Oral News and Research

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Colon cancer could be made more aggressive by common oral bacteria

Scientists have identified a common oral bacterium that accelerates colon cancer growth. The discovery could pave the way for new treatments.

5 Mar 2019

Researchers examine process of gut-based cells involved in long-term immunity

Only a few vaccines - for example, against polio and rotavirus - can be given orally. Most must be delivered by injection.

5 Mar 2019

Researchers find how common oral bacteria accelerates growth of colon cancer

Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum -- a common oral bacteria often implicated in tooth decay -- accelerates the growth of colon cancer. The study was published online in the journal EMBO Reports.

4 Mar 2019

Western Dental offers tips to prevent bad breath

Western Dental & Orthodontics has some advice for those who strive to maintain fresh breath.

4 Mar 2019

Health risks of smokeless tobacco product often misunderstood by American smokers

American smokers mistakenly think that using snus, a type of moist snuff smokeless tobacco product, is as dangerous as smoking tobacco, according to a Rutgers study.

4 Mar 2019

Failty evaluation can help determine patient's physical fitness for nonurgent operation

Frailty, a decline in function and resistance to short-term stress that typically occurs in old age, is linked to more complications after an operation among adults of all ages, according to researchers of a large new study published as an "article in press" on the Journal of the American College of Surgeons website in advance of print.

2 Mar 2019

Research shows how common fungus gets the flexibility to live in different host environments

The fungus Candida albicans is found in the gastrointestinal tract of about half of healthy adults with little if any effect, yet it also causes an oft-fatal blood infection among patients with compromised immune systems, including those with HIV/AIDS.

1 Mar 2019

Newly discovered drug targets could pave way for esophageal cancer therapeutics

Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma, the most common esophageal malignancy in the United States, according to new research out of Case Western Reserve University School of Medicine.

28 Feb 2019

Penn researchers cure nine HCV patients following heart transplants from infected donors

Nine patients at Penn Medicine have been cured of the Hepatitis C virus (HCV) following lifesaving heart transplants from deceased donors who were infected with the disease, according to a study published in the American Journal of Transplantation.

25 Feb 2019

Regular dietary peanut consumption after immunotherapy may extend allergy treatment benefits

Regular dietary peanut consumption after completing oral immunotherapy or sublingual immunotherapy for peanut allergy may provide continued protection against accidental exposures to the allergen, according to a new study led by Edwin Kim, MD, who presented the findings at the annual American Academy of Allergy, Asthma and Immunology conference in San Francisco.

25 Feb 2019

Egg oral immunotherapy could be safe way of desensitizing children, youth with egg allergy

UNC School of Medicine researcher Edwin Kim, MD, MS, says the results of a multi-year observational study are encouraging for those suffering from egg allergies.

25 Feb 2019

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Patients with Duchenne muscular dystrophy have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

23 Feb 2019

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

Patients with Duchenne muscular dystrophy (DMD) have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

21 Feb 2019

The American Heart Association issues new reference toolkit for healthcare providers

With nearly half of American adults having elevated blood pressure, it’s important for everyone to understand that some common habits may affect blood pressure, making the condition more difficult to control.

21 Feb 2019

Drug increases melanin production in some people with albinism

A small pilot clinical study at the National Eye Institute suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B, a rare genetic disease that causes pale skin and hair and poor vision.

21 Feb 2019

Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

In pharmaceutical companies, rats are used commonly in nonclinical studies to investigate the safety, efficacy, and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via the oral route are metabolized in the liver and intestine, so the metabolism is a key determinant of pharmacokinetics.

20 Feb 2019

Researchers uncover mechanisms that prevent tooth replacement in mice

Most reptiles and fish have multiple sets of teeth during their lifetime. However, most mammals, such as humans, have only one set of replacement teeth and some mammals, like mice, have only a single set with no replacement.

20 Feb 2019

Proper oral hygiene and regular visits to dentist can promote heart health

Proper oral hygiene and regular visits to the dentist can support cardiovascular health. This, in a nutshell, is what dental and heart experts agreed today at a joint workshop in Madrid.

19 Feb 2019

Cervical microbiome may influence HPV infection more than previously thought

Infections with a Human Papillomavirus cause 99 percent of cervical cancer cases, and the disease's first sign is often the appearance of precancerous lesions on a woman's cervix. But bacteria may play an important role, too.

19 Feb 2019

Female adolescent blood donors more likely to have iron deficiency and related anemia

Female adolescent blood donors are more likely to have low iron stores and iron deficiency anemia than adult female blood donors and nondonors, which could have significant negative consequences on their developing brains, a new study led by Johns Hopkins researchers suggests.

19 Feb 2019

Oral News and Research

Colon cancer could be made more aggressive by common oral bacteria

Researchers examine process of gut-based cells involved in long-term immunity

Researchers find how common oral bacteria accelerates growth of colon cancer

Western Dental offers tips to prevent bad breath

Health risks of smokeless tobacco product often misunderstood by American smokers

Failty evaluation can help determine patient's physical fitness for nonurgent operation

Research shows how common fungus gets the flexibility to live in different host environments

Newly discovered drug targets could pave way for esophageal cancer therapeutics

Penn researchers cure nine HCV patients following heart transplants from infected donors

Regular dietary peanut consumption after immunotherapy may extend allergy treatment benefits

Egg oral immunotherapy could be safe way of desensitizing children, youth with egg allergy

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

The American Heart Association issues new reference toolkit for healthcare providers

Drug increases melanin production in some people with albinism

Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

Researchers uncover mechanisms that prevent tooth replacement in mice

Proper oral hygiene and regular visits to dentist can promote heart health

Cervical microbiome may influence HPV infection more than previously thought

Female adolescent blood donors more likely to have iron deficiency and related anemia

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