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USC scientists target brain inflammation to prevent Alzheimer's disease

An interdisciplinary team at the USC Center for Personalized Brain Health (CPBH) is targeting a family of enzymes that can increase the risk of inflammation in the brains of people with the APOE4 gene variation-the most significant genetic risk factor for late-onset Alzheimer's-as a way to prevent the disease.

2 Jul 2026

Widely used pandemic pharmaceuticals harm marine aquatic ecosystems

A new study published in New Contaminants suggests that several drugs widely used during the COVID-19 pandemic can be toxic to marine organisms, even at relatively low concentrations.

2 Jul 2026

Paracetamol during pregnancy does not raise autism or ADHD risk

A sibling-matched study finds no link between prenatal paracetamol use and autism or ADHD, reassuring its safety when clinically indicated during pregnancy.

2 Jul 2026

Targeted therapy doubles progression-free survival in rare bile duct cancer

Results of the ongoing eNRGy trial, a single-arm, multicenter, global phase 2 clinical trial evaluating zenocutuzumab in solid tumors positive for Neuregulin 1 (NRG1) gene fusions, reported manageable side effects and clinically meaningful efficacy – including a near doubling of progression-free survival compared to expectations with standard of care – in previously treated patients with advanced NRG1-positive cholangiocarcinoma.

2 Jul 2026

Smart prodrug targets Alzheimer's disease using hydrogen peroxide signals

A substance that worsens dementia has become a "switch" that initiates treatment. KAIST researchers have developed a new therapeutic approach that uses hydrogen peroxide (H₂O₂), a reactive oxygen species that damages cells and increases in the brains of patients with Alzheimer's disease, to activate a drug selectively in diseased brain tissue.

1 Jul 2026

Engineered CAR T cells show promise against myeloproliferative neoplasms

A new form of CAR T cell therapy has been designed to find and destroy the cancer-driving stem cells responsible for a group of blood cancers known as myeloproliferative neoplasms (MPNs), while leaving healthy blood cells unharmed, in new research led by UCL and University of Oxford researchers.

1 Jul 2026

UC San Diego study reveals genetic causes of rare neuromuscular disorders

Scientists at the University of California San Diego have uncovered how genetic mutations cause a rare group of inherited neuromuscular disorders and identified promising new strategies to correct them, including a potential new use for an existing antidepressant.

1 Jul 2026

Fatty liver disease fuels aggressive metastatic colorectal cancer spread

Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most aggressive form of metastatic colorectal cancer.

1 Jul 2026

German study identifies therapeutic Achilles' heel for advanced colorectal cancer

A team led by researchers from the German Cancer Research Center (DKFZ) and the HI-STEM* Stem Cell Institute has discovered a promising new approach to treating advanced colorectal cancer.

1 Jul 2026

EULAR project reveals large disparities in European rheumatology care

Rheumatic and musculoskeletal diseases (RMD) are responsible for significant disability, and result in long-term work loss or early retirement.

1 Jul 2026

Alzheimer’s disease biomarkers predict rapid cognitive decline in very old adults

Cognitive decline in very old adults has been considered for decades to be an almost inevitable consequence of aging.

1 Jul 2026

New bacterial enzyme blueprint could accelerate cancer treatment development

A team of researchers at the University of Warwick and Monash University has solved a puzzle that's stumped drug developers for decades: how bacteria naturally create multiple versions of powerful cancer therapies.

1 Jul 2026

Cancer's biggest treatment challenge may be getting solved 250 miles above Earth

For more than two decades, precision oncology has been promoted as the future of cancer treatment, matching therapies to the unique biology of a patient's tumor.

1 Jul 2026

New national program targeting harmful and unnecessary medicine use in Australia

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1 Jul 2026

Study links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity care

A US electronic health record study found that adults with obesity who started semaglutide or tirzepatide had lower recorded hazards of anxiety and depression than matched patients using naltrexone-bupropion. However, among adults without type 2 diabetes, tirzepatide was linked to higher recorded hazards of anxiety and insomnia than semaglutide, underscoring the need for cautious monitoring.

1 Jul 2026

Melatonin may safely reduce chronic musculoskeletal pain, study finds

A sleep supplement widely used to treat insomnia could help reduce reliance on some of the most common and potentially harmful pain medications, new research from the University of Sydney suggests.

30 Jun 2026

New structural insights overturn old assumptions about malaria entry

For nearly half a century, scientists have known that malaria parasites force their way into human red blood cells through a ring-shaped structure called the moving junction.

30 Jun 2026

Highly-sensitive blood test detects hidden traces of pancreatic cancer

Northwestern Medicine scientists have demonstrated that a highly sensitive blood test can detect traces of pancreatic cancer missed by standard testing, potentially helping physicians identify patients whose disease is more likely to return even when scans appear reassuring.

30 Jun 2026

UCD professor wins ERC grant for pediatric growth disorder research

Professor Niamh Nowlan of University College Dublin (UCD) has been awarded a European Research Council (ERC) Proof of Concept Grant for research with the potential to enable new treatments for a broad range of paediatric growth disorders.

30 Jun 2026

Strong chest and back muscles linked to lower risk of a heart attack

People with strong muscles in their chest and back are less likely to have heart attacks, according to analysis of heart scans using artificial intelligence which was part-funded by the British Heart Foundation and led by the University of Edinburgh.

30 Jun 2026