B Cell News and Research

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Researchers resolve long-standing mystery of enzyme's role in cell survival

St. Jude Children's Research Hospital solves mystery of enzyme's role in cell survival, offering clues of how immune system fights infection and possible strategies to treat problems ranging from heart attack to cancer.

23 May 2014

New discovery cracks code of metabolic pathway that allows certain cancerous tumors to thrive

In a breakthrough discovery at the Children's Medical Center Research Institute at UT Southwestern (CRI), a research team led by Ralph DeBerardinis, M.D., Ph.D., has taken a significant step in cracking the code of an atypical metabolic pathway that allows certain cancerous tumors to thrive, providing a possible roadmap for defeating such cancers.

23 May 2014

UCSB study shows that key protein in epithelial cells plays important roles in how cells sense direction

What do sled dogs and cell clusters have in common? According to research by UC Santa Barbara's Denise Montell, they both travel in groups and need a leader to make sure they all follow in the same direction.

23 May 2014

Researchers uncover potential vaccine that can stop malaria parasites from multiplying

Researchers have identified a substance, or antigen, that generates antibodies that can hinder the ability of malaria parasites to multiply, which may protect against severe malaria infection.

23 May 2014

New database allows researchers to match old drugs for new diseases

There are thousands of drugs that silence many thousands of cancer-causing genetic abnormalities. Some of these drugs are in use now, but many of these drugs are sitting on shelves or could be used beyond the disease for which they were originally approved.

23 May 2014

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Blocking a pain receptor in mice not only extends their lifespan, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood sugar.

23 May 2014

Researchers identify small molecule that prevents bacteria from forming into infectious biofilms

Researchers at the University of British Columbia have identified a small molecule that prevents bacteria from forming into biofilms, a frequent cause of infections.

23 May 2014

New antibody appears to block sensations of pain, itching in mouse model

Duke University researchers have found an antibody that simultaneously blocks the sensations of pain and itching in studies with mice.

23 May 2014

Danish researchers provide valuable insight into basic mechanisms of stem cell differentiation

The world has great expectations that stem cell research one day will revolutionize medicine. But in order to exploit the potential of stem cells, we need to understand how their development is regulated.

23 May 2014

NCCN receives $2M grant to evaluate effectiveness of volasertib in treatment of hematologic malignancies

The National Comprehensive Cancer Network® (NCCN®) Oncology Research Program (ORP) has been awarded a $2-million grant from Boehringer Ingelheim Pharmaceuticals, Inc.

23 May 2014

TUSM scientists receive $11.5M grant to develop innovative treatments for heart failure

Innovative treatments for heart failure are lacking, leaving the nearly six million Americans who suffer from the condition with little hope for a cure.

23 May 2014

Sex cell determination requires maintenance throughout life

The way in which the sex of an organism is determined may require lifelong maintenance, finds new research from the University of Minnesota.

23 May 2014

Separating sperm and eggs from somatic cells preserves genetic building blocks

We have hundreds of types of cells in our bodies - everything from red blood cells to hair follicles to neurons. But why can't most of them create offspring for us?

23 May 2014

EMA grants Advanced Therapy Medicinal Product classification for TxCell's Col-Treg

TxCell SA, a biotechnology company developing innovative, personalized cell-based immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that Col-Treg, its second therapeutic candidate from its ASTrIA platform, has been granted Advanced Therapy Medicinal Product (ATMP) classification by the Committee for Advanced Therapies (CAT) of the European Medicines Agency.

22 May 2014

Research findings could lead to new approach to Alzheimer’s prevention

In surprise findings, scientists at The Scripps Research Institute have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer’s disease aggregates when it is produced in the brain. The results suggest that drugs that can boost the protein’s production specifically in neurons could one day help ward off Alzheimer’s disease.

22 May 2014

Benefits of using VACUSAFE Laboratory Aspiration System for cell culture applications

INTEGRA has published a new video testimonial in which researchers at the Institute for Clinical Chemistry at the Technical University of Munich describe the benefits of using the VACUSAFE Laboratory Aspiration System to provide simple, reliable and safe aspiration of cell culture supernatents.

From INTEGRA Biosciences 22 May 2014

Acceleron, Celgene to give oral presentations on beta-thalassemia, myelodysplastic syndromes at EHA meeting

Acceleron Pharma Inc., a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of novel protein therapeutics for cancer and rare diseases, today reported that Acceleron, Celgene and investigators in the sotatercept and ACE-536 phase 2 clinical trials will give three oral presentations of interim data from ongoing studies in beta-thalassemia and myelodysplastic syndromes as well as a poster presentation of nonclinical data in sickle cell disease at the 19th Annual Congress of the European Hematology Association (EHA) in Milan, Italy from June 12-15, 2014.

22 May 2014

New 5-layer flask enhances cell culture production

Porvair Sciences has announced a new 5-layer cell culture flask developed to fulfil the need of the growing number of applications that require large numbers of cells.

From Chromatrap® - Porvair Sciences Ltd 22 May 2014

Researchers discover atypical type of retina cell that plays more critical role in vision

A type of retina cell plays a more critical role in vision than previously known, a team led by Johns Hopkins University researchers has discovered.

22 May 2014

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

In surprise findings, scientists at The Scripps Research Institute (TSRI) have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer's disease aggregates when it is produced in the brain.

22 May 2014

B Cell News and Research

Researchers resolve long-standing mystery of enzyme's role in cell survival

New discovery cracks code of metabolic pathway that allows certain cancerous tumors to thrive

UCSB study shows that key protein in epithelial cells plays important roles in how cells sense direction

Researchers uncover potential vaccine that can stop malaria parasites from multiplying

New database allows researchers to match old drugs for new diseases

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Researchers identify small molecule that prevents bacteria from forming into infectious biofilms

New antibody appears to block sensations of pain, itching in mouse model

Danish researchers provide valuable insight into basic mechanisms of stem cell differentiation

NCCN receives $2M grant to evaluate effectiveness of volasertib in treatment of hematologic malignancies

TUSM scientists receive $11.5M grant to develop innovative treatments for heart failure

Sex cell determination requires maintenance throughout life

Separating sperm and eggs from somatic cells preserves genetic building blocks

EMA grants Advanced Therapy Medicinal Product classification for TxCell's Col-Treg

Research findings could lead to new approach to Alzheimer’s prevention

Benefits of using VACUSAFE Laboratory Aspiration System for cell culture applications

Acceleron, Celgene to give oral presentations on beta-thalassemia, myelodysplastic syndromes at EHA meeting

New 5-layer flask enhances cell culture production

Researchers discover atypical type of retina cell that plays more critical role in vision

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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