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Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study.

14 Oct 2015

Researchers identify new therapeutic target for Duchenne muscular dystrophy

Scientists have found what could one day lead to a promising treatment for those with a crippling disease, Duchenne muscular dystrophy.

14 Oct 2015

New breakthrough may provide key to understanding how to treat Muscular Dystrophy

New research published today in the journal eLife has demonstrated a new method for observing the behaviour of the protein Dystrophin in a living animal cell, in real-time. This breakthrough may provide a key to understanding how to treat the genetic disease, Muscular Dystrophy.

14 Oct 2015

Blocking the production of CHD4 protein may help increase effectiveness of AML treatments

Preclinical experiments led by a team of researchers at VCU Massey Cancer Center have shown that blocking the production of a protein known as chromodomain helicase DNA-binding protein 4 (CHD4) may help increase the effectiveness of first-line treatments for acute myeloid leukemia (AML), a particularly lethal blood cancer that is increasing in incidence among older adults.

14 Oct 2015

Malaria protein could one day help stop cancer

Scientists at the University of British Columbia, Vancouver Coastal Health and the BC Cancer Agency have discovered a protein from malaria that could one day help stop cancer in its tracks.

13 Oct 2015

Neighbourhood exposure to fast food outlets associated with lower BMD and BMC in newborns

New research from the MRC Lifecourse Epidemiology Unit at the University of Southampton in the UK indicates that neighbourhood exposure to fast food outlets is potentially linked to poorer bone development in early childhood.

13 Oct 2015

Danish researchers face possible breakthrough in fight against cancer

The hunt for a vaccine against malaria in pregnant women has provided an unexpected side benefit for Danish researchers, namely what appears to be an effective weapon against cancer. The scientists behind the vaccine aim for tests on humans within four years.

13 Oct 2015

Study: RNA editing technique shows promise in treating rare, severe form of muscular dystrophy

An RNA editing technique called "exon skipping" has shown preliminary success in treating a rare and severe form of muscular dystrophy that currently has no treatment, based on a new study from Northwestern Medicine and the University of Chicago. Children with the disease lose significant muscle strength early in life.

13 Oct 2015

Palm Beach Vapors unveils safe, fully customizable vaping technology for tobacco users

Millions of smokers worldwide have used vaping to help finally break free from the shackles of tobacco. An April 2015 study released by a team of researchers at Kings College London showed electronic cigarettes to be up to 95 percent less harmful than traditional cigarette smoking.

13 Oct 2015

Penn researchers lay groundwork for developing lncRNA-based tools for new cancer treatment

Growing insights about a significant, yet poorly understood, part of the genome - the "dark matter of DNA" -- have fundamentally changed the way scientists approach the study of diseases.

13 Oct 2015

Small heat shock protein as model for Alzheimer’s medication

In Alzheimer’s disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum München have now uncovered how the protein interacts with other proteins.

13 Oct 2015

Scientists create 3D image of key protein involved in blood and other cancer development

Scientists at the Walter and Eliza Hall Institute have created the first three-dimensional image of a key protein known to be involved in the development of blood and other cancers.

13 Oct 2015

Prostate Cells Undergo 'Reprogramming' To Form Tumors, Study Finds

Scientists have gained a key insight into how prostate tumors get their start - not by rewriting the normal DNA code, but by reprogramming the master regulator of genes in prostate cells to drive malignant growth.

12 Oct 2015

Study shows that IVIG could prevent brain atrophy, delay onset of Alzheimer's disease

In a Sutter Institute of Medical Research study published this month in the Journal of Neurology, Neurosurgery, and Psychiatry, the blood product intravenous immunoglobulin, or IVIG, was found to reduce brain atrophy and cognitive decline in patients in the early, pre-dementia phase of Alzheimer's disease.

12 Oct 2015

New clinical study focuses on investigational treatment to reduce impact of key protein from the brain

The Nantz National Alzheimer Center at Houston Methodist Hospital is part of a landmark clinical trial that looks at removing a key protein from the brain to prevent memory loss at least a decade before symptoms are noticed in healthy older adults.

12 Oct 2015

Researchers find protein that plays crucial role in development of allergic airway inflammation

Allergies are becoming more commonplace, particularly in industrialised coun-tries. In addition to hay fever, allergic asthma is currently considered to be one of the most widespread allergies. UFZ researchers and their colleagues from the University of Leipzig have recently been successful in finding a protein that plays a critical role in the development of allergic airway inflammation.

12 Oct 2015

Stem cell research to help combat congenital brittle bone disease

A study involving researchers from the Department of Genetics at the University of Leicester is to be conducted for the first time involving the transplantation of stem cells into foetuses with the brittle-bone disease osteogenesis imperfecta (OI), which causes repeated fractures, often before birth.

12 Oct 2015

York scientists target specific sodium channel to prevent breast cancer

Scientists at the University of York, using clinical specimens from charity Breast Cancer Now's Tissue Bank, have conducted new research into a specific sodium channel that indicates the presence of cancer cells and affects tumour growth rates.

12 Oct 2015

Glycan binding proteins modify parasite infection in cells of the heart muscle

Chagas disease is the main cause of infectious heart disease in Latin America. Researchers from the INGEBI and IBYME Institutes in Argentina explored the effect of glycan binding protein interactions between the human host and Typanosoma cruzi parasite. They found that a glycan binding protein expressed in humans modified the infection in cells of the heart muscle, showing the importance of galectins in the response to parasite infection.

12 Oct 2015

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis (MS). This is the first demonstration that introduction of blood in the healthy brain is sufficient to cause peripheral immune cells to enter the brain, which then go on to cause brain damage.

12 Oct 2015

G Protein News and Research

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers identify new therapeutic target for Duchenne muscular dystrophy

New breakthrough may provide key to understanding how to treat Muscular Dystrophy

Blocking the production of CHD4 protein may help increase effectiveness of AML treatments

Malaria protein could one day help stop cancer

Neighbourhood exposure to fast food outlets associated with lower BMD and BMC in newborns

Danish researchers face possible breakthrough in fight against cancer

Study: RNA editing technique shows promise in treating rare, severe form of muscular dystrophy

Palm Beach Vapors unveils safe, fully customizable vaping technology for tobacco users

Penn researchers lay groundwork for developing lncRNA-based tools for new cancer treatment

Small heat shock protein as model for Alzheimer’s medication

Scientists create 3D image of key protein involved in blood and other cancer development

Prostate Cells Undergo 'Reprogramming' To Form Tumors, Study Finds

Study shows that IVIG could prevent brain atrophy, delay onset of Alzheimer's disease

New clinical study focuses on investigational treatment to reduce impact of key protein from the brain

Researchers find protein that plays crucial role in development of allergic airway inflammation

Stem cell research to help combat congenital brittle bone disease

York scientists target specific sodium channel to prevent breast cancer

Glycan binding proteins modify parasite infection in cells of the heart muscle

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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