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New NYUCD study explores how gene expression initiated in notochord

A new study by basic science researchers in the Department of Basic Science and Craniofacial Biology at New York University College of Dentistry sought to understand how gene expression is initiated in the notochord, the evolutionary and developmental precursor of the backbone.

29 Jan 2016

Study could open door for new treatment targets to help Parkinson's disease patients walk more easily

Two secrets of one of the brain's most enigmatic regions have finally been revealed. In a pair of new studies, scientists from the Gladstone Institutes have discovered a specific neural circuit that controls walking, and they found that input to this circuit is disrupted in Parkinson's disease.

29 Jan 2016

Scientists trace one of the causes of ischemia renal failure

Every year acute renal failure affects over 13 million people and leads to 1.7 million deaths across the globe. It often develops when an insufficient supply of oxygen reaches the kidneys, a condition called ischemia.

29 Jan 2016

CNIO team uses network theory to build and study first epigenetic communication network

One of the big questions for which there is still no clear answer in biology is how, based on the four universal letters that make up DNA, it is possible to generate such different organisms as a fly or a human, or the different organs and tissues they comprise. In recent years, researchers have discovered that the system is much more complicated than was originally thought.

29 Jan 2016

LMU researchers reveal how crystalline deposits induce cell death

Crystal formation plays a defining role in the pathogenesis of a range of common diseases, such as gout and atherosclerosis. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers led by Hans-Joachim Anders have now elucidated how the insoluble deposits induce cell death.

29 Jan 2016

Researchers find how microtubules, motor proteins assemble into macroscopic networks

What bones are to bodies, the cytoskeleton is to cells. The cytoskeleton maintains cellular structure, builds appendages like flagella and, together with motor proteins, powers cellular movement, transport, and division. Microtubules are a critical component of the cytoskeleton, vital for cell division and, because of that, an excellent target for chemotherapy drugs.

29 Jan 2016

VARI-SU2C Epigenetics Dream Team supports new clinical trial that targets metastatic colorectal cancer

The first clinical trial to move forward as part of the Van Andel Research Institute-Stand Up To Cancer (VARI-SU2C) Epigenetics Dream Team will target metastatic colorectal cancer, the second leading cause of cancer deaths among men and women combined in the U.S.

29 Jan 2016

Mutation or amplification of HER2 gene may lead to lung cancer

A joint study by University of Colorado Cancer Center and Memorial Sloan Kettering Cancer Center published in the Journal of Thoracic Oncology shows two distinct causes of HER2 activation in lung cancer: mutation of the gene and amplification of the gene.

29 Jan 2016

Scientists discover epigenetic switch linked to obesity

It is well known that a predisposition to adiposity lies in our genes. A new study by researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg now shows that it is also crucial how these genes are regulated. The scientists led by Andrew Pospisilik discovered a novel regulatory, epigenetic switch, which causes individuals with identical genetic material, such as monozygotic twins, to either be lean or obese.

29 Jan 2016

Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western Reserve University faculty members have received funding to further develop emerging technologies aimed at malaria, cystic fibrosis, and sickle cell anemia.

29 Jan 2016

Study provides detailed new information about diffuse glioma

An international collaborative study has revealed detailed new information about diffuse glioma, the most common type of tumor found in some 80 percent of adult brain cancer patients, raising hopes that better understanding of these disease groups may aid improved clinical outcomes.

29 Jan 2016

Halaven (eribulin mesylate) approved for treatment of liposarcoma

The U.S. Food and Drug Administration today approved Halaven (eribulin mesylate), a type of chemotherapy, for the treatment of liposarcoma (a specific type of soft tissue sarcoma) that cannot be removed by surgery (unresectable) or is advanced (metastatic). This treatment is approved for patients who received prior chemotherapy that contained an anthracycline drug.

28 Jan 2016

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

A research team from the Department of Pharmacology and Therapeutics at Roswell Park Cancer Institute has discovered a new class of small-molecule compounds that are good candidates for development of novel targeted therapies in the treatment of leukemia and lymphoma.

28 Jan 2016

Researchers identify cells that likely give rise to Group 4 medulloblastoma

Researchers have identified the cells that likely give rise to the brain tumor subtype Group 4 medulloblastoma. The finding removes a barrier to developing more effective targeted therapies against the brain tumor's most common subtype.

28 Jan 2016

Three RIT students awarded top honors for research on bio-separation techniques

Three students from Rochester Institute of Technology were recognized for their research findings about improvements to bio-separation techniques for lab-on-a-chip medical devices. They were awarded top honors in several categories in the undergraduate and graduate research competitions at the American Institute of Chemical Engineers annual meeting and conference in November in Salt Lake City, Utah.

28 Jan 2016

Scientists pin down molecular process linked to schizophrenia origin

For the first time, researchers have managed to home in on a molecular process in the brain that contributes to the development of schizophrenia.

28 Jan 2016

New findings offer roadmap for development of novel therapies to target common brain disorders

Scientists have pinpointed the cells that are likely to trigger common brain disorders, including Alzheimer's disease, Multiple Sclerosis and intellectual disabilities.

28 Jan 2016

NTCELL stops Parkinson’s disease progression one year after treatment

Over a year after treatment all four patients who took part in Living Cell Technologies Limited’s Phase I/IIa clinical study of NTCELL® for Parkinson’s disease remain well, and at 58 weeks post-implant there are no safety concerns.

28 Jan 2016

CUMC, Iowa scientists use CRISPR to repair genetic mutation responsible for retinitis pigmentosa

Columbia University Medical Center and University of Iowa scientists have used a new gene-editing technology called CRISPR, to repair a genetic mutation responsible for retinitis pigmentosa (RP), an inherited condition that causes the retina to degrade and leads to blindness in at least 1.5 million cases worldwide.

28 Jan 2016

Using centrifugal elutriation and flow cytometry to answer biological questions: an interview with Peter Lopez

Flow Cytometry, the measurement of various cellular characteristics as they flow through a measuring apparatus, has so many applications.

From Beckman Coulter Life Sciences - Centrifugation 27 Jan 2016

Cell News and Research

New NYUCD study explores how gene expression initiated in notochord

Study could open door for new treatment targets to help Parkinson's disease patients walk more easily

Scientists trace one of the causes of ischemia renal failure

CNIO team uses network theory to build and study first epigenetic communication network

LMU researchers reveal how crystalline deposits induce cell death

Researchers find how microtubules, motor proteins assemble into macroscopic networks

VARI-SU2C Epigenetics Dream Team supports new clinical trial that targets metastatic colorectal cancer

Mutation or amplification of HER2 gene may lead to lung cancer

Scientists discover epigenetic switch linked to obesity

Three Case Western faculty members receive funding to develop new diagnostic technologies

Study provides detailed new information about diffuse glioma

Halaven (eribulin mesylate) approved for treatment of liposarcoma

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

Researchers identify cells that likely give rise to Group 4 medulloblastoma

Three RIT students awarded top honors for research on bio-separation techniques

Scientists pin down molecular process linked to schizophrenia origin

New findings offer roadmap for development of novel therapies to target common brain disorders

NTCELL stops Parkinson’s disease progression one year after treatment

CUMC, Iowa scientists use CRISPR to repair genetic mutation responsible for retinitis pigmentosa

Using centrifugal elutriation and flow cytometry to answer biological questions: an interview with Peter Lopez

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