Fatigue News and Research

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Imatinib-related symptom burden linked to adherence in Indian CML patients

Research shows low adherence to imatinib in Indian patients with chronic myeloid leukaemia, with an association between nonadherence and worse symptom burden related to treatment.

21 Apr 2016

Existing cancer drugs may be able to help people with enlarged heart cells

UT Southwestern Medical Center cardiology researchers have identified molecular ties between the growth of cancer cells and heart cells that suggest existing cancer drugs may be able to help those with enlarged heart cells -- a condition that can lead to heart attacks and stroke.

18 Apr 2016

LOXO-101 drug shows efficacy with tumor regression in varied types of genetically defined cancer

A phase I study of the drug LOXO-101 appears to significantly reduce tumors in patients with varied types of genetically defined cancer, according to a study led by The University of Texas MD Anderson Cancer Center.

18 Apr 2016

Study shows safety of experimental drug guadecitabine in colorectal cancer patients

In a small, phase I clinical trial, Johns Hopkins Kimmel Cancer Center researchers say they show for the first time that the experimental drug guadecitabine (SGI-110) is safe in combination with the chemotherapy drug irinotecan and may overcome resistance to irinotecan in patients with metastatic colorectal cancer.

18 Apr 2016

Study shows noise impairs tactile abilities of premature babies

Premature birth is a harsh change of environment for a baby. Until birth, the baby is confined to the mother's womb, surrounded by soft lighting and filtered noise. When infants are born, they are attacked by several visual, sound, and tactile stimulations.

16 Apr 2016

AbbVie's ABT-493 and ABT-530 achieve high SVR rates in GT1 chronic HCV patients who failed previous therapy with DAAs

AbbVie, a global biopharmaceutical company, today announced that 91 percent (n=20/22) of genotype 1 (GT1) chronic hepatitis C virus (HCV) infected patients who failed previous therapy with direct-acting antivirals (DAAs) achieved SVR12 with 12 weeks of ABT-493 and ABT-530 with ribavirin (RBV) in the primary intent-to-treat analysis.

15 Apr 2016

VIEKIRAX and EXVIERA achieve high SVR rates in GT1 and GT4 hepatitis C virus infected patients

AbbVie, a global biopharmaceutical company, today announced new real-world data showing 96 percent of genotype 1 (GT1) patients (n=486/505 assessable for analysis) and 100 percent (n=53/53) of genotype 4 (GT4) patients achieved sustained virologic response at 12 weeks post-treatment (SVR12).

15 Apr 2016

Innate Immunotherapeutics announces clinical trial fully enrolled and receives strong interest from potential Pharma partners

Innate Immunotherapeutics Limited has closed enrolment into the Company's Phase 2B placebo controlled efficacy trial of MIS416 in patients with secondary progressive multiple sclerosis (SPMS). The study has exceeded the original recruitment target of 90 subjects with the successful enrolment this week of the 93rd patient.

14 Apr 2016

Minimally important dyspnoea, fatigue changes in PAH patients defined

Researchers say that a change of around 1 unit in Borg dyspnoea or fatigue scores signifies an important change in patients with pulmonary arterial hypertension.

13 Apr 2016

New KidsMD Alexa skill device allows parents to get easier to access medical information

"My child has a fever of 101. Should I be concerned?" Through a new skill created for Amazon Alexa-enabled devices, parents will now be able to ask Alexa a variety of questions around fever and other common symptoms. The KidsMD Alexa skill was developed by the Innovation & Digital Health Accelerator team at Boston Children's Hospital and launched today.

13 Apr 2016

Common antihistamine may partially reverse damage to visual system in multiple sclerosis patients

A common antihistamine used to treat symptoms of allergies and the common cold, called clemastine fumarate, partially reversed damage to the visual system in people with multiple sclerosis (MS) in a preliminary study released today that will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

13 Apr 2016

Inserm study reveals potential of secondary system to improve heart function

Heart failure affects over one million people in France. Although the blood system is the first to have been explored for the purpose of improving heart function, a study by Inserm has revealed the potential of a secondary system that had previously received scant attention.

13 Apr 2016

Noviplex card could accelerate testing for Zika virus in the Amazonian region of Brazil

A University of Nebraska-Lincoln researcher is partnering with Brazilian officials to distribute a device that could accelerate testing for the Zika virus and monitor contamination of the country's freshwater food sources.

11 Apr 2016

Orthopedic wear and mechanical testing webinar to be hosted by Lucideon

Lucideon, the international materials technology company, together with Knight Mechanical Testing, is hosting a webinar entitled ‘Wear and Mechanical Testing of Hips and Knees - What the Standards Don’t Tell You’ on the 28th April at 3PM (UK time) 10AM (EST).

From Lucideon 8 Apr 2016

Radiation therapy plus PCV chemotherapy improves survival of low-grade glioma patients

Patients with a low-grade type of brain tumor called glioma who received radiation therapy plus a chemotherapy regimen, including procarbazine, lomustine and vincristine (PCV), experienced a longer progression-free survival and overall survival than patients who received radiation therapy alone, according to the results of the clinical trial, Radiation Therapy Oncology Group 9802 published in the April 7 issue of the New England Journal of Medicine.

7 Apr 2016

Parkinson's disease medications could lead to impulse control disorders

Drugs commonly prescribed to treat Parkinson's disease have been linked to impulse control disorders such as pathological gambling, compulsive buying, hypersexuality and binge eating in some patients, report neurologists from Loyola Medicine and Loyola University Chicago Stritch School of Medicine.

6 Apr 2016

Two established atrial fibrillation ablation techniques show similar effects, safety outcomes

Two established techniques for correcting the root cause of the heart rhythm disorder atrial fibrillation show similar effects and safety outcomes, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

Blast-related concussions result in hormone changes that lead to poor quality of life among veterans

A study in military veterans finds that explosive blast-related concussions frequently result in hormone changes leading to problems such as sleep disturbances, fatigue, depression and poor quality of life. The research, to be presented Saturday at the Endocrine Society's 98th annual meeting in Boston, evaluated hormone levels in 41 male veterans who had been deployed to Iraq or Afghanistan.

4 Apr 2016

Wear and medical device testing seminars to be run by Lucideon and STC in China

US and UK-based Lucideon, the materials technology company, and Hong Kong Standards and Testing Centre (STC), the testing, inspection and certification organization based in Hong Kong and China, are offering orthopaedic implant manufacturers in the Asia region, and their supply chain, a series of seminars on wear testing and medical devices testing.

From Lucideon 4 Apr 2016

Investigators predict that new pneumonia epidemic in Beijing will likely to continue for longer time

Mycoplasma pneumoniae infections began rising in Beijing last spring, and by December, this pathogen was found in more than half of hospitalized children suffering from pneumonia in that city, according to investigators from the Capital Institute of Pediatrics, Beijing, China.

2 Apr 2016

Fatigue News and Research

Imatinib-related symptom burden linked to adherence in Indian CML patients

Existing cancer drugs may be able to help people with enlarged heart cells

LOXO-101 drug shows efficacy with tumor regression in varied types of genetically defined cancer

Study shows safety of experimental drug guadecitabine in colorectal cancer patients

Study shows noise impairs tactile abilities of premature babies

AbbVie's ABT-493 and ABT-530 achieve high SVR rates in GT1 chronic HCV patients who failed previous therapy with DAAs

VIEKIRAX and EXVIERA achieve high SVR rates in GT1 and GT4 hepatitis C virus infected patients

Innate Immunotherapeutics announces clinical trial fully enrolled and receives strong interest from potential Pharma partners

Minimally important dyspnoea, fatigue changes in PAH patients defined

New KidsMD Alexa skill device allows parents to get easier to access medical information

Common antihistamine may partially reverse damage to visual system in multiple sclerosis patients

Inserm study reveals potential of secondary system to improve heart function

Noviplex card could accelerate testing for Zika virus in the Amazonian region of Brazil

Orthopedic wear and mechanical testing webinar to be hosted by Lucideon

Radiation therapy plus PCV chemotherapy improves survival of low-grade glioma patients

Parkinson's disease medications could lead to impulse control disorders

Two established atrial fibrillation ablation techniques show similar effects, safety outcomes

Blast-related concussions result in hormone changes that lead to poor quality of life among veterans

Wear and medical device testing seminars to be run by Lucideon and STC in China

Investigators predict that new pneumonia epidemic in Beijing will likely to continue for longer time

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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