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Gene therapy shows promise for arrhythmogenic cardiomyopathy

Researchers evaluated the effectiveness of adeno-associated virus (AAV)-mediated Plakophilin 2 (PKP2) delivery in treating arrhythmogenic cardiomyopathy (ACM).

12 Dec 2023

Quizartinib extends life and enhances wellbeing for AML patients with key mutation

In a study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, patients recently diagnosed with a common and aggressive form of acute myeloid leukemia reported having improved quality of life when a newly approved drug was part of the treatment plan.

11 Dec 2023

Pandemic stressors overwhelm genetic resilience to depression in college students

Living through a historic pandemic while handling the stress of the first year of college sent one-third of students in a new study into clinical depression. That's double the percentage seen in previous years of the same study.

11 Dec 2023

Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

A Stanford Medicine-led, international study of hundreds of samples from patients with Hodgkin lymphoma has shown that levels of tumor DNA circulating in their blood can identify who is responding well to treatment and others who are likely to experience a disease recurrence - potentially letting some patients who are predicted to have favorable outcomes forgo lengthy treatment.

11 Dec 2023

MIT scientists develop nanoparticles to reduce inflammation in the brain

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy.

11 Dec 2023

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

Non-alcoholic fatty liver disease (NAFLD), characterized by excessive hepatic lipid accumulation, poses a high prevalence and can progress to cirrhosis and liver cancer.

11 Dec 2023

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

A new study from researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations provides insight into the underlying mechanisms of gene mutations commonly seen in patients with myelodysplastic syndromes (MDS) and other myeloid neoplasms.

11 Dec 2023

New atlas characterizes cellular landscape of the early human limb

Human fingers and toes do not grow outward; instead, they form from within a larger foundational bud, as intervening cells recede to reveal the digits beneath. This is among many processes captured for the first time as scientists unveil a spatial cell atlas of the entire developing human limb, resolved in space and time.

11 Dec 2023

New map offers valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer

Scientists have created the first extensive map showing how all possible genetic changes can affect health in the gene DDX3X, leading to valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer.

11 Dec 2023

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study demonstrates that inhibiting stromal class I histone deacetylases (HDACs) can effectively slow down pancreatic cancer progression, shedding light on a new therapeutic approach targeting the tumor microenvironment.

10 Dec 2023

Understanding why healthy cells help cancer cells to evade treatment

Chemotherapy becomes less effective because healthy cells push cancer cells to grow more slowly, according to two studies from researchers at UCL and Yale.

9 Dec 2023

Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds

Patients with low-risk ductal carcinoma in situ (DCIS) who skipped adjuvant radiotherapy after breast-conserving surgery had comparable five-year outcomes to those with high-risk DCIS who received adjuvant radiotherapy, according to results from the E4112 clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

Genome-wide study shows strong negative correlation between reproduction and lifespan

A University of Michigan-led study based on a review of genetic and health information from more than 276,000 people finds strong support for a decades-old evolutionary theory that sought to explain aging and senescence.

8 Dec 2023

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

It only takes holding your breath for slightly too long to understand that too little oxygen is bad for you. But can you also have too much? Indeed, breathing air with a higher oxygen level than your body needs can cause health problems or even death.

8 Dec 2023

Scientists decode key factor in T cell lymphoma growth, paving way for new treatments

A team from the Technical University of Munich (TUM) has decoded the factor that makes T cell lymphomas grow comparatively rapidly: A missing "emergency shut-off switch" results in the lymphomas processing particularly large amounts of sugar and triggers other processes as well.

8 Dec 2023

Genes News and Research

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Quizartinib extends life and enhances wellbeing for AML patients with key mutation

Pandemic stressors overwhelm genetic resilience to depression in college students

Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

MIT scientists develop nanoparticles to reduce inflammation in the brain

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

New atlas characterizes cellular landscape of the early human limb

New map offers valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Understanding why healthy cells help cancer cells to evade treatment

Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds

Genome-wide study shows strong negative correlation between reproduction and lifespan

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

Scientists decode key factor in T cell lymphoma growth, paving way for new treatments

Plant-based diets and genetic risk for obesity

Key gene linked to male bias in autism, Tourette's, and ADHD uncovered

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Flaxseed lignans found to influence gut microbiome and breast cancer risk

Researchers identify 25 new genetic markers linked to peptic ulcers

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo