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New insights into the interplay between prions and TDP-43 in neurodegenerative pathology

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death.

4 Dec 2023

Neuroimaging and network modeling tools shed light on Alzheimer's disease in animal models

Indiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools - previously developed to analyze brains of patients in the clinic - to investigate Alzheimer's disease progression in preclinical animal models.

4 Dec 2023

MU researchers unveil the immune system's secret weapon against lung cancer

As one of the most insidious diseases in the world, cancer has few treatments that work to eradicate it completely.

4 Dec 2023

MAbID offers a deep dive into chromatin dynamics and gene regulation

Researchers from the group of Jop Kind developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease.

4 Dec 2023

UCLA studies unravel metabolic pathways in prostate cancer treatment

Two new studies led by researchers from the UCLA Jonsson Comprehensive Cancer Center give insight into how cells use energy to influence the way prostate tumors survive and grow - advancements that can help explain why some prostate cancers become resistant to hormone therapy, the most commonly used treatment for men with advanced stages of the disease.

4 Dec 2023

Study reveals how maternal diabetes affects birth defects at the single-cell level

The mechanisms by which maternal diabetes mellitus contributes to congenital abnormalities in the fetus.

4 Dec 2023

UK Biobank unveils world's largest genetic data set

In a momentous landmark for medical research, UK Biobank has today [Thursday 30 November] unveiled incredible new data from whole genome sequencing of its half a million participants.

4 Dec 2023

CHOP researchers unlock 3D structure of crucial protein for cancer therapy

Chimeric Antigen Receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-treat cancers, as they have the ability to deliver targeted therapies that can kill tumor cells.

1 Dec 2023

Scientists warn of potential pitfalls when using the Cre-LoxP system in cancer research

A new editorial paper was published in Oncoscience (Volume 10) on November 14, 2023, entitled, "Be mindful of potential pitfalls when using the Cre-LoxP system in cancer research."

1 Dec 2023

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Researchers at UC Davis Comprehensive Cancer Center have shown that inhibiting a specific protein using gene therapy can shrink hepatocellular carcinoma (HCC) in mice.

30 Nov 2023

Extra gene copies drive evolutionary innovation in pitcher plants

Possessing more than two complete sets of chromosomes can be a hindrance to long-term survival of a plant lineage, yet scientists are also finding evidence it's likely behind some evolutionary innovation.

30 Nov 2023

Scientists uncover cellular cause of heart defects in babies born to women with diabetes

When women with diabetes become pregnant, they face not only the typical challenges of pregnancy and impending parenthood, but also a scary statistic: they're five times more likely to have a baby with a congenital heart defect.

30 Nov 2023

New study provides convincing evidence of the essential role of cylicins in sperm development and fertility

Researchers investigated the Role of Cylicins in Spermiogenesis and Male Fertility in Mice and Humans through Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/ CRISPR-associated protein 9 (Cas9) Gene Editing.

30 Nov 2023

The effects of vitamin K on bone health

Existing scientific data on the effects of vitamin K (VK) on bone health and elucidated the underlying mechanisms.

30 Nov 2023

UTA biology student wins award for research on antimicrobial drug resistance

A senior biology student at The University of Texas at Arlington recently earned an award for her research about antimicrobial drug resistance.

29 Nov 2023

Genetic study sheds new light on the intricate link between sleep problems and psychiatric conditions

A massive genetic study involving almost 800,000 participants has uncovered genetic factors that contribute to the use of sleep medications, shedding new light on the intricate relationship between sleep problems and psychiatric conditions.

29 Nov 2023

UK Biobank data opens door to new era of precision medicine

In a momentous landmark for medical research, UK Biobank has today [Thursday 30 November] unveiled incredible new data from whole genome sequencing of its half a million participants.

29 Nov 2023

Research paves way for clinical trials of existing drugs for brain metastasis

The largest review of papers for brain cancer that has spread from the lungs has found abnormalities in the brain cancer and for which licensed drugs could be clinically trialled to find out if they could treat the disease.

29 Nov 2023

New insights into evolution of the “little brain”

The evolution of higher cognitive functions in human beings has so far mostly been linked to the expansion of the neocortex – a region of the brain that is responsible, inter alia, for conscious thought, movement and sensory perception.

29 Nov 2023

Mechanically reprogrammed connective tissue cells can promote wound healing

Researchers at PSI and ETH Zurich have taken connective tissue cells that have been mechanically reprogrammed to resemble stem cells and transplanted them into damaged skin.

29 Nov 2023