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PolyMedix receives FDA regulatory clearance for PMX-30063 IND application

PolyMedix, Inc. an emerging biotechnology company focused on developing new therapeutic drugs to treat infectious diseases and acute cardiovascular disorders, has received regulatory clearance from the United States Food and Drug Administration (FDA) for its Investigational New Drug (IND) application for PMX-30063, a synthetic defensin-mimetic antibiotic.

11 Nov 2010

Guardian examines former Pres. Bush's reflection on PEPFAR in new memoir

The Guardian examines the reflections of former President George W. Bush on the $15bn President's Emergency Plan for Aids Relief (PEPFAR) which distributed antiretroviral drugs to keep people with HIV alive, as the president describes in his recently released memoir, Decision Points.

11 Nov 2010

Infant foods must be protected against fumonisin toxin

An international team of scientists calls for protecting complementary food for infants in developing countries - especially those where corn is a staple food - against fumonisin, a toxin produced by fungi. Until now, physicians thought the growth retardation of children in those regions was to be blamed on the poor nutritional value of the complementary maize porridge they receive when breast milk is no longer sufficient. But toxins indeed are involved, the scientists report in the journal Molecular Nutrition and Food Research.

10 Nov 2010

Chocolates inhibit enzyme known to raise blood pressure

Numerous studies have shown that cocoa has a protective effect against cardiovascular diseases. The reason for this has now been uncovered by researchers at Linköping University in Sweden. When a group of volunteers devoured a good-sized piece of dark chocolate, it inhibited an enzyme in their bodies that is known to raise blood pressure.

10 Nov 2010

PolyMedix announces publication of defensin-mimetic compounds in Molecular Oral Microbiology

PolyMedix, Inc. an emerging biotechnology company focused on developing new therapeutic drugs to treat infectious diseases and acute cardiovascular disorders, announced that data from two separate pre-clinical research studies were published in the December issue of Molecular Oral Microbiology.

10 Nov 2010

Egrifta receives FDA approval for treatment of HIV-lipodystrophy

The U.S. Food and Drug Administration today approved Egrifta (tesamorelin) to treat HIV patients with lipodystrophy, a condition in which excess fat develops in different areas of the body, most notably around the liver, stomach, and other abdominal organs. The condition is associated with many antiretroviral drugs used to treat HIV.

10 Nov 2010

Obese teens become obese adults

A new report shows that obese adolescent Americans tend to carry their extra weight into adulthood. The nationally representative study of American youth showed that one in 12 teenagers became severely obese as they entered adulthood with some 100 pounds above their ideal weight. And nearly half the girls and more than a third of the boys who are obese as teenagers grew up to be obese adults with a high risk of developing heart disease, diabetes and certain types of cancers.

10 Nov 2010

China Medical Technologies' EGFR PCR Assay for lung cancer targeted drugs receives Chinese SFDA approval

China Medical Technologies, Inc., a leading China-based advanced in-vitro diagnostic ("IVD") company, today announced that it has received approval for its real-time PCR-based Epidermal Growth Factor Receptor Assay (the "EGFR PCR Assay") for the use of lung cancer targeted drugs from the State Food and Drug Administration of China (the "SFDA").

10 Nov 2010

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Using proton pump inhibitors and antiplatelet drugs (thienopyridines) together is an appropriate way of treating patients with cardiovascular disease who are at high risk of upper gastrointestinal bleeds, despite recent concerns about an adverse interaction between these two types of drugs, according to an Expert Consensus Document released jointly today by the American College of Cardiology Foundation, the American College of Gastroenterology, and the American Heart Association.

10 Nov 2010

Researchers identify molecular cascade that drives process of reconnection in adult brain after stroke

A stroke wreaks havoc in the brain, destroying its cells and the connections between them. Depending on its severity and location, a stroke can impact someone's life forever, affecting motor activity, speech, memories, and more.

10 Nov 2010

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

Researchers have further established that long-term use of statins is unlikely to substantially increase or decrease overall cancer risk, according to study results presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010, in Philadelphia.

10 Nov 2010

Breast cancer patients more likely to have joint pain from taking AIs: Study

Breast cancer patients are more likely to have joint pain from taking aromatase inhibitors if they have advanced stage cancer, according to a study presented at the American College of Rheumatology's annual meeting, held Nov. 7-11, in Atlanta. The study is one of the first to identify factors that increase the likelihood that a patient will suffer joint pain from AI therapy.

10 Nov 2010

NEWMEDS launches largest database to advance drug development for depressio, schizophrenia

In a remarkable and unprecedented collaboration NEWMEDS (Novel Methods leading to NeW MEdications in Depression and Schizophrenia) have pooled resources to bring together data of 23,401 anonymized patients from 67 trials on 11 compounds in over 25 countries to form the single largest database of clinical trial data ever amassed in psychiatric research.

10 Nov 2010

Contraceptive, antiviral gel using bee venom wins 2010 Gates Foundation grant

A vaginal gel that affords both contraception and HIV protection using nanoparticles that carry bee venom is one of the bold, unconventional ideas that won a 2010 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation.

10 Nov 2010

NCI awards $4 million for UNM's cancer nanotechnology partnership with Sandia Labs

The National Cancer Institute recently announced two five-year awards totaling nearly $4 million for a partnership between the University of New Mexico Cancer Center and Sandia National Laboratories. One $1.95 million grant will fund the creation of a joint Cancer Nanotechnology Platform Partnership, and another $1.8 million grant will pay for a new Cancer Nanotechnology Training Center to train a new generation of multidisciplinary scientists.

10 Nov 2010

Special Surgery investigators to present future of clinical care at ACR annual meeting

Hospital for Special Surgery physicians who focus on lupus, scleroderma and related conditions are traveling from New York City to Atlanta this week to share their recent findings at the 74th Annual Scientific Meeting of the American College of Rheumatology (ACR).

10 Nov 2010

Adolescent obesity associated with risk of severe obesity in adulthood

Obese adolescents are 16 times more likely to become severely obese by age 30 than their healthy weight or even overweight peers, according to a new study from the University of North Carolina at Chapel Hill.

10 Nov 2010

Aromatase inhibitors increase side effects in women undergoing breast cancer therapy

Women being treated for breast cancer with aromatase inhibitors may experience extremely low estrogen levels resulting in a wide variety of side effects that a typical postmenopausal woman without cancer may not experience.

10 Nov 2010

New York Times examines HIV prevention products undergoing clinical trials

The New York Times examines several products being studied in clinical trials that researchers hope will one day prevent sexual transmission of HIV. The newspaper describes the ongoing trials of a vaginal microbicide gel containing the antiretroviral tenofovir which was found to reduce the risk of HIV infection in women by 39 percent, writing, "[o]ther clinical trials will report their results in 2011 and 2012 and, if all goes well, researchers hope to have a product or two ready to enter the market by 2013."

10 Nov 2010

Albert Einstein researcher receives Medal of Honor from American Cancer Society

Albert Einstein College of Medicine of Yeshiva University researcher Jeffrey Pollard, Ph.D., has received the prestigious Medal of Honor in Basic Science from the American Cancer Society (ACS) in recognition of his research into the critical role the tumor microenvironment plays in modulating cancer behavior, specifically the role that members of the innate immune cells called macrophages play both in normal development and in promoting tumor progression. These macrophages could hold the key to more targeted cancer treatments.

10 Nov 2010

Drugs News and Research

PolyMedix receives FDA regulatory clearance for PMX-30063 IND application

Guardian examines former Pres. Bush's reflection on PEPFAR in new memoir

Infant foods must be protected against fumonisin toxin

Chocolates inhibit enzyme known to raise blood pressure

PolyMedix announces publication of defensin-mimetic compounds in Molecular Oral Microbiology

Egrifta receives FDA approval for treatment of HIV-lipodystrophy

Obese teens become obese adults

China Medical Technologies' EGFR PCR Assay for lung cancer targeted drugs receives Chinese SFDA approval

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Researchers identify molecular cascade that drives process of reconnection in adult brain after stroke

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

Breast cancer patients more likely to have joint pain from taking AIs: Study

NEWMEDS launches largest database to advance drug development for depressio, schizophrenia

Contraceptive, antiviral gel using bee venom wins 2010 Gates Foundation grant

NCI awards $4 million for UNM's cancer nanotechnology partnership with Sandia Labs

Special Surgery investigators to present future of clinical care at ACR annual meeting

Adolescent obesity associated with risk of severe obesity in adulthood

Aromatase inhibitors increase side effects in women undergoing breast cancer therapy

New York Times examines HIV prevention products undergoing clinical trials

Albert Einstein researcher receives Medal of Honor from American Cancer Society

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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