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Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Psoriasis etiopathogenesis and treatment.

29 Nov 2023

Study uncovers mechanisms underlying microglia-driven neuroinflammation in Alzheimer's disease

A study by Brigham investigators revealed how genetic changes in certain types of brain cells may contribute to the inflammatory response seen in Alzheimer's disease.

28 Nov 2023

Missing protein triggers alternative immune attack on cancer cells

Researchers at the UCLA Jonsson Comprehensive Cancer Center have found certain immune cells can still fight cancer even when the cancer cells lack an important protein that the immune system relies on to help track down cancer cells.

28 Nov 2023

Researchers discover new gene targets for precision oncology in esophageal cancer

Researchers have identified a new way to screen genes that cause several different types of cancers to grow, identifying particularly promising targets for precision oncology in oral and esophageal squamous cancers.

28 Nov 2023

Study identifies how three novel genes cause neurodevelopmental disorders

An international study group led by researchers of Children's Hospital of Philadelphia (CHOP) have identified how three novel genes cause neurodevelopmental disorders.

28 Nov 2023

New heart organoid model could revolutionize drug development and toxicology studies

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists – so far.

28 Nov 2023

Scientists uncover new therapeutic targets for high-risk pediatric leukemia

Scientists at St. Jude Children's Research Hospital comprehensively identified genes directly regulated by a protein associated with high-risk pediatric leukemias.

28 Nov 2023

Potential breakthrough in breast cancer: Five proteins identified as risk markers

Researchers used a Mendelian randomization approach to conduct a genetic association analysis of the levels of over 3,000 proteins to identify biomarkers for early breast cancer detection.

28 Nov 2023

Researchers develop $1 cancer treatment using engineered bacteria

What if a single one-dollar dose could cure cancer?

27 Nov 2023

Machine learning unlocks secrets of antimicrobial resistance, identifying over 900 key genes

Researchers employed advanced techniques like gene annotation, pangenomics, and machine learning to identify over 900 genes responsible for antimicrobial resistance in 12 bacterial species, outperforming traditional identification methods. This breakthrough approach offers new insights into the genetic basis of resistance, potentially guiding the development of more effective antibiotics

27 Nov 2023

DNA methylation: A key player in gene expression variation and disease manifestation

Professor Asaf Hellman and his research team at the Hebrew University-Hadassah Medical School have unveiled new findings in the realm of methylation-directed regulatory networks.

27 Nov 2023

RNA-based therapy shows promise for treating leukemia in animal models

Each year, about 13,000 people in Deutschland are diagnosed with leukemia, an umbrella term that encompasses various forms of blood cancer.

27 Nov 2023

Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

Synthetic biologists develop versatile platform for targeted drug delivery

In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases.

27 Nov 2023

Infant face preference linked to genetics

Whether infants at five months of age look mostly at faces or non-social objects such as cars or mobile phones is largely determined by genes.

27 Nov 2023

Fermented foods may have fueled human brain growth, new evolutionary theory proposes

Review in Communications Biology suggests that the external fermentation of foods may have played a key role in the expansion of the hominid brain. The "external fermentation hypothesis" posits that early hominins' practice of fermenting foods externally contributed to brain growth and gut reduction, offering a novel perspective on human evolution and dietary practices.

26 Nov 2023

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Research reveals how a fiber-free diet in Exclusive Enteral Nutrition (EEN) helps treat Crohn's disease in children by affecting the intestinal pathobiont Mucispirillum schaedleri. It shows that this diet alters gut microbiota, reducing Mucispirillum's pathogenicity and aiding in managing colitis.

26 Nov 2023

The potential of polyunsaturated fatty acids in alleviating depression and reducing suicide risk

Research in 'Molecular Psychiatry' explores the role of long-chain polyunsaturated fatty acids (LC-PUFAs) in major depressive disorder (MDD) and suicide risk, showing mixed results in clinical trials for depression treatment. The study underscores the need for further investigation into LC-PUFAs' neurobiology to advance personalized medicine for mood disorders and suicide prevention.

26 Nov 2023

Scientists succeed in mapping a central part of the immune system

A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system - the HLA class II molecules - while accurately predicting how they display fragments of pathogens on the surface of cells.

24 Nov 2023

New insights into how SARS-CoV-2 evades our immune system

This review in Cellular and Molecular Immunology delves into the innate immune response to SARS-CoV-2, exploring how the virus evades immunity and the potential role of innate immunity in long-COVID and vaccine responses, shedding light on future therapeutic strategies.

23 Nov 2023

Genes News and Research

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Study uncovers mechanisms underlying microglia-driven neuroinflammation in Alzheimer's disease

Missing protein triggers alternative immune attack on cancer cells

Researchers discover new gene targets for precision oncology in esophageal cancer

Study identifies how three novel genes cause neurodevelopmental disorders

New heart organoid model could revolutionize drug development and toxicology studies

Scientists uncover new therapeutic targets for high-risk pediatric leukemia

Potential breakthrough in breast cancer: Five proteins identified as risk markers

Researchers develop $1 cancer treatment using engineered bacteria

Machine learning unlocks secrets of antimicrobial resistance, identifying over 900 key genes

DNA methylation: A key player in gene expression variation and disease manifestation

RNA-based therapy shows promise for treating leukemia in animal models

Genetic mutation in OXR1 gene linked to brain development issues

Synthetic biologists develop versatile platform for targeted drug delivery

Infant face preference linked to genetics

Fermented foods may have fueled human brain growth, new evolutionary theory proposes

Fiber-free diet key to treating childhood Crohn's disease, new study finds

The potential of polyunsaturated fatty acids in alleviating depression and reducing suicide risk

Scientists succeed in mapping a central part of the immune system

New insights into how SARS-CoV-2 evades our immune system

eBook: Using iPSCs models for human disease research and drug discovery eBook

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