DNA Damage News and Research

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How conversion between different types of cell death contributes to disease

Researchers elucidate the role of cell death in the pathogenesis of different diseases.

10 Aug 2023

The impact of epigenetic features on breast cancer treatment and outcomes

The impact of epigenetic features on breast cancer treatment and outcomes.

9 Aug 2023

NCI funds study to investigate the underlying cellular mechanisms that drive ER+ breast cancer

The National Cancer Institute (NCI) has awarded a 5-year, $2.7 million grant to researchers at Sanford Burnham Prebys to investigate and elucidate the underlying cellular mechanisms that drive the most common form of breast cancer.

7 Aug 2023

Exploring human aging via elephant research

Indiana University researcher Daniella Chusyd is studying human aging in an unlikely way: through elephants.

4 Aug 2023

New PCNA inhibitor AOH1996 shows selective cancer cell killings and tumor suppression potential

Study described a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) that selectively kills cancer cells.

4 Aug 2023

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Researchers described the dual role of cell cycle and apoptosis regulator 2 (CCAR2) in cancer progression as a tumor suppressor and promoter.

4 Aug 2023

Study uncovers the science behind the body's tanning process after leaving the beach

Beachgoers are familiar with the experience of spending hours in the sun, going home, and noticing only hours later that their skin has changed color.

3 Aug 2023

The effects of oxidative stress on women’s fertility

Scientists review existing literature to assess the relationship between oxidative stress and female infertility.

1 Aug 2023

Two new compounds can block cancer cell’s escape route

Cancer cells are capable of escaping chemotherapy and radiotherapy by activating a signaling pathway that prevents them from dying.

27 Jul 2023

Combination therapy shows promise in treating advanced ER+ breast cancer

Advanced estrogen receptor-positive (ER+) breast cancer can be especially difficult to treat. A new study by researchers at Dartmouth Cancer Center led by Todd W. Miller, PhD, shows promise in using a combination of estrogen and a PARP inhibitor (a drug that suppresses DNA damage repair), to treat this type of cancer.

13 Jul 2023

New study reveals how lung tumors develop drug resistance

Cancer therapies that target specific genetic abnormalities in tumors have revolutionized treatment possibilities over the past two decades.

13 Jul 2023

Overdosed gene on chromosome 21 accelerates aging in people with Down's syndrome

An overdosed gene on chromosome 21 causes people with Down's Syndrome to age faster than the general population.

12 Jul 2023

Smoking and HPV found to increase risk of head and neck cancer

Tobacco smoking and human papillomavirus (HPV) are both well-known risk factors for head and neck cancer, but there is ample evidence to show they can interact to increase still further the risk of contracting the disease, according to a study by scientists at the University of São Paulo (USP) in Brazil and the University of Chile.

3 Jul 2023

Cyanotriazole compounds can selectively and rapidly kill trypanosome parasites, study shows

Cyanotriazole compounds are fast-acting topoisomerase II poisons that can selectively and rapidly kill trypanosome parasites that cause Chagas disease and African sleeping sickness, according to a new study.

29 Jun 2023

Is there an association between muscle-building supplements and DNA damage in resistance training practitioners?

A recent study investigated whether muscle-building supplements are associated with DNA damage in individuals practicing resistance training.

27 Jun 2023

New study warns of dangers of gene editing in human embryos

Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA.

26 Jun 2023

Histone acetyltransferases: Promising targets for cancer treatment

Announcing a new publication for Acta Materia Medica journal. Histone lysine acylation is a major class of histone post-translational modifications involved in essential biological activities, such as transcriptional regulation, DNA-damage, a repairnd cell-cycle progression.

25 Jun 2023

DNA Damage News and Research

How conversion between different types of cell death contributes to disease

The impact of epigenetic features on breast cancer treatment and outcomes

NCI funds study to investigate the underlying cellular mechanisms that drive ER+ breast cancer

Exploring human aging via elephant research

New PCNA inhibitor AOH1996 shows selective cancer cell killings and tumor suppression potential

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Study uncovers the science behind the body's tanning process after leaving the beach

The effects of oxidative stress on women’s fertility

Two new compounds can block cancer cell’s escape route

Combination therapy shows promise in treating advanced ER+ breast cancer

New study reveals how lung tumors develop drug resistance

Overdosed gene on chromosome 21 accelerates aging in people with Down's syndrome

Smoking and HPV found to increase risk of head and neck cancer

Cyanotriazole compounds can selectively and rapidly kill trypanosome parasites, study shows

Is there an association between muscle-building supplements and DNA damage in resistance training practitioners?

New study warns of dangers of gene editing in human embryos

Histone acetyltransferases: Promising targets for cancer treatment

New embryonic cell type that self-destructs to protect the developing fetus discovered

Does taurine deficiency speed up aging?

Study reveals impressive skin benefits of blueberries

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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