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Discovery could lead to novel drugs to tackle melanoma

Skin Cancer cells work together to spread further and faster, according to a new study published in Cell Reports. The discovery could lead to new drugs to tackle melanoma, the most deadly form of skin cancer.

25 Jul 2014

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers at UC San Francisco (UCSF) have discovered that endostatin, a protein that once aroused intense interest as a possible cancer treatment, plays a key role in the stable functioning of the nervous system.

25 Jul 2014

Researchers working to develop new drugs for treating chronic inflammatory diseases

Science and industry are collaborating to develop future pharmaceuticals for treating chronic inflammatory diseases. The medicines will combat immunological processes that have gone wrong.

25 Jul 2014

Clinical study aims to validate preventive treatment against tumor metastasis

Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis. Managing to block the metastasis or, even better, prevent their formation would be a giant step towards the fight against cancer.

25 Jul 2014

Scientists one step closer to creating viable cell replacement therapy for multiple sclerosis patients

Scientists at The New York Stem Cell Foundation Research Institute are one step closer to creating a viable cell replacement therapy for multiple sclerosis from a patient's own cells.

25 Jul 2014

Kinex receives FDA approval to begin Phase I study of KX2-391 Ointment for actinic keratosis

Kinex Pharmaceuticals announced the receipt of an allowance by the US FDA for the Company's KX2-391 Ointment for the commencement of a Phase I clinical study in actinic keratosis. This is the Company's third IND to be allowed by the US FDA in the past 12 months.

25 Jul 2014

Compounds developed for cancer treatment show promise as potential oral therapy for Alzheimer's

Currently, no cure exists for Alzheimer's disease, the devastating neurological disease affecting more than 5 million Americans. But scientists are now reporting new progress on a set of compounds, initially developed for cancer treatment, that shows promise as a potential oral therapy for Alzheimer's. Their study appears in ACS' Journal of Medicinal Chemistry.

24 Jul 2014

Study identifies three genetic changes linked to increased risk of breast cancer in East Asian women

A new study in East Asian women has identified three genetic changes linked to an increased risk of breast cancer. The research, led by Vanderbilt University investigators, was published online July 20 in Nature Genetics.

24 Jul 2014

NYSCF and Beyond Batten Disease Foundation partner to find cure for juvenile Batten disease

The New York Stem Cell Foundation (NYSCF) and Beyond Batten Disease Foundation (BBDF) have partnered to develop stem cell resources to investigate and explore new treatments and ultimately find a cure for juvenile Batten disease, a fatal illness affecting children.

24 Jul 2014

Capsazepine shows dramatic tumor shrinkage without damaging surrounding tissues

Mouse models of human oral cancer treated with an agent called capsazepine showed dramatic tumor shrinkage without damage to surrounding tissues, researchers from the School of Dentistry and School of Medicine at The University of Texas Health Science Center at San Antonio found.

24 Jul 2014

Zydelig gets FDA approval for treatment of patients with three types of blood cancers

The U.S. Food and Drug Administration today approved Zydelig (idelalisib) to treat patients with three types of blood cancers.

24 Jul 2014

Prognostic value of visceral plural invasion limited in part-solid lung cancer

Visceral plural invasion is a significant predictor of survival in patients with small solid lung tumours but not in patients with part-solid tumours, Japanese study findings indicate.

23 Jul 2014

Combined risk score enhances radiation pneumonitis prediction

Combining dose-volume histogram parameters with age and baseline pulmonary fibrosis score creates a novel predictive risk score that improves prediction of radiation pneumonitis in patients receiving concurrent chemoradiotherapy for non-small-cell lung cancer, research shows.

23 Jul 2014

Standard TFI definition still applies for relapsed SCLC classification

Italian researchers have confirmed that using a treatment-free interval cut-off of 60 days to classify relapsed small-cell lung cancer as sensitive or resistant can be regarded as the standard definition.

23 Jul 2014

Co-targeting strategies suggested for EGFR-TKI resistance in NSCLC

Researchers have identified additional resistance mechanisms that could be targeted to improve the efficacy of irreversible epidermal growth factor receptor-tyrosine kinase inhibitors in patients with non-small-cell lung cancer harbouring both EGFR and T790M mutations.

23 Jul 2014

CRIPTO1 role in TKI resistance elucidated

Overexpression of CRIPTO1 may explain intrinsic tyrosine kinase inhibitor resistance in around 10% of patients with non-small-cell lung cancer and endothelial growth factor receptor mutations, research indicates.

23 Jul 2014

Tulane University psychiatrist to study how parental bond with children leaves lasting genetic protection

Tulane University psychiatrist Dr. Stacy Drury has been given $2.4 million by the National Institutes of Health to test a provocative new theory - how well children bond with a parent in the first year of life leaves lasting genetic protection, potentially shielding them from disease risks well into adulthood.

23 Jul 2014

Autoimmune diseases share certain pathogenic mechanisms with cancer

Autoimmune disorders may share certain pathogenic mechanisms with cancer, according to a new report by George Washington University researcher Linda Kusner, Ph.D., published in PLOS ONE on July 22.

23 Jul 2014

Pilot study shows that anti-cancer drug can activate hidden HIV

A pilot study by HIV researchers from Aarhus University and Aarhus University Hospital in Denmark has shown that an anti-cancer drug can activate hidden HIV.

23 Jul 2014

Understanding how some cells in the brain and nervous system turn cancerous

Scientists from the Sloan-Kettering Institute for Cancer Research in New York with the help of Plymouth University Peninsula Schools of Medicine and Dentistry have completed research which for the first time brings us nearer to understanding how some cells in the brain and nervous system become cancerous.

23 Jul 2014

B Cell News and Research

Discovery could lead to novel drugs to tackle melanoma

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers working to develop new drugs for treating chronic inflammatory diseases

Clinical study aims to validate preventive treatment against tumor metastasis

Scientists one step closer to creating viable cell replacement therapy for multiple sclerosis patients

Kinex receives FDA approval to begin Phase I study of KX2-391 Ointment for actinic keratosis

Compounds developed for cancer treatment show promise as potential oral therapy for Alzheimer's

Study identifies three genetic changes linked to increased risk of breast cancer in East Asian women

NYSCF and Beyond Batten Disease Foundation partner to find cure for juvenile Batten disease

Capsazepine shows dramatic tumor shrinkage without damaging surrounding tissues

Zydelig gets FDA approval for treatment of patients with three types of blood cancers

Prognostic value of visceral plural invasion limited in part-solid lung cancer

Combined risk score enhances radiation pneumonitis prediction

Standard TFI definition still applies for relapsed SCLC classification

Co-targeting strategies suggested for EGFR-TKI resistance in NSCLC

CRIPTO1 role in TKI resistance elucidated

Tulane University psychiatrist to study how parental bond with children leaves lasting genetic protection

Autoimmune diseases share certain pathogenic mechanisms with cancer

Pilot study shows that anti-cancer drug can activate hidden HIV

Understanding how some cells in the brain and nervous system turn cancerous

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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