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Scientists discover how MRP-14 gene generates dangerous clots that could trigger heart attack

Right now, options are limited for preventing heart attacks. However, the day may come when treatments target the heart attack gene, myeloid related protein-14 (MRP-14, also known as S100A9) and defang its ability to produce heart attack-inducing blood clots, a process referred to as thrombosis.

2 Apr 2014

Researchers develop new screening tool to help diagnose obstructive sleep apnea in children

Clinical investigators at the Children's Hospital of Eastern Ontario (CHEO) have developed a new screening tool to help diagnose obstructive sleep apnea in children. Their findings are published in Pediatric Pulmonology.

2 Apr 2014

Study finds that baclofen drug has potential to prevent cocaine relapse

Relapse is the most painful and expensive feature of drug addiction-even after addicted individuals have been drug-free for months or years, the likelihood of sliding back into the habit remains high. The National Institute on Drug Abuse estimates that 40 to 60 percent of addicted individuals will relapse, and in some studies the rates are as high as 80 percent at six months after treatment.

2 Apr 2014

Northwestern University awarded NIH grant to conduct phase III Parkinson's neuroprotective study

Tanya Simuni, M.D., medical director of Northwestern University's Parkinson's Disease and Movement Disorders Center, was awarded a grant from the National Institutes of Health to conduct a $16 million phase III study of the safety and efficacy of the drug isradipine as a potential neuroprotective agent in Parkinson's disease.

2 Apr 2014

Study demonstrates efficacy, tolerability of vemurafenib in aggressive form of metastatic melanoma

The Lancet Oncology has published results from the largest ever trial of a single melanoma treatment. The open label safety study was conducted to assess the tolerability of Zelboraf (vemurafenib), and featured 3,222 patients from across 44 countries.1 246 of these patients were from the UK.

2 Apr 2014

Study examines complications in adult tonsillectomies and impact on health care expenditures

A study released today of 36,210 adult tonsillectomy patients finds that 20 percent will have a complication, offering valuable new insights to a decades long discussion. The study, featured in the April 2014 issue of Otolaryngology-Head and Neck Surgery, examines the prevalence of complications in adult tonsillectomies and the impact on health care expenditures.

2 Apr 2014

Study shows link between breast-feeding and risk of child developing obesity

Many studies have focused on the influence of breast-feeding on child health. From analysis of data from the ELANCE cohort, Marie Fran-oise Rolland-Cachera, former researcher at Inserm and her co-workers in the Nutritional Epidemiology Research Team (EREN) have shown that breast-feeding has a protective effect on the risk of obesity at 20 years of age.

2 Apr 2014

New study shows how hospital services around clock affects patient care

A major new study is to look at how providing more hospital services around the clock affects patient care - and how cost effective it is.

From The University of Manchester 2 Apr 2014

First Edition: April 1, 2014

Today's early morning highlights from the major news organizations, including an array of stories as the health law's enrollment period comes to a close

1 Apr 2014

Excessive occupancy levels in hospitals increases risk of mortality of critically ill patients

Once a hospital reaches a certain occupancy level, the quality of care it provides deteriorates, increasing the risk of mortality of critically ill patients. What is worrying is that this safety 'tipping point' is reached at occupancy levels that are below 100%.

1 Apr 2014

Study of non-surgically implanted replacement pulmonary valve shows strong results

The first post-FDA approval study of a non-surgically implanted replacement pulmonary valve showed strong short- and mid-term results for the device in patients with certain congenital heart defects, according to research presented by a U-M pediatric interventional cardiologist at the American College of Cardiology's 63rd Annual Scientific Session Sunday.

1 Apr 2014

EMD Serono collaborates with Pfizer and Broad Institute

EMD Serono, a subsidiary of Merck KGaA, Darmstadt, Germany, today announced they have signed a research agreement with Pfizer Inc. and the Broad Institute in Cambridge, Massachusetts, U.S. The collaboration is focused on the genomic profiling of Systemic Lupus Erythematosus (SLE) and Lupus Nephritis (LN) patients.

1 Apr 2014

NeuroSigma gets approval to market Monarch eTNS System in Australia

NeuroSigma, Inc., a California-based life-sciences company focused on commercialization of its non-invasive Monarch eTNS System for the treatment of neurological and neuropsychiatric disorders, today announced that it has received approval from the Therapeutic Goods Administration to market its Monarch eTNS System in Australia.

1 Apr 2014

DTI assessment indicates that mild hypothermia therapy may be beneficial for patients with diffuse axonal injury

Mild hypothermia has been shown to exert apparent neuroprotective effects in animal models of diffuse axonal injury. However, the clinical efficacy of mild hypothermia is controversial.

1 Apr 2014

Providing health insurance coverage to uninsured people does not result in reduced readmission rates

Boston-In a first of its kind retrospective study, Boston University School of Medicine (BUSM) researchers have found that providing health insurance coverage to previously uninsured people does not result in reducing 30-day readmission rates.

1 Apr 2014

Research shows that men living alone have reduced melanoma-specific survival

There are differences in prognosis in cutaneous malignant melanoma depending on cohabitation status and gender, according to a new study published in the scientific periodical Journal of Clinical Oncology. Single men of all ages are more likely to die of their disease.

1 Apr 2014

Safer sharps: an interview with Paul Lindsell, Managing Director, MindMetre

In 2010, the European Council described sharps injuries as one of the most serious health and safety threats in European workplaces as an estimated one million injuries were occurring each year.

1 Apr 2014

People with low and very high levels of transferrin saturation ratio are at increased risk of death

A new study led by researchers at the Graduate Entry Medical School, University of Limerick has found that people with low levels and very high levels of a commonly measured laboratory test, the “transferrin saturation ratio” are at an increased risk of death. The test is a measure of the amount of available iron in the bloodstream with low levels generally reflecting a state of iron deficiency and high levels suggesting a relative excess.

1 Apr 2014

Bayer’s Adempas now available in the UK to treat patients with CTEPH

Adempas (riociguat) is available in the UK today as the first drug treatment for CTEPH, to treat adult patients with WHO Functional Class (FC) II to III with inoperable or persistent disease to improve exercise capacity.

1 Apr 2014

Second Sight's Argus II Retinal Prosthesis System selected for Forfait Innovation reimbursement

Second Sight Medical Products Inc. announces today that the Argus II Retinal Prosthesis System, the world’s first approved device intended to restore some functional vision for people suffering from blindness due to outer retinal degenerations, has become the first recipient of the French Government national healthcare reimbursement program entitled ‘Forfait Innovation’.

1 Apr 2014

Hospital News and Research

Scientists discover how MRP-14 gene generates dangerous clots that could trigger heart attack

Researchers develop new screening tool to help diagnose obstructive sleep apnea in children

Study finds that baclofen drug has potential to prevent cocaine relapse

Northwestern University awarded NIH grant to conduct phase III Parkinson's neuroprotective study

Study demonstrates efficacy, tolerability of vemurafenib in aggressive form of metastatic melanoma

Study examines complications in adult tonsillectomies and impact on health care expenditures

Study shows link between breast-feeding and risk of child developing obesity

New study shows how hospital services around clock affects patient care

First Edition: April 1, 2014

Excessive occupancy levels in hospitals increases risk of mortality of critically ill patients

Study of non-surgically implanted replacement pulmonary valve shows strong results

EMD Serono collaborates with Pfizer and Broad Institute

NeuroSigma gets approval to market Monarch eTNS System in Australia

DTI assessment indicates that mild hypothermia therapy may be beneficial for patients with diffuse axonal injury

Providing health insurance coverage to uninsured people does not result in reduced readmission rates

Research shows that men living alone have reduced melanoma-specific survival

Safer sharps: an interview with Paul Lindsell, Managing Director, MindMetre

People with low and very high levels of transferrin saturation ratio are at increased risk of death

Bayer’s Adempas now available in the UK to treat patients with CTEPH

Second Sight's Argus II Retinal Prosthesis System selected for Forfait Innovation reimbursement

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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