B Cell News and Research

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Researchers create combination drug that controls both tumor growth and metastasis

Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase (sEH) inhibitor, the drug controls angiogenesis (blood vessel formation), limiting a tumor's ability to grow and spread.

14 Jul 2014

Study pinpoints molecular cause of cachexia, hints at a potential treatment

New research raises the prospect of more effective treatments for cachexia, a profound wasting of fat and muscle occurring in about half of all cancer patients, raising their risk of death, according to scientists from Dana-Farber Cancer Institute.

14 Jul 2014

New genetic programs for taking blank-slate stem cells and turning them into human blood

The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.

14 Jul 2014

Rates of testicular cancer rise in recent years among young Hispanic American men

A new analysis has found that rates of testicular cancer have been rising dramatically in recent years among young Hispanic American men, but not among their non-Hispanic counterparts.

14 Jul 2014

'Pure mass of HES molecules' explains toxicity to renal tubule cells

The increased risk of kidney injury related to the use of hydroxyethyl starch (HES) in resuscitation fluids reflects the mass of HES molecules, according to a report in Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

14 Jul 2014

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Scientists at the Helmholtz Zentrum München, the Ludwig-Maximilians University of Munich (LMU) and the Technische Universität München (TUM) have moved an important step closer to understanding molecular mechanisms of autoimmune diseases.

14 Jul 2014

Eye exam for beta-amyloid correlates with levels in brain, detects people with Alzheimer's

A decreased ability to identify odors might indicate the development of cognitive impairment and Alzheimer's disease, while examinations of the eye could indicate the build-up of beta-amyloid, a protein associated with Alzheimer's, in the brain, according to the results of four research trials reported today at the Alzheimer's Association International Conference- 2014 (AAIC- 2014) in Copenhagen.

14 Jul 2014

New mouse model supports transplantation of human blood stem cells without need for irradiation

A novel mouse model allows for the transplantation of human blood-forming stem cells without the need for irradiation therapy.For many years scientists have been trying to unravel mechanisms that guide function and differentiation of blood stem cells, those cells that generate all blood cells including our immune system.

11 Jul 2014

Astrocytes play role in forming inhibitory synapses

Rio de Janeiro, Brazil- In the brains of all vertebrates, information is transmitted through synapses, a mechanism that allows an electric or chemical signal to be passed from one brain cell to another.

11 Jul 2014

Researchers examine why antioxidant actually do more harm than good

For decades, health-conscious people around the globe have taken antioxidant supplements and eaten foods rich in antioxidants, figuring this was one of the paths to good health and a long life.

11 Jul 2014

BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

BrightFocus Foundation, a nonprofit organization funding cutting-edge, innovative research on Alzheimer's disease and the vision diseases of glaucoma and macular degeneration, today announced the recipients of new research grant awards, offered to 55 scientists in 19 U.S. states, the District of Columbia, and five foreign countries.

11 Jul 2014

New chemical compound protects against blindness and diabetes in animals

In a new study led by UC San Francisco scientists, a chemical compound designed to precisely target part of a crucial cellular quality-control network provided significant protection, in rats and mice, against degenerative forms of blindness and diabetes.

11 Jul 2014

Bacterial respiratory tract colonization before catching influenza may protect against severe disease

Many studies have shown that more severe illness and even death are likely to result if you develop a secondary respiratory infection after developing influenza. Now, however, a team of researchers based at The Wistar Institute has determined that if you reverse the order of infection, the bacteria Streptococcus pneumoniae (often called pneumococcus) may actually protect against a bad case of the flu.

11 Jul 2014

Baxter International acquires drug candidate developed to treat sickle cell disease

A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience business.

11 Jul 2014

New approach for developing personalized gene therapies to treat retinitis pigmentosa

Columbia University Medical Center researchers have created a way to develop personalized gene therapies for patients with retinitis pigmentosa (RP), a leading cause of vision loss.

11 Jul 2014

AZD3965 drug could prove useful in treating small cell lung cancer

Manchester scientists have shown that a new drug could prove useful in treating small cell lung cancer - the most aggressive form of lung cancer.

From The University of Manchester 10 Jul 2014

New knowledge may expand treatments for patients with lung cancer

Studying the most common type of lung cancer, researchers have uncovered mutations in a cell-signaling pathway that plays a role in forming tumors.

10 Jul 2014

New pathway to disabling disease: blocking bacteria's access to iron in the body

In an era of increasing concern about the prevalence of antibiotic-resistant illness, Case Western Reserve researchers have identified a promising new pathway to disabling disease: blocking bacteria's access to iron in the body.

10 Jul 2014

Penn receives $8 million grant from NCI to study effects of PDT

Researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Roswell Park Cancer Institute have received an $8 million grant from the National Cancer Institute (NCI) to study the effects of photodynamic light therapy (PDT) in patients with malignant pleural mesothelioma, a rare, aggressive and deadly cancer that most often manifests itself in the lining of the lungs and is caused almost exclusively by exposure to asbestos.

10 Jul 2014

New drug could prove useful in treating small cell lung cancer

Manchester scientists have shown that a new drug could prove useful in treating small cell lung cancer - the most aggressive form of lung cancer.

From The University of Manchester 10 Jul 2014

B Cell News and Research

Researchers create combination drug that controls both tumor growth and metastasis

Study pinpoints molecular cause of cachexia, hints at a potential treatment

New genetic programs for taking blank-slate stem cells and turning them into human blood

Rates of testicular cancer rise in recent years among young Hispanic American men

'Pure mass of HES molecules' explains toxicity to renal tubule cells

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Eye exam for beta-amyloid correlates with levels in brain, detects people with Alzheimer's

New mouse model supports transplantation of human blood stem cells without need for irradiation

Astrocytes play role in forming inhibitory synapses

Researchers examine why antioxidant actually do more harm than good

BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

New chemical compound protects against blindness and diabetes in animals

Bacterial respiratory tract colonization before catching influenza may protect against severe disease

Baxter International acquires drug candidate developed to treat sickle cell disease

New approach for developing personalized gene therapies to treat retinitis pigmentosa

AZD3965 drug could prove useful in treating small cell lung cancer

New knowledge may expand treatments for patients with lung cancer

New pathway to disabling disease: blocking bacteria's access to iron in the body

Penn receives $8 million grant from NCI to study effects of PDT

New drug could prove useful in treating small cell lung cancer

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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