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Metadherin gene linked to metastasis of breast cancer

A team of researchers at Princeton University and The Cancer Institute of New Jersey has identified a long-sought gene that is fatefully switched on in 30 to 40 percent of all breast cancer patients, spreading the disease, resisting traditional chemotherapies and eventually leading to death.

5 Jan 2009

Few DNA repair gene variants associated with increased cancer risk

Variants of numerous DNA repair genes initially appeared to be statistically significantly associated with cancer risk in epidemiological studies.

1 Jan 2009

What are protective effects of anti-ricin A-chain aptamer?

Ricin, a lectin from the castor bean plant Ricinus communis is considered one of the most potent plant toxins.

30 Dec 2008

Protein FKBP12 provides new insights into understanding autism

Researchers at New York University's Center for Neural Science and the Baylor College of Medicine have identified a protein that when removed from mice results in behaviors that are akin to those with autism and obsessive-compulsive disorders.

10 Dec 2008

Protein-misfolding accelerates yeast evolution

Under stress, yeast cells can unleash a remarkable mechanism based on protein-misfolding that gives them new characteristics without requiring genetic mutations.

28 Nov 2008

New report shows the financial and social value of investing in medical research

A study commissioned by three leading scientific institutions has demonstrated substantial financial and social benefits from investment in medical research.

21 Nov 2008

Santaris Pharma releases positive data on LNA-based survivin inhibitor

Santaris Pharma announced today that SPC3042, a RNA-based antisense oligonucleotide developed using the company's proprietary Locked Nucleic Acid (LNA) technology, potently blocks survivin, a key survival protein in cancer cells, in both in vitro and in vivo models of prostate cancer. Importantly, SPC3042 works synergistically with the anticancer drug paclitaxel (Taxol) in both model systems.

10 Nov 2008

Canadian study to look at exercise and physical activity

We all know physical activity is good for you. But why exactly is it good for you? What effect does exercise have on the cells and tissues of the body?

5 Nov 2008

New cases of diagnosed diabetes rises 90% in last 10 years

The rate of new cases of diagnosed diabetes rose by more than 90 percent among adults over the last 10 years, according to a study by the Centers for Disease Control and Prevention (CDC).

31 Oct 2008

Webcam technology helps Arizona hospitals better communicate with non-English-speaking patients

A webcam language interpretation service is helping three Arizona hospitals better serve Spanish-speaking patients in their emergency departments, the East Valley & Scottsdale Tribune reports. The Iasis Healthcare hospitals had relied on telephone interpretation services before implementing the new webcam system.

16 Sep 2008

Neuroscientists discover a critical early step of memory formation

Researchers at the Johns Hopkins University School of Medicine report in the July issue of Neuron how nerve cells in the brain ensure that Arc, a protein critical for memory formation, is made instantly after nerve stimulation. Paradoxically, its manufacture involves two other proteins - including one linked to mental retardation - that typically prevent proteins from being made.

14 Sep 2008

Discovery of gene that could help develop HIV/AIDS vaccine

In an article published in the journal Science on Thursday, researchers announced that they have discovered a gene, called Apobec3, that might help in the development of an HIV/AIDS vaccine, Reuters Health reports.

9 Sep 2008

Novel imaging reagents and technology that non-invasively locates, quantifies specific cells in the body

Magnetic resonance imaging (MRI) isn't just for capturing detailed images of the body's anatomy. Thanks to novel imaging reagents and technology developed by Carnegie Mellon University scientist Eric Ahrens, MRI can be used to visualize - with "exquisite" specificity - cell populations of interest in the living body. The ability to non-invasively locate and track cells, such as immune cells, will greatly aid the study and treatment of cancer, inflammation, and autoimmune diseases, as well as provide a tool for advancing clinical translation of the emerging field of cellular regenerative medicine, by tracking stem cells for example.

21 Aug 2008

Clinical-scale generation of functional red blood cells from human embryonic stem cells

Advanced Cell Technology, Inc. reported that it is feasible to differentiate and mature human embryonic stem cells (hESCs) into functional oxygen-carrying red blood cells (RBCs) under conditions suitable for scale-up.

19 Aug 2008

Evolution in the ribosome

A new study of the ribosome, the cell's protein-building machinery, sheds light on the oldest branches of the evolutionary tree of life and suggests that differences in ribosomal structure between the three main branches of that tree are "molecular fossils" of the early evolution of protein synthesis.

18 Aug 2008

Massage speeds recovery after a sports injury

Researchers testing the long-held theory that therapeutic massage can speed recovery after a sports injury have found early scientific evidence of the healing effects of massage.

12 Aug 2008

How short RNAs influence many proteins

During the last decade, microRNAs have emerged somewhat surprisingly as key players in the way genes are regulated. These short snippets of RNA do their work by interacting with messenger RNAs, which act as blueprints for protein creation.

6 Aug 2008

Recovery from ante-partum bed rest - Case Western study

After weeks of bed rest during pregnancy, new mothers need to rebuild muscles and strengthen their stamina. Now a group of women will test new interventions in aiding that recovery during a pilot study at Case Western Reserve University's Frances Payne Bolton School of Nursing.

29 Jul 2008

Rochester launches first health survey of deaf population

This summer, researchers in the Rochester, N.Y., region are conducting the nation's first survey to measure the basic health status of deaf people and their knowledge of health issues.

29 Jul 2008

Culture differences in predicting variations in how people present symptoms of depression

The expectation that East-Asian people emphasize physical symptoms of depression (e.g. headaches, poor appetite or aches/pains in the body) is widely acknowledged, yet the few available empirical studies report mixed data on this issue.

15 Jul 2008