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Study identifies gaps in primary health care for seniors with multiple chronic conditions

The number of health care services seniors use is determined more by the number of chronic conditions they have than by their age, according to a new study from the Canadian Institute for Health Information.

28 Jan 2011

FDA schedules fourth orphan drug designation workshop

The U.S. Food and Drug Administration has scheduled its fourth orphan drug designation workshop for academics, biotechnology companies, and those unfamiliar with the process for Feb. 28 – March 1, 2011, in Claremont, Calif. in collaboration with Keck Graduate Institute.

28 Jan 2011

API2-MALT1 fusion protein appears to trigger cancer

What happens when two proteins join together? In this case, they become like a power couple, where the whole is greater than the sum of the parts. API2 and MALT1 are two proteins that become fused together in a subset of lymphomas. The API2 part of the fusion connects with an enzyme called NIK. When it does, MALT1 comes in for the kill, splitting NIK in two, a process called cleavage.

28 Jan 2011

Tibotec grants multiple non-exclusive licenses to generic manufacturers for rilpivirine hydrochloride

Tibotec Pharmaceuticals today announced that it has granted multiple non-exclusive licenses to generic manufacturers including Hetero Drugs Limited, Matrix Laboratories Limited (a Mylan company) of India and Aspen Pharmacare of South Africa to manufacture, market and distribute the investigational non-nucleoside reverse transcriptase inhibitor rilpivirine hydrochloride (TMC278), pending its approval for use with other antiretroviral agents in the treatment of treatment-naive HIV-1 infected adults.

28 Jan 2011

New research: Retired NFL players more likely to misuse painkillers

Retired NFL players use painkillers at a much higher rate than the rest of us, according to new research conducted by investigators at Washington University School of Medicine in St. Louis.

28 Jan 2011

Frequency of analgesic drug errors in hospitals is nearly 3 per 1000 prescriptions: Study

The frequency of analgesic drug errors in hospitals is nearly 3 per 1,000 prescriptions, based on a study performed in a 631-bed tertiary care facility and published in The Journal of Pain, the peer-review journal of the American Pain Society.

28 Jan 2011

CSL Behring receives marketing approval for HAE drug Berinert in Israel

CSL Behring announced today it has been granted national marketing authorization in Israel to market Berinert® for the treatment of acute hereditary angioedema (HAE) attacks in any body location. With this most recent approval, Berinert is now licensed in 30 countries, including Europe, Japan, North America, South America and Australia.

28 Jan 2011

McGill, GSK enter collaborative research agreement on cystic fibrosis

McGill University and GlaxoSmithKline plc have signed a collaboration agreement to develop a potential breakthrough approach to treat cystic fibrosis, a fatal genetic disease. The trans-Atlantic effort between researchers from McGill's Faculty of Medicine and their GSK collaborators in the UK, will focus on developing molecules that could treat the disease by correcting the dysfunction caused by the mutated gene.

28 Jan 2011

Interim results from ganetespib Phase 2 trial in NSCLC to be presented at 11th IASLC annual meeting

Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that Dr. Jonathan Goldman, M.D., Premiere Oncology will present interim results from a Phase 2 trial of ganetespib in non-small cell lung cancer at the International Association for the Study of Lung Cancer 11th Annual Targeted Therapies for the Treatment of Lung Cancer Meeting.

28 Jan 2011

Discovery of aldose reductase enzyme can result in new therapies for asthma and COPD

Researchers have proved that a single "master switch" enzyme, known as aldose reductase, is key in producing excess mucous that clogs the airways of people with asthma and chronic obstructive pulmonary disease.

28 Jan 2011

Placental colonization by bacteria could lead to preterm birth and other developmental problems

The type of bacteria that colonize the placenta during pregnancy could be associated with preterm birth and other developmental problems in newborns according to research published in the current issue of the online journal mBio-.

28 Jan 2011

Boston Scientific reports first U.S. use of Blazer Open-Irrigated Catheter in BLOCk-CTI clinical trial

Boston Scientific Corporation today announced the first use of the Blazer® Open-Irrigated Catheter in the U.S. as part of the BLOCk-CTI clinical trial. BLOCk-CTI is a prospective, randomized trial evaluating the safety and effectiveness of the Blazer Open-Irrigated Catheter in patients with sustained or recurrent Type 1 atrial flutter.

28 Jan 2011

Cognitive training may help end hijacking of imagination by drugs of abuse

The growing numbers of new cases of substance abuse disorders are perplexing. After all, the course of drug addiction so often ends badly. The negative consequences of drug abuse appear regularly on TV, from stories of celebrities behaving in socially inappropriate and self-destructive ways while intoxicated to dramatization of the rigors of drug withdrawal on "Intervention" and other reality shows.

28 Jan 2011

H3 Biomedicine introduces cancer research and development operations in Cambridge

H3 Biomedicine today announced that it has launched research and development operations in Cambridge, Massachusetts. H3 Biomedicine will undertake a comprehensive approach to breakthrough oncology treatments based on two primary principles: 1) the genetics of patients' cancers can reveal drug targets tailored to their cancers and 2) the advances in modern chemistry enable the discovery of new classes of safe and effective drugs against these targets.

27 Jan 2011

HIV drug used by drug abusers in a deadly concoction

In a sad and rather ironic situation in South Africa, where many are fighting a battle against HIV/AIDS with shortage of Anti-retrovital drugs, there is a new drug craze. South Africa has the world’s largest population of HIV infected citizens - nearly 6 million.

27 Jan 2011

Baxter fourth quarter net income declines 26% to $423 million

Baxter International Inc. today announced its financial results for the fourth quarter of 2010, and provided its financial outlook for the first quarter and full-year 2011.

From Baxter International Inc. 27 Jan 2011

St. Michael's Hospital to build first automated high-throughput zebrafish screening facility in Canada

Zebrafish are the new fruit flies.

27 Jan 2011

The Food Integrity and Traceability Conference to take place at Queen's University Belfast

As food scares, such as the recent detection of dioxins in eggs from Germany, become more frequent, the public should be reassured that advances in science are helping reduce the risks from eating contaminated foods.

27 Jan 2011

TD2 and Flagship Biosciences offer combined oncology and pathology services

TGen Drug Development (TD2) and Flagship Biosciences today announced a strategic alliance that should help speed new drugs safely into human testing and quickly benefit cancer patients.

27 Jan 2011

Biotage announces release of new Analytical Sample Preparation Catalog

Biotage, a leading supplier of tools and technology for medicinal and analytical chemistry, announced the release of its new Analytical Sample Preparation Catalog. The expanded, 200-page catalog includes a range of products for Bioanalytical, Forensic, Clinical, Environmental, Agrochemical and Food Applications.

27 Jan 2011

Drugs News and Research

Study identifies gaps in primary health care for seniors with multiple chronic conditions

FDA schedules fourth orphan drug designation workshop

API2-MALT1 fusion protein appears to trigger cancer

Tibotec grants multiple non-exclusive licenses to generic manufacturers for rilpivirine hydrochloride

New research: Retired NFL players more likely to misuse painkillers

Frequency of analgesic drug errors in hospitals is nearly 3 per 1000 prescriptions: Study

CSL Behring receives marketing approval for HAE drug Berinert in Israel

McGill, GSK enter collaborative research agreement on cystic fibrosis

Interim results from ganetespib Phase 2 trial in NSCLC to be presented at 11th IASLC annual meeting

Discovery of aldose reductase enzyme can result in new therapies for asthma and COPD

Placental colonization by bacteria could lead to preterm birth and other developmental problems

Boston Scientific reports first U.S. use of Blazer Open-Irrigated Catheter in BLOCk-CTI clinical trial

Cognitive training may help end hijacking of imagination by drugs of abuse

H3 Biomedicine introduces cancer research and development operations in Cambridge

HIV drug used by drug abusers in a deadly concoction

Baxter fourth quarter net income declines 26% to $423 million

St. Michael's Hospital to build first automated high-throughput zebrafish screening facility in Canada

The Food Integrity and Traceability Conference to take place at Queen's University Belfast

TD2 and Flagship Biosciences offer combined oncology and pathology services

Biotage announces release of new Analytical Sample Preparation Catalog

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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