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EZH2 enzyme drives aggressive tumor growth in treatment-resistant prostate cancer

An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in treatment-resistant prostate cancers, according to a new study by scientists at Weill Cornell Medicine.

20 Nov 2024

USC researchers receive $6 million to advance dry AMD treatment

The California Institute for Regenerative Medicine (CIRM), the state's stem cell agency, has awarded a two-year, $6 million grant to a team at the USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics and the USC Roski Eye Institute advancing a new treatment for one of the leading causes of blindness in older adults.

20 Nov 2024

CRISPR-based therapy shown to be safe, effective for people with transthyretin amyloidosis

A new type of therapy that 'edits' a gene in patients with a rare heart condition has been shown to be safe and effective, according to research from UCL and the Royal Free Hospital.

20 Nov 2024

More than half of all US adults are eligible for semaglutide therapy

Over 137 million US adults are eligible for semaglutide, driven by expanding indications for diabetes, weight management, and cardiovascular disease prevention.

20 Nov 2024

Study investigates impact of oxygen therapy on oxidative stress in patients with COVID-19 pneumonia

Severe COVID-19 pneumonia often requires high concentrations of oxygen, which can potentially lead to oxidative stress and lung injury.

19 Nov 2024

Study uncovers diversity of cancer-associated fibroblasts in skin cancer

A study at MedUni Vienna's Department of Dermatology provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment.

19 Nov 2024

New CAR T-cell therapy shows promise against aggressive HER2+ breast cancer

One-third of HER2-positive (HER2+) tumors express the P95HER2 protein, which associates with an aggressive form of breast cancer with a poorer prognosis. Investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Growth Factors Group, in collaboration with researchers of the Cancer Research Program of Hospital del Mar Research Institute (HMRI), Barcelona, have developed novel chimeric antigen receptor (CAR) T-cell therapy that can produce a potent antitumor response against p95HER2-expressing cells.

19 Nov 2024

From crude lysate to purity with high-precision AAV capsid measurement with Bio-Rad's new ddPCR Kit

Accurately quantify AAV capsids directly from crude lysates with Bio-Rad's new ddPCR kit—offering reliable, efficient, and precise measurement to streamline your research workflows.

From Bio-Rad Laboratories 19 Nov 2024

Global analysis reveals striking disparities in the cost and availability of cancer drugs

A recent analysis reveals striking disparities in the cost and availability of cancer drugs across different regions of the globe, with significant gaps between high- and low-income countries.

19 Nov 2024

Study: 40% of newly diagnosed heart failure patients also have atrial fibrillation

A new study by researchers at Intermountain Health in Salt Lake City finds that 40 percent of newly diagnosed heart failure patients also have atrial fibrillation – a combination of cardiac disorders that researchers found results in significantly poorer outcomes for patients.

19 Nov 2024

Adding high-dose IV vitamin C to chemotherapy can boost survival for pancreatic cancer patients

Results from a randomized phase 2 clinical trial show that adding high-dose, intravenous (IV) vitamin C to chemotherapy doubles the overall survival of patients with late-stage metastatic pancreatic cancer from eight months to 16 months.

19 Nov 2024

Stilla Technologies with Source BioScience brings advanced genomics solutions to the UK market

Stilla Technologies, a global leader in digital PCR (dPCR) solutions, has announced a strategic partnership with Source BioScience, a leading UK-based genomics service provider.

From Stilla Technologies 19 Nov 2024

Study defines three subtypes of Chiari type-1 malformation to guide treatment

Roughly 4% of the population is affected by a congenital brain malformation that has eluded researchers' efforts to find causes and treatments.

19 Nov 2024

Ultra-processed foods drive obesity and metabolic risks

Italian researchers reveal a strong link between ultra-processed foods and obesity, highlighting increased cardiometabolic risks in adults with higher UPF consumption. The findings call for urgent dietary changes to combat obesity and promote healthier lifestyles.

18 Nov 2024

Daily tablet shows promise in treating achondroplasia in children

A promising daily tablet is effective at increasing height and improving proportional limb growth in children with achondroplasia, the most common form of dwarfism, according to a new study.

18 Nov 2024

Edoxaban proves effective in preventing blood clots, stroke after heart valve surgery

Edoxaban, an oral anticoagulant, was equally or more effective than warfarin in reducing the risk of stroke and blood clots for patients after heart valve replacement surgery, according to preliminary late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Electronic nudges boost flu vaccination rates among heart attack survivors

An electronic letter, or nudge, highlighting the cardiovascular benefits of influenza vaccines improved vaccination rates among more than 2 million adults—with a greater impact on those who have had a heart attack—across three clinical trials spanning the most-recent, two consecutive influenza seasons in Denmark.

18 Nov 2024

Active feedback improves pharmacist participation in heart failure treatment

Pharmacists who received active feedback about their heart failure patients increased the frequency of their patient interactions and prescribed more heart failure medication adjustments, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Intravenous infusion of exenatide fails to reduce risks of complications in heart surgery patients

A large-scale clinical trial found that intravenous infusion of exenatide, a glucagon-like peptide-1 (GLP-1) analog medication, during heart surgeries involving bypass did not significantly reduce the risk of death, stroke or organ failure.

18 Nov 2024

Tirzepatide improves heart health and function in obese HFpEF patients

In the international SUMMIT trial, adults with heart failure preserved ejection fraction (HFpEF) and obesity taking tirzepatide for up to 3 years had a reduced combined risk of worsening heart failure events and cardiovascular death, and improved health status and physical function in comparison to participants taking placebo, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Therapy News and Research

EZH2 enzyme drives aggressive tumor growth in treatment-resistant prostate cancer

USC researchers receive $6 million to advance dry AMD treatment

CRISPR-based therapy shown to be safe, effective for people with transthyretin amyloidosis

More than half of all US adults are eligible for semaglutide therapy

Study investigates impact of oxygen therapy on oxidative stress in patients with COVID-19 pneumonia

Study uncovers diversity of cancer-associated fibroblasts in skin cancer

New CAR T-cell therapy shows promise against aggressive HER2+ breast cancer

From crude lysate to purity with high-precision AAV capsid measurement with Bio-Rad's new ddPCR Kit

Global analysis reveals striking disparities in the cost and availability of cancer drugs

Study: 40% of newly diagnosed heart failure patients also have atrial fibrillation

Adding high-dose IV vitamin C to chemotherapy can boost survival for pancreatic cancer patients

Stilla Technologies with Source BioScience brings advanced genomics solutions to the UK market

Study defines three subtypes of Chiari type-1 malformation to guide treatment

Ultra-processed foods drive obesity and metabolic risks

Daily tablet shows promise in treating achondroplasia in children

Edoxaban proves effective in preventing blood clots, stroke after heart valve surgery

Electronic nudges boost flu vaccination rates among heart attack survivors

Active feedback improves pharmacist participation in heart failure treatment

Intravenous infusion of exenatide fails to reduce risks of complications in heart surgery patients

Tirzepatide improves heart health and function in obese HFpEF patients

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