B Cell News and Research

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Study reveals effect of 3-n-butylphthalide on chronic ischemic stroke

The pathogenesis of vascular dementia induced by chronic cerebral ischemia is complex, mainly consisting of energy metabolism disorder, oxidative stress injury, neuronal apoptotic cell death and cholinergic nerve dysfunction.

10 Jul 2014

NANOG gene linked to tumours derived from stratified epithelia

Scientists from the Spanish National Cancer Research Centre (CNIO) have discovered that NANOG, an essential gene for embryonic stem cells, also regulates cell division in stratified epithelia-those that form part of the epidermis of the skin or cover the oesophagus or the vagina-in adult organisms.

10 Jul 2014

Research into cell metabolism could open new therapeutic avenues for diabetes, cancer

More scientific research into the metabolism of stromal support cells and immune cells - and the role of the metabolism of these cell types in the development of diseases - could open new therapeutic avenues for diabetes, inflammatory conditions and cancer. That was the conclusion of a review article by scientists from VIB and KU Leuven in the leading journal Nature.

10 Jul 2014

TCGA finds novel mutations in key cancer-causing pathway in lung adenocarcinoma

Researchers from The Cancer Genome Atlas Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer.

10 Jul 2014

Research uncovers how complex protein pivotal in cancer development is activated

New research has uncovered how a complex protein pivotal in the development of cancer, viral infection and autoimmune diseases is activated.

10 Jul 2014

Immune marker predicts infection risk in critically ill children with traumatic injuries

Researchers studying critically ill children with traumatic injuries have identified an immune marker that predicts which patients are likely to develop a hospital-acquired infection.

10 Jul 2014

Rockefeller scientists identify protein that makes breast cancer cells more likely to metastasize

Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists at Rockefeller University have identified a protein that makes breast cancer cells more likely to metastasize.

10 Jul 2014

NIH funds Phase II 90-subject pediatric clinical trial at UCLA

NeuroSigma, Inc., a California-based life sciences company focused on commercialization of its non-invasive Monarch eTNS System for the treatment of neurological and neuropsychiatric disorders, today announced that the U.S. National Institutes of Health (NIH) has awarded UCLA a grant that funds a Phase II 90-subject pediatric clinical trial at the University of California, Los Angeles focused on the treatment of Attention Deficit Hyperactivity Disorder (ADHD) with NeuroSigma's external trigeminal nerve stimulation (eTNS) System.

10 Jul 2014

Researchers receive $8 million NCI grant to study effects of PDT in patients with mesothelioma

Researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Roswell Park Cancer Institute have received an $8 million grant from the National Cancer Institute to study the effects of photodynamic light therapy (PDT) in patients with malignant pleural mesothelioma, a rare, aggressive and deadly cancer that most often manifests itself in the lining of the lungs and is caused almost exclusively by exposure to asbestos.

10 Jul 2014

Astellas seeks isavuconazole approval from FDA for treatment of life-threatening fungal infections

Astellas today announced it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration seeking approval for isavuconazole for the treatment of invasive aspergillosis and invasive mucormycosis (also known as zygomycosis), life-threatening fungal infections predominantly occurring in immunocompromised patients.

9 Jul 2014

Lung cancer and melanoma funders form first-ever research collaboration

LUNGevity Foundation today announced a partnership with the Lung Cancer Research Foundation and Melanoma Research Alliance to co-fund new innovative research on PD-1 inhibitor treatment options for both non-small cell lung cancer (NSCLC) and metastatic melanoma (MM) patients with brain metastases.

9 Jul 2014

Study: Children on dairy farms run much lower risk of developing allergies

The occurrence of allergic diseases has risen dramatically in Western societies. One frequently cited reason is that children are less exposed to microorganisms and have fewer infections than previous generations, thereby delaying maturation of the immune system.

9 Jul 2014

Telemedicine could improve quality of life of patients with chronic liver diseases

Although telemedicine could improve the quality of life of patients with chronic liver diseases, viable home care systems are still lacking. Scientists working on the EU-project "d-LIVER" mean to remedy this situation. Initial results have now been released.

9 Jul 2014

Scientists find a new strategy for brain cancer treatment

Scientists at the Montreal Neurological Institute and Hospital, McGill University and McGill University Health Centre have shown that a member of the protein family known as SUMO (small ubiquitin-like modifier) is a key to why tumour cells multiply uncontrollably, especially in the case of glioblastoma. T

9 Jul 2014

New gene therapy may be effective for fighting fungal infections in cancer patients

Sleeping Beauty and fungal infections - not two items one would normally associate together, but for immunocompromised cancer patients they may prove to be a helpful combination.

9 Jul 2014

Scientists reveal structure of protein complex involved in liver and colon cancers

A group of scientists from Spain, the UK and the United States has revealed the structure of a protein complex involved in liver and colon cancers. Both of these types of cancer are of significant social and clinical relevance as in 2012 alone, liver cancer was responsible for the second highest mortality rate worldwide, with colon cancer appearing third in the list.

9 Jul 2014

New research unit to uncover multi-drug resistant bacteria in hospitals

Multi-drug resistant bacteria have increased dramatically in hospitals in recent years and present immense challenges to staff and patients, often with fatal results.

8 Jul 2014

Genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma

Two genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma (iCCA), the second most common form of liver cancer, according to a research published in the July issue of the journal Nature.

8 Jul 2014

Skin cells possess olfactory receptor for sandalwood scent

Skin cells possess an olfactory receptor for sandalwood scent, as researchers at the Ruhr-Universit-t Bochum have discovered.

8 Jul 2014

Researchers identify new genes that likely contribute to asthma

In a study published yesterday in the scientific journal Nature Immunology, a group at the La Jolla Institute (LJI) led by Pandurangan Vijayanand, Ph.D. identify new genes that likely contribute to asthma, a disease that currently affects over 200 million people world wide.

8 Jul 2014

B Cell News and Research

Study reveals effect of 3-n-butylphthalide on chronic ischemic stroke

NANOG gene linked to tumours derived from stratified epithelia

Research into cell metabolism could open new therapeutic avenues for diabetes, cancer

TCGA finds novel mutations in key cancer-causing pathway in lung adenocarcinoma

Research uncovers how complex protein pivotal in cancer development is activated

Immune marker predicts infection risk in critically ill children with traumatic injuries

Rockefeller scientists identify protein that makes breast cancer cells more likely to metastasize

NIH funds Phase II 90-subject pediatric clinical trial at UCLA

Researchers receive $8 million NCI grant to study effects of PDT in patients with mesothelioma

Astellas seeks isavuconazole approval from FDA for treatment of life-threatening fungal infections

Lung cancer and melanoma funders form first-ever research collaboration

Study: Children on dairy farms run much lower risk of developing allergies

Telemedicine could improve quality of life of patients with chronic liver diseases

Scientists find a new strategy for brain cancer treatment

New gene therapy may be effective for fighting fungal infections in cancer patients

Scientists reveal structure of protein complex involved in liver and colon cancers

New research unit to uncover multi-drug resistant bacteria in hospitals

Genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma

Skin cells possess olfactory receptor for sandalwood scent

Researchers identify new genes that likely contribute to asthma

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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