of the study is to understand whether surgery can control diabetes, as well or even better than the best medical treatment available today. This is the first study of its kind open to patients who are overweight or mildly obese.

14 Feb 2011

Advocates call for follow-through on decade-old pledge to remove tariffs on malaria treatments, prophylactics in Africa

"Malaria prevention advocates say many lives can be saved by removing taxes and tariffs from essential commodities used to fight the disease," VOA News reports. A decade ago, African leaders promised to remove tariffs on products used to fight malaria, but only six countries have actually done so, according to the Malaria Taxes and Tariffs Advocacy Project, which held a meeting in Geneva on Wednesday, Reuters reports.

14 Feb 2011

U.S. FDA clears QMS Everolimus Immunoassay to prevent rejection in kidney transplants

The U.S. Food and Drug Administration today announced that it has cleared a test to help manage potential organ rejection in kidney transplant patients. The test, called QMS Everolimus Immunoassay, monitors the blood level of everolimus, a drug that helps prevent rejection in kidney transplants.

14 Feb 2011

Children with ADHD may have greater risk of developing substance problems in adolescence, adulthood

Children with attention-deficit hyperactivity disorder are two to three times more likely than children without the disorder to develop serious substance abuse problems in adolescence and adulthood, according to a study by UCLA psychologists and colleagues at the University of South Carolina.

14 Feb 2011

Researchers discover mechanism for normalizing blood sugar without insulin need

Diabetes can result from either a deficiency of insulin or decreased sensitivity to insulin. Researchers at Children's Hospital Boston have discovered a mechanism for normalizing blood sugar that doesn't involve insulin and could offer a new therapeutic approach to both kinds of diabetes.

14 Feb 2011

Study: Leptin resistance may help prevent ARDS, ALI development in patients with type II diabetes

Resistance to leptin, a protein that plays a key role in regulating metabolism and appetite, may help prevent the development of acute respiratory distress syndrome and acute lung injury in individuals with type II diabetes, according to a study conducted by researchers in Chicago.

13 Feb 2011

Study finds LC damage and reduction in noradrenaline levels in brain are linked with MS

Researchers at the University of Illinois at Chicago have shown for the first time that damage to a particular area of the brain and a consequent reduction in noradrenaline are associated with multiple sclerosis.

13 Feb 2011

Scientists produce SR-3306 compound to protect brain cells from Parkinson's disease

Scientists from the Florida campus of The Scripps Research Institute have produced the first known compound to show significant effectiveness in protecting brain cells directly affected by Parkinson's disease, a progressive and fatal neurodegenerative disorder.

13 Feb 2011

Genetic map for prostate cancer

Researchers have managed to uncover the whole genetic sequence in prostate cancer. This complete map, hope researchers, will eventually lead to the development of more targeted drugs and a better understanding of which prostate cancers are likely to spread, one of the biggest challenges for physicians and patients.

13 Feb 2011

Rare heart defect reproduced in petri dish, hope for cure

U.S. researchers have created beating heart cells in the lab with the same heart defect using skin cells taken from children with a rare heart defect. This means they can now test new drugs in human cells instead of mice.

13 Feb 2011

HIV trials and tribulations

A report published online February 8 in PLoS Medicine shows that mass behaviour changes could be credited with helping to remarkably reduce the number of people infected with HIV in Zimbabwe in recent years. These changes include declines in extramarital, commercial, and casual sexual relations, as well as a decline in multiple partners. These have been triggered by increased awareness of AIDS deaths and fear of infection and to some extent by the country’s economic deterioration.

13 Feb 2011

Genes for prostate cancer mapped for the first time

A genetic blue print that uncovers many of the mutations and genetic damage that drives prostate cancer and could lead to new treatments and better diagnosis has been found. This would mean earlier detection and new breeds of drugs to reverse the damage. Also each patient could have his own “cancer chart” made so that his treatment is personalized. The study, conducted by researchers from the Broad Institute, Dana-Farber Cancer Institute and Weill Cornell Medical College, appears in the Feb. 10 issue of Nature.

13 Feb 2011

Pharmacy, engineering professors at UH combine efforts to speed development of new antibiotics

Eliminating tens of thousands of manual lab experiments, two University of Houston (UH) professors are working toward a method to cut the development time of new antibiotics. While current practices typically last for more than a decade, a computerized modeling system being developed at UH will speed up this process.

11 Feb 2011

AHRQ: $25.3 billion spent for kidney disease treatment every year

Overall, an average of 3.7 million adults in the United States were treated for kidney disease each year between 2003 and 2007, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. Kidney disease can lead to renal failure and may be caused by diabetes, high blood pressure and heart disease.

11 Feb 2011

Genetic testing for inherited blood-clotting abnormalities not routinely recommended for VTE patients

Genetic testing for inherited blood-clotting abnormalities is not routinely recommended for patients with venous thromboembolism (VTE) of unknown cause, according to a new expert panel statement in a recent issue of Genetics in Medicine, the official peer-reviewed journal of The American College of Medical Genetics (ACMG).

11 Feb 2011

FDA grants Inhibitex Fast Track Designation for INX-189 in treatment of chronic hepatitis C viral infection

Inhibitex, Inc. today reported that the U.S. Food and Drug Administration ("FDA") has designated the investigation of INX-08189, a potent guanosine nucleotide polymerase inhibitor for the treatment of chronic hepatitis C viral infection, as a Fast Track development program.

11 Feb 2011

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today the publication of collaborative research in the International Journal of Biochemistry and Cell Biology entitled, "TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P."

11 Feb 2011

RF-induced heat therapy could help treat common parasitic skin infection

Scientists are hoping that heat therapy could eventually replace a complex drug regimen as the first-line treatment of a parasitic skin infection common in tropical and subtropical regions of the world.

11 Feb 2011

Drugs News and Research

Study: Young survivors covered by Medicare Part D often can't afford stroke medications

Janssen, Medivir collaborate to discover and develop drugs against dengue virus

New clinical trial to test surgery specifically for Type 2 diabetes

Advocates call for follow-through on decade-old pledge to remove tariffs on malaria treatments, prophylactics in Africa

U.S. FDA clears QMS Everolimus Immunoassay to prevent rejection in kidney transplants

Children with ADHD may have greater risk of developing substance problems in adolescence, adulthood

Researchers discover mechanism for normalizing blood sugar without insulin need

Study: Leptin resistance may help prevent ARDS, ALI development in patients with type II diabetes

Study finds LC damage and reduction in noradrenaline levels in brain are linked with MS

Scientists produce SR-3306 compound to protect brain cells from Parkinson's disease

Genetic map for prostate cancer

Rare heart defect reproduced in petri dish, hope for cure

HIV trials and tribulations

Genes for prostate cancer mapped for the first time

Pharmacy, engineering professors at UH combine efforts to speed development of new antibiotics

AHRQ: $25.3 billion spent for kidney disease treatment every year

Genetic testing for inherited blood-clotting abnormalities not routinely recommended for VTE patients

FDA grants Inhibitex Fast Track Designation for INX-189 in treatment of chronic hepatitis C viral infection

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

RF-induced heat therapy could help treat common parasitic skin infection

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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