Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Largest hepatitis-C U.S. study defines optimal therapy

Final results of the WIN-R trial,[1] the largest hepatitis C study conducted in U.S. patients, showed that weight-based REBETOL (ribavirin, USP) in combination therapy with PEG-INTRON (peginterferon alfa-2b) achieved significantly higher rates of sustained virologic response (SVR)[2] and lower rates of relapse compared to the combination therapy using a flat dose of ribavirin.

14 Nov 2005

Interferon combined with ribavirin treatment is effective for children with chronic Hepatitis C virus

Nearly half of 118 children with chronic Hepatitis C virus (HCV) treated with a combination of interferon-alpha-2b and an optimized dose of ribavirin achieved sustained viral response, and side effects were generally mild.

3 Nov 2005

Treating Irritable Bowel Syndrome with constipation may have a significant impact on absenteeism

"IBS symptoms of abdominal pain or discomfort, bloating and constipation are associated with impaired quality of life and are the second most common cause of work-related absenteeism," according to Dr. Nigel Flook of the University of Alberta.

1 Nov 2005

Silent reflux may be the cause of sleep disturbances in patients with unexplained sleep disorders

Patients with sleep complaints but no heartburn symptoms suffered episodes of nighttime acid reflux according to research presented at the 70th Annual Scientific Meeting of the American College of Gastroenterology.

1 Nov 2005

Gatorade appears effective in correcting dehydration and improving bowel symptoms

A double-blind trial of oral rehydration solutions for children with diarrhea and vomiting related to acute viral gastroenteritis found that Gatorade is as effective as Pedialyte in correcting dehydration and improving bowel symptoms.

1 Nov 2005

Link between the act of lying and a significant increase in gastric arrhythmia

A new study suggests that changes in gastric physiology perform better than standard polygraph methods in distinguishing between lying and telling the truth.

1 Nov 2005

Women more at risk for colorectal cancer

A new study of gender and risk factors for colorectal cancer reveals that while both tobacco and alcohol increase risk for colorectal cancer, women who smoke are at higher risk.

1 Nov 2005

Ibuprofen and naproxen combined with aspirin increase risk of gastrointestinal complications

Patients who combine the common over-the counter pain medications ibuprofen and naproxen with aspirin have a risk of gastrointestinal complications including ulcers, perforations and bleeding that is two to three times greater than patients who take these medications but do not combine them with aspirin.

1 Nov 2005

Study shows impact of birth order on maternal feelings of excessive concern

New research presented at the 70th Annual Scientific Meeting of the American College of Gastroenterology suggests that birth order impacts child perceptions of maternal solicitousness toward GI symptoms, particularly in families where the mother has Irritable Bowel Syndrome (IBS).

1 Nov 2005

Diabetics are significantly more likely to have colon cancer

Researchers at the Medical University of South Carolina reported results from a large cross-sectional analysis assessing the risk of colon cancer among patients with diabetes at the 70th Annual Scientific Meeting of the American College of Gastroenterology.

1 Nov 2005

Regular use of ibuprofen may increase gastrointestinal bleeding

People who take high doses of ibuprofen on a regular basis are three times more likely to experience gastrointestinal (GI) bleeding than those who do not take painkillers.

1 Nov 2005

Colon cancer hits blacks at a younger age

In a review of medical records researchers say that African-Americans are more susceptible to colon cancer at an earlier age than whites.

31 Oct 2005

When it comes to telling lies it's the stomach not the heart which is the giveaway

According to a new study it is suggested that it is the stomach rather than the heart that offers greater lie detection accuracy.

31 Oct 2005

State budget cuts lead to decline in care by private practice physicians

In a study of access to specialty healthcare by the uninsured and publicly insured in New Haven, Yale researchers found that recent state budget cuts, out-of-date provider rates and other policy changes had caused a decline in care by private practice physicians.

25 Oct 2005

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

A new study from the University of North Carolina at Chapel Hill School of Medicine may have found a way to identify those at greatest risk, thereby allowing doctors to decide who should receive treatment that could save the transplanted organ. The new findings appear in the October issue of the journal Liver Transplantation.

9 Oct 2005

Potential biomarker that could be used to predict who might develop hepatic fibrosis

Two new studies on Hepatitis C (HCV) patients who underwent liver transplants examined a potential biomarker that could be used to predict who might develop hepatic fibrosis, a formation of scar-like tissue that can lead to cirrhosis.

3 Oct 2005

Physical activity may reduce gastrointestinal symptoms in people who are obese

In a study published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, researchers found that a high body mass index (BMI) and lack of physical activity were associated with an increase in GI symptoms such as stomach pain, diarrhea, constipation and irritable bowel syndrome (IBS).

3 Oct 2005

Irritable Bowel Syndrome (IBS) treatment using hypnotherapy

Up to eight million people in Britain suffer from IBS, with symptoms including diarrhoea, pain and bloating. The condition can seriously affect sufferers' quality of life and finding treatment can be difficult, leading many doctors to feel they can do little to help.

From The University of Manchester 27 Sep 2005

Patients with irritable bowel syndrome use over 50 percent more health resources than people without the disorder

Even though there are definitive guidelines to diagnose IBS through simple blood tests, many IBS patients have additional procedures and surgeries that rarely result in relief or any additional diagnostic findings.

27 Sep 2005

Gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease

Their research, led by Professor Alastair Watson in the University's Faculty of Medicine, could have important implications for the treatment of patients with diseases like Crohn's - an inflammatory bowel disorder that causes severe ulceration in the intestine, leading to pain, bleeding and diarrhoea.

20 Sep 2005

Gastroenterology News and Research

Further Reading

Largest hepatitis-C U.S. study defines optimal therapy

Interferon combined with ribavirin treatment is effective for children with chronic Hepatitis C virus

Treating Irritable Bowel Syndrome with constipation may have a significant impact on absenteeism

Silent reflux may be the cause of sleep disturbances in patients with unexplained sleep disorders

Gatorade appears effective in correcting dehydration and improving bowel symptoms

Link between the act of lying and a significant increase in gastric arrhythmia

Women more at risk for colorectal cancer

Ibuprofen and naproxen combined with aspirin increase risk of gastrointestinal complications

Study shows impact of birth order on maternal feelings of excessive concern

Diabetics are significantly more likely to have colon cancer

Regular use of ibuprofen may increase gastrointestinal bleeding

Colon cancer hits blacks at a younger age

When it comes to telling lies it's the stomach not the heart which is the giveaway

State budget cuts lead to decline in care by private practice physicians

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

Potential biomarker that could be used to predict who might develop hepatic fibrosis

Physical activity may reduce gastrointestinal symptoms in people who are obese

Irritable Bowel Syndrome (IBS) treatment using hypnotherapy

Patients with irritable bowel syndrome use over 50 percent more health resources than people without the disorder

Gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease

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