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New gene therapy shows promise for lifelong treatment of hypophosphatasia

For the last 10 years, the only effective treatment for hypophosphatasia (HPP) has been an enzyme replacement therapy that must be delivered by injection three-to-six times each week.

4 Feb 2025

New microscopy technique offers affordable way to study cancer cell metabolism

Understanding how tumors change their metabolism to resist treatments is a growing focus in cancer research.

3 Feb 2025

USC receives $6 million grant for pioneering glioblastoma gene therapy

The California Institute for Regenerative Medicine has awarded a $6 million grant to USC investigators pioneering a new first-of-its-kind genetic therapy for glioblastoma, a severe form of brain cancer.

3 Feb 2025

High-precision radiation therapy found to be safe for polymetastatic cancer

A new Phase I clinical trial from London Health Sciences Centre Research Institute (LHSCRI) has found high-precision radiation therapy is safe for use in patients with cancer that has spread to more than 10 spots in the body.

3 Feb 2025

New study confirms CAR T cell therapy does not cause secondary cancers

Within a large group of more than 700 patients treated with CAR T cell therapy, researchers found no evidence that the therapy itself caused any type of secondary cancer in the modified T cells, according to new analysis reported today in Nature Medicine from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

3 Feb 2025

Study uncovers two inhibitors to halt metaplastic breast cancer progression

A national study seeking more effective treatment for deadly metaplastic breast cancer has identified two inhibitor drugs with the potential to interrupt disease progression.

3 Feb 2025

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Laurie Adami's experience with CAR T-cell therapy highlights its potential in treating Non-Hodgkin Lymphoma, emphasizing the importance of patient advocacy.

3 Feb 2025

New targeted therapy could bring relief to people with lichen planus

Mayo Clinic researchers have identified a targeted therapy that could bring relief to people living with lichen planus, a chronic inflammatory skin condition of the skin, hair, nails, mouth and genitals.

3 Feb 2025

Prescription trends for obesity medications surge, tied to growing interest in GLP-1 drugs

Obesity medication prescriptions reached 1.5 million, driven by GLP-1 agents semaglutide and tirzepatide, as public interest influences prescription trends.

3 Feb 2025

New compound shows promise for treating psoriasis with blue light activation

Psoriasis is a chronic skin disease that manifests itself mainly with skin symptoms (dryness, itching, scaly skin, abnormal patches and plaques).

3 Feb 2025

Researchers develop model to identify tumor-fighting immune cells in lung cancer patients

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.

3 Feb 2025

Study reveals mechanism behind CAR molecule transfer in cancer therapy

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now discovered that CAR molecules can be transferred from the CAR-T cells to other T cells in the tumour microenvironment.

3 Feb 2025

Loneliness: Two types, two impacts, and what they mean for mental health

Loneliness isn't just one thing—it has two key forms: emotional loneliness (lacking deep connections) and social loneliness (lacking social networks). Recognizing these differences is crucial for mental health interventions and public policy.

2 Feb 2025

Immune system discovery could revolutionize treatment for chronic disease and cancer

A discovery about the mechanisms that enable the immune system to sustain long-term protection could revolutionize treatment for chronic disease and cancer.

31 Jan 2025

Pain coping skills training reduces pain and improves quality of life for dialysis patients

People undergoing hemodialysis treatment for kidney failure often experience chronic pain related to their condition, but it can be difficult to manage with opioid medication and other conventional treatments.

31 Jan 2025

Early side effects of radiation may increase long-term risk for prostate cancer patients

Men undergoing radiation therapy for prostate cancer who experience side effects early in treatment may face a higher risk of developing more serious long-term urinary and bowel health issues, according to a new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center.

31 Jan 2025