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Study shows how ketamine administration starkly changes neuronal activity patterns in the brain

Ketamine, an established anesthetic and increasingly popular antidepressant, dramatically reorganizes activity in the brain, as if a switch had been flipped on its active circuits, according to a new study by Penn Medicine researchers.

1 Dec 2022

Human T cell immunity is coping with mutations in SARS-CoV-2 variants of concern

Immune T cells are continuing to target the spike protein of SARS-CoV-2 variants of concern, although mutations are making some T cells less effective, according to new research.

1 Dec 2022

Research shows biological sex as a crucial factor in the effectiveness of anti-aging drugs

The effect of medicines on women and men can differ significantly. This also applies to the currently most promising anti-aging drug rapamycin, as researchers from the Max Planck Institute for Biology of Ageing in Cologne and University College London have now shown.

1 Dec 2022

Using DECT-derived metrics to definitively diagnose incidental adrenal adenomas

According to an open-access Editor's Choice accepted manuscript published in ARRS' American Journal of Roentgenology, for adrenal lesions evaluated by single-phase dual-energy CT (DECT), fat fraction had higher sensitivity than virtual non-contrast attenuation at both the clinically optimal threshold and at the traditional ≤10 HU threshold.

1 Dec 2022

New metagenomic study reveals global landscape of antimicrobial resistance

There are large geographical differences in both how frequently resistant genes occur and in which types of bacteria the genes are found.

1 Dec 2022

COVID-19 infection may lead to long-term liver injury

COVID-19 infection is associated with increased liver stiffness, a sign of possible long-term liver injury, according to the results of a new study being presented today at the annual meeting of the Radiological Society of North America.

1 Dec 2022

Two experimental mRNA vaccines highly effective in reducing malaria infection and transmission

Malaria is found in more than 90 countries around the world, causing 241 million cases and an estimated 627,000 deaths every year.

1 Dec 2022

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Dec 2022

Study identifies optimal blood tests for Alzheimer's detection and disease monitoring

A new study have identified which blood tests are best at detecting Alzheimer's disease during the earliest stages, and another blood test that is optimal for detecting relevant treatment effects.

1 Dec 2022

Research shows promising results using neurotechnological approaches to treat youth depression

New research shows promising results using neurotechnological approaches to treat depression in youth. The research, led by Simon Fraser University (SFU) professor Faranak Farzan, is published in the Journal of Affective Disorders Reports.

1 Dec 2022

Discontinuation of opioid therapy for pain may increase overdose risk

Opioid-related overdose is now a leading cause of accidental death in the United States and Canada. A study published December 1st in the open access journal PLOS Medicine by Mary Clare Kennedy at University of British Columbia, Kelowna, Canada, and colleagues suggests discontinuing prescribed opioids was associated with increased overdose risk.

1 Dec 2022

New evidence on the links between immune activation and neuroinflammation and Parkinson's disease

In this special supplement to the Journal of Parkinson's Disease, "The Immune System in Parkinson's Disease," experts highlight the latest research breakthroughs on the links between immune activation and neuroinflammation and Parkinson's disease (PD) and discuss the challenges and novel therapeutic strategies targeting the immune system with the hope of reducing or reversing neurodegeneration.

1 Dec 2022

Study implicates a specific type of brain cell as key player underlying the impact of stressors

More than 70% of adults will experience at least one traumatic experience, such as a life-threatening illness or accident, violent assault or natural disaster, in their lifetimes and nearly a third will experience four or more, according to global data.

1 Dec 2022

New, nanotech-based strategy could enable safe, long-term treatment for autoimmune diseases

Scientists at Scripps Research have reported success in initial tests of a new, nanotech-based strategy against autoimmune diseases.

1 Dec 2022

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

1 Dec 2022

Firearm-injured kids have a high rate of developing new mental health diagnoses

Children and teens who survive a firearm injury have a high rate of developing new mental health diagnoses in the year afterward, even compared with kids who suffered injuries in a motor vehicle crash, a new study shows.

1 Dec 2022

Fibromuscular dysplasia and abdominal aortic aneurysm have a “shared complex genetic architecture”

One disease is more common in people assigned female at birth, while the other is more common in people assigned male at birth.

1 Dec 2022

Study shows only 75.8% of children under 15 have antibodies against measles

A study conducted in Brazil and reported in an article in Vaccines shows that in the São José do Rio Preto region in the northwest of São Paulo state, only 75.8% of children aged 0-15 have antibodies against measles.

1 Dec 2022

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

1 Dec 2022

UTHealth Houston professor wins $3.5 million to study the mechanisms of brain receptors involved in neurological disorders

A five-year, nearly $3.5 million grant to study the mechanisms of brain receptors involved in neurological disorders such as learning disabilities has been awarded to Vasanthi Jayaraman, PhD, of UTHealth Houston by the National Institutes of Health.

1 Dec 2022

Research News and Research

Study shows how ketamine administration starkly changes neuronal activity patterns in the brain

Human T cell immunity is coping with mutations in SARS-CoV-2 variants of concern

Research shows biological sex as a crucial factor in the effectiveness of anti-aging drugs

Using DECT-derived metrics to definitively diagnose incidental adrenal adenomas

New metagenomic study reveals global landscape of antimicrobial resistance

COVID-19 infection may lead to long-term liver injury

Two experimental mRNA vaccines highly effective in reducing malaria infection and transmission

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Study identifies optimal blood tests for Alzheimer's detection and disease monitoring

Research shows promising results using neurotechnological approaches to treat youth depression

Discontinuation of opioid therapy for pain may increase overdose risk

New evidence on the links between immune activation and neuroinflammation and Parkinson's disease

Study implicates a specific type of brain cell as key player underlying the impact of stressors

New, nanotech-based strategy could enable safe, long-term treatment for autoimmune diseases

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Firearm-injured kids have a high rate of developing new mental health diagnoses

Fibromuscular dysplasia and abdominal aortic aneurysm have a “shared complex genetic architecture”

Study shows only 75.8% of children under 15 have antibodies against measles

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

UTHealth Houston professor wins $3.5 million to study the mechanisms of brain receptors involved in neurological disorders

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