Cancer Therapy News and Research

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Perceived reduction in penis size linked to regrets of prostate cancer treatment choice

A small percentage of men in a prostate cancer study complained that their penis seemed shorter following treatment, with some saying that it interfered with intimate relationships and caused them to regret the type of treatment they chose.

3 Jan 2013

Key regulator of energy metabolism in cancer cells may play a crucial role in restricting cancer cell growth

Researchers at McGill University have discovered that a key regulator of energy metabolism in cancer cells known as the AMP-activated protein kinase (AMPK) may play a crucial role in restricting cancer cell growth. AMPK acts as a "fuel gauge" in cells; AMPK is turned on when it senses changes in energy levels, and helps to change metabolism when energy levels are low, such as during exercise or when fasting.

28 Dec 2012

Genetic differences in enzyme CYP2D6 play a key role in effectiveness of tamoxifen for breast cancer

For nearly a decade, breast cancer researchers studying the hormone therapy tamoxifen have been divided as to whether genetic differences in a liver enzyme affect the drug's effectiveness and the likelihood breast cancer will recur.

27 Dec 2012

Scientists design small molecules that recognize myotonic dystrophy-associated RNAs

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a new approach to alter the function of RNA in living cells by designing molecules that recognize and disable RNA targets. As a proof of principle, in the new study the team designed a molecule that disabled the RNA causing myotonic dystrophy.

21 Dec 2012

New work on Akt's role in cancer stem cell biology

The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, PhD and Weihua Li, co-first author, both from the Center for Resuscitation Sciences, Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, and Xiaowei Xu, Department of Pathology and Laboratory Medicine, appears in Molecular Cell.

21 Dec 2012

Patients with hypertension or diabetes have increased risk of cancer recurrence, survival

By all accounts, a combination of colon cancer, diabetes and high blood pressure can be a recipe for medical disaster. Now, a new study led by a surgical oncologist and researcher at Temple University School of Medicine and Fox Chase Cancer Center has shown just how deadly this mix can be.

20 Dec 2012

Investigators report non-coding miRNAs as appealing biomarkers for cancer malignancy

As many as 50 percent of all human protein-coding genes are regulated by microRNA (miRNA) molecules. While some miRNAs impact onset and progression of cancer, others can actually suppress the development of malignant tumors and are useful in cancer therapy. They can also serve as potential biomarkers for early cancer detection. In a new issue of Cancer Biomarkers, investigators report on non-coding miRNAs as appealing biomarkers for malignancy.

20 Dec 2012

Personalized rectal cancer therapy shows promise

Personalized chemotherapy for rectal cancer results in high rates of pathologic response, indicate the results of a pilot study.

19 Dec 2012

MITF protein may help develop effective drug treatments for melanoma

Scientists at The University of Manchester have identified a protein that appears to hold the key to creating more effective drug treatments for melanoma, one of the deadliest cancers.

From The University of Manchester 19 Dec 2012

Numerous treatments exist for cancer-related fatigue, but few doctors recommend them to patients

Many people who have been through cancer and its treatment have trouble with their recovery because of severe, debilitating fatigue that can last for months or even years. But even though a variety of treatments exist for cancer-related fatigue, few doctors are recommending them to patients, according to a recent Mayo Clinic study appearing in Supportive Care in Cancer.

19 Dec 2012

British Pharmacological Society celebrates the start of annual meeting

The British Pharmacological Society (BPS) today celebrated the start of its annual meeting, which will cover the latest research in drug discovery over the next three days, including a special focus on discoveries in cancer treatment.

19 Dec 2012

Myostatin responsible for initiation of muscle loss: Study

A research study from Nanyang Technological University (NTU) has yielded important breakthroughs on how the body loses muscle, paving the way for new treatments for aging, obesity and diabetes.

19 Dec 2012

New report provides snapshot of Canada's cancer system

A comprehensive report released today by the Canadian Partnership Against Cancer provides a snapshot of how Canada's cancer system is performing in key areas from prevention through to patient experience and outcomes.

17 Dec 2012

New diagnostic innovations could refine the way doctors detect prostate cancer

Despite the volume of prostate cancer tests and treatments, experts and their patients are continually challenged to predict the disease's course and apply the most appropriate treatment. Now, two new diagnostic innovations – the PCA3 urine test and a more targeted prostate biopsy technique - could refine the way doctors diagnose prostate cancer and, subsequently, the way patients elect to treat it.

15 Dec 2012

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

Cancer scientists led by Dr. John Dick at the Princess Margaret Cancer Centre have found a way to follow single tumour cells and observe their growth over time. By using special immune-deficient mice to propagate human colorectal cancer, they found that genetic mutations, regarded by many as the chief suspect driving cancer growth, are only one piece of the puzzle. The team discovered that biological factors and cell behaviour - not only genes - drive tumour growth, contributing to therapy failure and relapse.

14 Dec 2012

At-home exercise regimen sufficient to increase cancer patients' mobility and reduce fatigue

It has been known for some time that exercise is important for cancer patients, but few studies have looked at the practicality of exercise programs and whether even a minimal workout can help.

14 Dec 2012

Opioids already in the body can enhance malignant tendencies of human cancer cells

A study led by University of Chicago researcher Patrick A. Singleton, Ph.D. and published in the journal Anesthesiology has shown that, even without the addition of further opioids such as morphine, opioids already in the body can enhance the malignant tendencies of human cancer cells.

13 Dec 2012

CRI, SU2C form Cancer Immunology Translational Research Dream Team

Stand Up To Cancer (SU2C) and the Cancer Research Institute (CRI) announce the formation of a Dream Team project dedicated to cancer immunology - "Immunologic Checkpoint Blockade and Adoptive Cell Transfer in Cancer Therapy."

13 Dec 2012

Review describes current state of lung cancer care

A review in the December issue of the journal Archives of Pathology & Laboratory Medicine by Paul Bunn Jr, MD, University of Colorado Cancer Center investigator and past president of ASCO, IASLC and AACI describes the current state of lung cancer care.

12 Dec 2012

Oncogene-induced senescence could play a key role in future cancer therapy

Cell aging, or cellular senescence, has an important role in the natural physiological response to tumor development. Activated oncogenes are able to induce senescence, and recent findings have suggested that oncogene-induced senescence (OIS) could play a key role in future cancer therapy.

12 Dec 2012

Cancer Therapy News and Research

Perceived reduction in penis size linked to regrets of prostate cancer treatment choice

Key regulator of energy metabolism in cancer cells may play a crucial role in restricting cancer cell growth

Genetic differences in enzyme CYP2D6 play a key role in effectiveness of tamoxifen for breast cancer

Scientists design small molecules that recognize myotonic dystrophy-associated RNAs

New work on Akt's role in cancer stem cell biology

Patients with hypertension or diabetes have increased risk of cancer recurrence, survival

Investigators report non-coding miRNAs as appealing biomarkers for cancer malignancy

Personalized rectal cancer therapy shows promise

MITF protein may help develop effective drug treatments for melanoma

Numerous treatments exist for cancer-related fatigue, but few doctors recommend them to patients

British Pharmacological Society celebrates the start of annual meeting

Myostatin responsible for initiation of muscle loss: Study

New report provides snapshot of Canada's cancer system

New diagnostic innovations could refine the way doctors detect prostate cancer

Biological factors, cell behaviour drive tumour growth contributing to therapy failure and relapse

At-home exercise regimen sufficient to increase cancer patients' mobility and reduce fatigue

Opioids already in the body can enhance malignant tendencies of human cancer cells

CRI, SU2C form Cancer Immunology Translational Research Dream Team

Review describes current state of lung cancer care

Oncogene-induced senescence could play a key role in future cancer therapy

Event guide: 7th Allogeneic Cell Therapies Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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