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Researchers uncover role of epigenetic changes in Alzheimer's disease

A team led by researchers at the University of Exeter Medical School and King's College London has uncovered some of the strongest evidence yet that epigenetic changes in the brain play a role in Alzheimer's disease.

19 Aug 2014

Study shows bryostatin plays key role in slowing or reversing Alzheimer's disease

Neurotrope, Inc. (OTCQB: NTRP) today announced that results from a new study, entitled, "PKCe Deficits in Alzheimer's Disease Brains and Skin Fibroblasts," published in the recent edition of the peer-reviewed Journal of Alzheimer's Disease and co-authored by Tapan K. Khan, Ph.D.; Abhik Sen, Ph.D.; Jarin Hongpaisan, Ph.D.; Chol S. Lim, Ph.D.; Thomas J. Nelson, Ph.D., and; Dr. Daniel L. Alkon, each of the Blanchette Rockefeller Neurosciences Institute (BRNI), provide further indication of the role that protein kinase C epsilon (PKCe) may play in the potential treatment of Alzheimer's disease (AD).

19 Aug 2014

Study confirms close link between immune system and adult neurogenesis

A new study by Barbara Beltz, the Allene Lummis Russell Professor of Neuroscience at Wellesley College, and Irene Soderhall of Uppsala University, Sweden, published in the August 11 issue of the journal Developmental Cell, demonstrates that the immune system can produce cells with stem cell properties, using crayfish as a model system. These cells can, in turn, create neurons in the adult animal.

19 Aug 2014

Novartis and Gamida Cell sign Option and Investment Agreements

Elbit Imaging Ltd. announced today that Elbit Medical Technologies Ltd., a subsidiary of the Company in which it holds approximately 86% of the voting power, announced that on August 18, 2014, Gamida Cell Ltd., in which Elbit Medical holds approximately 30.8% of the voting power and a vast majority of Gamida Cell's shareholders (including Elbit Medical), signed Option and Investment Agreements with Novartis Pharma AG (Novartis).

19 Aug 2014

NASA study reveals how spaceflight affects immune system of crew members

There is nothing like a head cold to make us feel a little dazed. We get things like colds and the flu because of changes in our immune system. Researchers have a good idea what causes immune system changes on Earth-think stress, inadequate sleep and improper nutrition.

19 Aug 2014

Research findings call for clinical testing of relevant drugs to prevent NASH

Non-alcoholic fatty liver disease (NAFLD) is a common affliction, affecting almost 30 percent of Americans, with a significant number suffering from its most severe form, called non-alcoholic steatohepatitis or NASH, which can lead to cirrhosis and liver cancer. In recent years, NASH has become the leading cause of liver transplantation.

19 Aug 2014

Targeting club cells may help shorten duration of flu symptoms

A specialized subset of lung cells can shake flu infection, yet they remain stamped with an inflammatory gene signature that wreaks havoc in the lung, according to a study published in The Journal of Experimental Medicine.

19 Aug 2014

Innate lymphoid cells induce specific T and B cell responses during inflammation

In case of an inflammation the body releases substances that increase the immune defense. During chronic inflammation, this immune response gets out of control and can induce organ damage.

19 Aug 2014

MGH-developed microfluidic device may help study key steps involved in development of tumor metastasis

A microfluidic device developed at Massachusetts General Hospital may help study key steps in the process by which cancer cells break off from a primary tumor to invade other tissues and form metastases.

19 Aug 2014

UC Santa Cruz cancer researcher receives $350,000 to develop novel drugs for breast cancer

UC Santa Cruz cancer researcher Seth Rubin has received a $350,000 grant to fund his work toward the development of a new class of drugs for treating breast cancer. The grant is a Breast Cancer Research Program Breakthrough Award from the congressionally directed medical research programs of the U.S. Department of Defense.

19 Aug 2014

Globavir plans to seek approval, launch novel drug for treatment of Ebola infection

Globavir Biosciences, Inc., a biotechnology company developing therapeutics to treat infectious diseases, has announced intentions to develop its lead drug candidate, GBV006, for the treatment of the current Ebola Virus outbreak in West Africa. Globavir will seek approval for the use of GBV006, a combination of Food and Drug Administration approved drugs, through an established compassionate use regulatory pathway.

19 Aug 2014

Lymphocyte count predicts papillary RCC patient survival

Lymphopenia is a significant predictor of outcome in patients undergoing surgery for papillary renal cell carcinoma, US researchers report.

18 Aug 2014

Researchers use microengineered device to show how EMT cancer cells migrate

Using a microengineered device that acts as an obstacle course for cells, researchers have shed new light on a cellular metamorphosis thought to play a role in tumor cell invasion throughout the body.

18 Aug 2014

ITS develops new T cell vaccine to protect humans from seasonal and pandemic influenza A

Immune Targeting Systems, specializing in the development of novel T cell immune therapies, has been developing an exciting new T cell vaccine (FlunisynTM) designed to protect humans from all strains of seasonal and pandemic influenza A.

18 Aug 2014

FDA-approved drug eliminates immune cells that destroys hair follicles in people with alopecia areata

Researchers at Columbia University Medical Center (CUMC) have identified the immune cells responsible for destroying hair follicles in people with alopecia areata, a common autoimmune disease that causes hair loss, and have tested an FDA-approved drug that eliminated these immune cells and restored hair growth in a small number of patients.

18 Aug 2014

Researchers use new gene editing method to correct mutation that leads to DMD

UT Southwestern Medical Center researchers successfully used a new gene editing method to correct the mutation that leads to Duchenne muscular dystrophy (DMD) in a mouse model of the condition.

17 Aug 2014

Research findings may lead to novel target for chemoresistant cancer cells

Dartmouth cancer researchers at Norris Cotton Cancer Center found a means of causing the elimination of a protein that maintains cancer cell viability; the results of the study appear in the August 8 issue of The Journal of Biological Chemistry.

17 Aug 2014

NIH challenges innovators to compete for prizes by developing new ways to track a single cell

The National Institutes of Health is challenging science innovators to compete for prizes totaling up to $500,000, by developing new ways to track the health status of a single cell in complex tissue over time.

16 Aug 2014

Scientists create computer algorithm for cell and tissue engineering

In a boon to stem cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a "roadmap" for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies.

16 Aug 2014

NIH-funded study explores how thalamic reticular nucleus influences consciousness

Ever wonder why it's hard to focus after a bad night's sleep? Using mice and flashes of light, scientists show that just a few nerve cells in the brain may control the switch between internal thoughts and external distractions.

16 Aug 2014

B Cell News and Research

Researchers uncover role of epigenetic changes in Alzheimer's disease

Study shows bryostatin plays key role in slowing or reversing Alzheimer's disease

Study confirms close link between immune system and adult neurogenesis

Novartis and Gamida Cell sign Option and Investment Agreements

NASA study reveals how spaceflight affects immune system of crew members

Research findings call for clinical testing of relevant drugs to prevent NASH

Targeting club cells may help shorten duration of flu symptoms

Innate lymphoid cells induce specific T and B cell responses during inflammation

MGH-developed microfluidic device may help study key steps involved in development of tumor metastasis

UC Santa Cruz cancer researcher receives $350,000 to develop novel drugs for breast cancer

Globavir plans to seek approval, launch novel drug for treatment of Ebola infection

Lymphocyte count predicts papillary RCC patient survival

Researchers use microengineered device to show how EMT cancer cells migrate

ITS develops new T cell vaccine to protect humans from seasonal and pandemic influenza A

FDA-approved drug eliminates immune cells that destroys hair follicles in people with alopecia areata

Researchers use new gene editing method to correct mutation that leads to DMD

Research findings may lead to novel target for chemoresistant cancer cells

NIH challenges innovators to compete for prizes by developing new ways to track a single cell

Scientists create computer algorithm for cell and tissue engineering

NIH-funded study explores how thalamic reticular nucleus influences consciousness

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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