Glucose Metabolism News and Research

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Study offers insight into how female Viagra affects the brain

As the drug touted as "the female Viagra" comes to market, researchers at the University of Wisconsin-Madison are learning more about how the drug, called flibanserin, affects the brain.

13 Dec 2015

RV glucose metabolism changes associated with RV function

The rate of myocardium glucose utilisation in the right ventricle correlates with its function and could be used to monitor treatment effects in patients with pulmonary arterial hypertension, findings indicate.

11 Dec 2015

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. In their report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital-based research team describes finding how these microRNAs could reduce the expression of proteins playing key roles in the generation of beneficial HDL cholesterol, the disposal of artery-clogging LDL cholesterol, control of triglyceride levels and other risk factors of cardiovascular disease.

27 Oct 2015

Melatonin and the circadian rhythm: an interview with Professor Kennaway, University of Adelaide

The production of melatonin is controlled by a part of the brain called the suprachiasmatic nucleus (SCN) and its timing fine-tuned by our exposure to light during the morning.

20 Oct 2015

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Ember Therapeutics, Inc., a privately held, New York-based biopharmaceutical company that is developing targeted therapies for osteoarthritis, kidney fibrosis, and other indications using Bone Morphogenetic Protein (BMP)-7, announced today initial results from the Phase II(a) trial of local BMP-7 administration in patients with moderate osteoarthritis of the knee.

20 Oct 2015

UVA researchers receive $1.9 million NIH grant to prevent heart failure

Could your heart get hooked on blood sugar? Researchers at the University of Virginia School of Medicine think so, and they will determine if blocking that addiction could prevent enlargement of the heart that can lead to deadly heart failure.

14 Oct 2015

Novo Nordisk announces FDA approval of Tresiba (insulin degludec injection) for diabetes treatment

Novo Nordisk, a world leader in diabetes care, today announced that the U.S. Food and Drug Administration approved the new drug application for Tresiba (insulin degludec injection), a once-daily, long-acting basal insulin. Tresiba is indicated for use alone, or in combination with oral antidiabetic medicines or bolus insulin, and is approved for glycemic control in adults with type 1 and type 2 diabetes. Tresiba provides a long duration of action beyond 42 hours.

From Novo Nordisk 26 Sep 2015

Cancer-causing gene disrupts internal rhythm, metabolic pathways in cancer cells

Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Postdoctoral fellow Brian Altman, PhD, and doctoral student Annie Hsieh, MD, both from the lab of senior author Chi Van Dang, MD, PhD, director Abramson Cancer Center, study body clock proteins associated with cancer cells.

18 Sep 2015

Treating cancer cells with quizartinib inhibits key metabolic pathway, activates macroautophagy

A study published in The Journal of Cell Biology describes a way to force cancer cells to destroy a key metabolic enzyme they need to survive.

1 Sep 2015

Drinking coffee increases risk of cardiovascular events in young adults with mild hypertension

Coffee drinking is associated with increased risk of cardiovascular events (mainly heart attacks) in young adults (18-45) with mild hypertension, according to research presented at ESC Congress today by Dr Lucio Mos, a cardiologist at Hospital of San Daniele del Friuli in Udine, Italy.

29 Aug 2015

Fish oil diet modifies gut bacteria to boost health

Diets rich in fish oil versus diets rich in lard produce very different bacteria in the guts of mice, reports a study from Sahlgrenska Academy published in Cell Metabolism. The researchers transferred these microbes into other mice to see how they affected health. The results suggest that gut bacteria share some of the responsibility for the beneficial effects of fish oil and the harmful effects of lard.

29 Aug 2015

UH research points to promising target in treatment of pancreatic cancer

Pancreatic cancer is extremely deadly and often has a poor prognosis. Ranked as the fourth deadliest cancer in the U.S. and poised to move up within the next few years, pancreatic cancer is very difficult to detect in its early stages. Seldom diagnosed early and typically spreading rapidly, the disease has no effective treatment once it advances.

26 Aug 2015

Muscle mass appears to ward off bad cardiovascular effects of obesity

Even without losing fat, more muscle appears to go a long way in fighting off the bad cardiovascular effects of obesity. That emerging evidence has scientists looking hard for new targets to uncouple the unhealthy relationship between fat and cardiovascular disease.

18 Aug 2015

New Tel Aviv University study reveals impact of skipping breakfast on the health of diabetics

More and more Americans on-the-go are skipping the "most important meal of the day," not eating until lunch. This tendency to miss breakfast has already been linked to the growing epidemic of obesity and cardiovascular problems in the US -- and it may put the health of diabetics at risk as well.

29 Jul 2015

UT Southwestern researchers find potential therapy to treat diabetes, nonalcoholic fatty liver disease

Reducing high concentrations of a fatty molecule that is commonly found in people with diabetes and nonalcoholic fatty liver disease rapidly improves insulin sensitivity, UT Southwestern Medical Center diabetes researchers have found.

17 Jul 2015

Alzheimer's disease may be 'at work' years ahead of actual symptoms, say IU researchers

The best-known genetic variant linked to Alzheimer's disease may be "at work" promoting deposits of plaque in the brain long before any symptoms of the disease can be measured on tests, according to a national research study led by Indiana University School of Medicine investigators.

14 Jul 2015

Study finds gene linked to age-related obesity, diabetes

Practically everyone gets fatter as they get older, but some people can blame their genes for the extra padding. Researchers have shown that two different mutations in a gene called ankyrin-B cause cells to suck up glucose faster than normal, fattening them up and eventually triggering the type of diabetes linked to obesity.

14 Jul 2015

La Jolla Institute researchers identify molecular pathway that maintains Treg cells' function

Regulatory T cells (Treg cells) are part of the system of checks and balances that prevents the immune response from going overboard and causing autoimmune disease. Although critically important for shaping the immune response and maintaining self-tolerance, how they hold on to their immune-suppressive powers had remained unclear.

17 Jun 2015

New therapy for osteoporosis may be in the pipeline

Researchers from The Scripps Research Institute (TSRI), Florida, have reported a novel therapeutic approach that could promote the formation of new bone cells in people suffering from bone loss.

12 Jun 2015

Dexcom® announces follow App is now available for Android devices

Continuous glucose monitoring is considered the most significant breakthrough in diabetes management in the past 40 years...

4 Jun 2015