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Nplate reduces treatment failure and splenectomies in adults with chronic immune thrombocytopenia

Amgen Inc. today announced the publication of results from the first open-label study to compare Nplate® (romiplostim) treatment to standard of care therapies (SOC) in non-splenectomized adult patients with chronic immune thrombocytopenia (ITP). The study results, which were published today in the New England Journal of Medicine (NEJM), show that both the incidence of treatment failure and need for splenectomy were reduced among the Nplate-treated patients.

11 Nov 2010

Depression associated with molecular-level disturbance in body's 24-hour clock

Depression appears to be associated with a molecular-level disturbance in the body's 24-hour clock, new research suggests.

11 Nov 2010

BCBS of Michigan alleged to have crushed pilot physical therapy program it saw as competition

USA Today: "As health care costs soared nationally, a small Michigan firm gave Ford Motor Co. a proposal to cut its physical therapy costs. The automaker signed up for an in-state pilot program, which was so successful Ford expanded it last year to cover about 390,000 employees, retirees and their families nationwide." But court "records allege Blue Cross used its position as the state's dominant insurer to try to crush TheraMatrix as it worked to also sign up Chrysler and General Motors.

11 Nov 2010

Nutech Mediworld founder presents clinical study results of hESC therapy in patients with spinal cord injury

Dr. Geeta Shroff, founder & medical director of Nutech Mediworld, presented today the summary results of a retrospective clinical study of human embryonic stem cell (hESC) therapy in patients with chronic spinal cord injury (SCI).

11 Nov 2010

tDCS electric stimulation can improve motor function in stroke patients

A noninvasive electric stimulation technique administered to both sides of the brain can help stroke patients who have lost motor skills in their hands and arms, according to a new study led by researchers at Beth Israel Deaconess Medical Center (BIDMC).

10 Nov 2010

Researchers find text messages to HIV patients improve adherence, health outcomes in Kenya trial

Using mobile-phone text messages to remind HIV patients to take their dose of life-saving medications can give a major boost to drug adherence, according to an innovative trial in Kenya unveiled on Tuesday, Agence France-Presse reports.

10 Nov 2010

Vertex to enroll additional treatment arm in telaprevir/VX-222 Phase 2 clinical trial for HCV

Vertex Pharmaceuticals Incorporated today announced plans to enroll an additional treatment arm as part of its ongoing Phase 2 clinical trial evaluating 12-week regimens of Vertex's lead investigational hepatitis C virus (HCV) protease inhibitor, telaprevir, in combination with its lead investigational HCV polymerase inhibitor, VX-222.

10 Nov 2010

New stem cell gene, enzyme replacement treatment for Tay-Sachs disease

StemCellRegenMed, Inc. announces that a new stem cell gene and enzyme replacement treatment has been performed on a fourteen month old child with Tay-Sachs disease on November 2, 2010. Tay-Sachs is a devastating disease that afflicts children primarily of parents of Jewish heritage and in very rare cases families of Eastern European background and the Cajun region in the U.S.A.

10 Nov 2010

Amarin reports $31.4 million cash balance for third quarter 2010

Amarin Corporation plc, a clinical-stage biopharmaceutical company focused on cardiovascular disease, today reported its financial and operational results for the three-month period ended September 30, 2010.

10 Nov 2010

Statins benefit ‘at risk’ patients but are underused: Study

A look at some of the large clinical trials and studies has shown that thousands of deaths could be prevented a year if people at risk of heart attack or stroke are prescribed high doses of statins. The review involves data from 170,000 patients in 26 randomized trials. The paper is published in the journal The Lancet.

10 Nov 2010

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Using proton pump inhibitors and antiplatelet drugs (thienopyridines) together is an appropriate way of treating patients with cardiovascular disease who are at high risk of upper gastrointestinal bleeds, despite recent concerns about an adverse interaction between these two types of drugs, according to an Expert Consensus Document released jointly today by the American College of Cardiology Foundation, the American College of Gastroenterology, and the American Heart Association.

10 Nov 2010

Zalicus third quarter total revenue decreases to $1.2 million

"We made solid product development progress this quarter," commented Mark H.N. Corrigan, MD, President and CEO of Zalicus. "We finalized our development plans for Synavive, and also related to Synavive, we were awarded a Therapeutic Discovery Project grant to help fund Synavive development going forward.

10 Nov 2010

Hormones and stress are major contributors to depression in women who undergo IVF

Between 20 and 30 percent of women who undergo in vitro fertilization (IVF) procedures suffer from significant symptoms of depression. Many practitioners believe that the hormone therapy involved in IVF procedures is primarily responsible for this. But new research from Tel Aviv University shows that, while this is true, other factors are even more influential.

10 Nov 2010

Researchers identify molecular cascade that drives process of reconnection in adult brain after stroke

A stroke wreaks havoc in the brain, destroying its cells and the connections between them. Depending on its severity and location, a stroke can impact someone's life forever, affecting motor activity, speech, memories, and more.

10 Nov 2010

Receptive music therapy associated with reduced depressive symptoms

A Swedish study that appears in the current issue of Psychotherapy and Psychosomatics applies music therapy to the treatment of depression.

10 Nov 2010

First Edition: November 10, 2010

Today's headlines include new survey results regarding employers' and the insurance coverage they provide to employees, as well as more details on health insurance open season.

10 Nov 2010

Fibroblast growth factor-2 stimulates periodontal regeneration: Study

It is well known that oral infection progressively destroys periodontal tissues and is the leading cause of tooth loss in adults. A major goal of periodontal treatment is regeneration of the tissues lost to periodontitis. Unfortunately, most current therapies cannot predictably promote repair of tooth-supporting defects. A variety of regenerative approaches have been used clinically using bone grafts and guiding tissue membranes with limited success.

10 Nov 2010

Myrexis presents key preclinical findings of MPI-0485520 at ACR/ARHP meeting

Myrexis, Inc., a biotechnology company focused on discovering, developing, and commercializing novel treatments for cancer, today presented key preclinical findings of the Company's novel oral anti-interferon, MPI-0485520, at the 74th Annual Scientific Meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals, in Atlanta, Georgia.

10 Nov 2010

Jefferson awarded $2.6M grant for study on cognitive decline in older African Americans with MCI

Researchers in the Departments of Psychiatry and Neurology at Jefferson Medical College of Thomas Jefferson University were recently awarded a $2.6 million grant from The National Institute of Health to study whether increasing participation in cognitive, physical and/or social activities prevents cognitive decline in older African Americans with Mild Cognitive Impairment (MCI).

10 Nov 2010

Researchers to determine levels of stroke risk in patients with narrowed brain arteries

Neurological researchers at Rush University Medical Center are part of a multicenter, National Institutes of Health (NIH) study to determine the levels of stroke risk and stroke recurrence in patients with narrowed brain arteries.

10 Nov 2010

Therapy News and Research

Nplate reduces treatment failure and splenectomies in adults with chronic immune thrombocytopenia

Depression associated with molecular-level disturbance in body's 24-hour clock

BCBS of Michigan alleged to have crushed pilot physical therapy program it saw as competition

Nutech Mediworld founder presents clinical study results of hESC therapy in patients with spinal cord injury

tDCS electric stimulation can improve motor function in stroke patients

Researchers find text messages to HIV patients improve adherence, health outcomes in Kenya trial

Vertex to enroll additional treatment arm in telaprevir/VX-222 Phase 2 clinical trial for HCV

New stem cell gene, enzyme replacement treatment for Tay-Sachs disease

Amarin reports $31.4 million cash balance for third quarter 2010

Statins benefit ‘at risk’ patients but are underused: Study

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Zalicus third quarter total revenue decreases to $1.2 million

Hormones and stress are major contributors to depression in women who undergo IVF

Researchers identify molecular cascade that drives process of reconnection in adult brain after stroke

Receptive music therapy associated with reduced depressive symptoms

First Edition: November 10, 2010

Fibroblast growth factor-2 stimulates periodontal regeneration: Study

Myrexis presents key preclinical findings of MPI-0485520 at ACR/ARHP meeting

Jefferson awarded $2.6M grant for study on cognitive decline in older African Americans with MCI

Researchers to determine levels of stroke risk in patients with narrowed brain arteries

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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