Cancer Therapy News and Research

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FBH1 gene helps turn up the effect of chemotherapy

Chemotherapy is one of the most common treatments for cancer patients. However, many patients suffer from serious side-effects and a large proportion does not respond to the treatment. Researchers from the Biotech Research and Innovation Centre (BRIC) and Center for Healthy Aging, University of Copenhagen, now show that the gene FBH1 helps turn up the effect of chemotherapy.

30 Jan 2013

Phenformin decreases size of lung tumors and increases survival in mice

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work against cancer.

30 Jan 2013

Emotional stress can reduce prostate cancer drugs’ effectiveness

Not surprisingly, a cancer diagnosis creates stress. And patients with prostate cancer show higher levels of anxiety compared to other cancer patients. A new study by researchers at Wake Forest Baptist Medical Center indicates that stress is not just an emotional side effect of the diagnosis; it also can reduce the effectiveness of prostate cancer drugs and accelerate the development of prostate cancer.

29 Jan 2013

European radiotherapy provision has ‘significant shortfalls’

A review published in The Lancet Oncology reveals significant shortfalls in radiotherapy equipment and manpower across Europe.

28 Jan 2013

Certain forms of abuse negatively influence women cancer patients' quality of life

A new study by University of Kentucky researchers shows evidence that certain forms of abuse negatively influence women cancer patients' quality of life.

28 Jan 2013

Reducing the level of mutant p53 gene increases susceptibility to cancer treatment

Scientists from the National Cancer Centre Singapore (NCCS) have discovered the workings of the gene that has been hindering treatment response in cancer patients. This discovery was made after 5 years of studying the mutant form of the p53 gene, the major tumor suppressor in humans, which is generally found mutated in over 50% of all type of human cancers.

27 Jan 2013

Tailored treatments and PSA screenings required to improve health outcomes in Ghana

Infectious diseases in Ghana tend to capture the most attention, but a quiet crisis may soon take over as the country's most threatening epidemic: cancer.

25 Jan 2013

Researchers identify cancer-associated mutations

Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't been previously found.

25 Jan 2013

Study shows promising results for cancer treatment

The plasma membrane transporter SLC5A8 can inhibit the spread of tumours by decreasing the amount of the anti-apoptotic protein surviving in tumour cells.

25 Jan 2013

Biomedical engineers identify natural switch that controls breast cancer metastasis

With a desire to inhibit metastasis, Cornell biomedical engineers have found the natural switch between the body's inflammatory response and how malignant breast cancer cells use the bloodstream to spread.

24 Jan 2013

Keeping healthy blood cells alive could help fight leukaemia

Instead of focusing on the elimination of cancer cells, maintaining a stable population of healthy blood cells in the bone marrow could be the most effective way to fight against leukaemia.

23 Jan 2013

Smoking cessation helps prevent cancer relapse after surgery

Lung and head and neck cancer patients who smoked before surgery are more likely to relapse than those who had quit before surgery, Moffitt Cancer Center researchers say. They found that smoking-relapse prevention interventions are needed immediately after surgery to help prevent relapse.

23 Jan 2013

SLU team discovers molecular pathway that contributes to triple-negative breast cancer

In research published in the Jan. 17 issue of The Journal of Cell Biology, a team led by Susana Gonzalo, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, has discovered a molecular pathway that contributes to triple-negative breast cancer, an often deadly and treatment resistant form of cancer that tends to strike younger women.

23 Jan 2013

Bevacizumab QoL impact highlighted in ovarian cancer patients

The ICON7 study results suggest that improved progression-free survival with bevacizumab therapy for high-risk ovarian cancer may come at the cost of health-related quality of life.

21 Jan 2013

New study: Loneliness can harm overall health

New research links loneliness to a number of dysfunctional immune responses, suggesting that being lonely has the potential to harm overall health.

20 Jan 2013

New method can visualize aging and tumor growth in real-time

In a study published in the January 18 issue of Cell, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have developed a new method to visualize aging and tumor growth in mice using a gene closely linked to these processes.

18 Jan 2013

Sabutoclax appears to selectively target leukemia stem cells that are responsible for relapses

Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive - and thus vulnerable - to a novel cancer stem cell-targeting drug currently under development.

18 Jan 2013

Cancer Therapy News and Research

FBH1 gene helps turn up the effect of chemotherapy

Phenformin decreases size of lung tumors and increases survival in mice

Emotional stress can reduce prostate cancer drugs’ effectiveness

European radiotherapy provision has ‘significant shortfalls’

Certain forms of abuse negatively influence women cancer patients' quality of life

Reducing the level of mutant p53 gene increases susceptibility to cancer treatment

Tailored treatments and PSA screenings required to improve health outcomes in Ghana

Researchers identify cancer-associated mutations

Study shows promising results for cancer treatment

Biomedical engineers identify natural switch that controls breast cancer metastasis

Keeping healthy blood cells alive could help fight leukaemia

Smoking cessation helps prevent cancer relapse after surgery

SLU team discovers molecular pathway that contributes to triple-negative breast cancer

Bevacizumab QoL impact highlighted in ovarian cancer patients

New study: Loneliness can harm overall health

New method can visualize aging and tumor growth in real-time

Sabutoclax appears to selectively target leukemia stem cells that are responsible for relapses

Boehringer Ingelheim receives FDA Priority Review for afatinib to treat EGFR mutation-positive NSCLC

Scientists to investigate how cancer cells hide to avoid chemotherapy drugs

Researchers discover molecular blueprint behind the IFIT protein

Your guide to microplate readers for cancer research eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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