B Cell News and Research

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Study finds ovarian cancer cells are more aggressive on soft tissues due to mechanical properties of environment

When ovarian cancer spreads from the ovaries it almost always does so to a layer of fatty tissue that lines the gut.

9 May 2014

Cellectricon, Neusentis to host webinar on phenotypic screening approaches in pain research

Cellectricon, a leading provider of advanced cell-based screening technologies and services, will co-host a webinar with Neusentis, describing the use of native cells to develop an assay with improved physiological relevance over traditional approaches in pain drug discovery research.

From Cellectricon 8 May 2014

TSRI scientists create bacteria with expanded DNA code

Scientists at The Scripps Research Institute have engineered a bacterium whose genetic material includes an added pair of DNA “letters,” or bases, not found in nature. The cells of this unique bacterium can replicate the unnatural DNA bases more or less normally, for as long as the molecular building blocks are supplied.

8 May 2014

Finding has implications for understanding cognitive decline in degenerative diseases

New research suggests that certain types of brain cells may be "picky eaters," seeming to prefer one specific energy source over others. The finding has implications for understanding the cognitive decline seen in aging and degenerative diseases such as Alzheimer's and multiple sclerosis.

8 May 2014

New technique expands number of functional cord blood stem cells for transplantation

Adults suffering from diseases such as leukemia, lymphoma, and other blood-related disorders may benefit from life-saving treatment commonly used in pediatric patients. Researchers at the Icahn School of Medicine at Mount Sinai have identified a new technique that causes cord blood (CB) stems cells to generate in greater numbers making them more useful in adult transplantation.

8 May 2014

TAG-1 induces apoptosis-related gene expression without triggering apoptosis in glioma cells

A recent study reported by Haigang Chang and co-workers from the First Affiliated Hospital of Xinxiang Medical University in China verified the effects of transient axonal glycoprotein-1 (TAG-1) on cell viability and p53, epidermal growth factor receptor (EGFR), and amyloid precursor protein (APP) intracellular C-terminal domain (AICD) expression in U251 glioma cells.

8 May 2014

Leica and Affymetrix launch fully automated RNA in situ hybridization assays

Affymetrix, Inc. (NASDAQ:AFFX) and Leica Biosystems announce the launch of Affymetrix' fully automated RNA in situ hybridization assays ViewRNATM eZ Assays on the Leica BOND RX staining platform.

8 May 2014

3 pioneering cell biologists win 2014 E.B. Wilson Medal from American Society for Cell Biology

If cells were cars, then the three pioneering cell biologists just named winners of the 2014 E.B. Wilson Medal, the highest scientific honor of the American Society for Cell Biology, helped write the essential parts list.

8 May 2014

Study: Elevated levels of atmospheric CO2 threaten human nutrition

At the elevated levels of atmospheric CO2 anticipated by around 2050, crops that provide a large share of the global population with most of their dietary zinc and iron will have significantly reduced concentrations of those nutrients, according to a new study led by Harvard School of Public Health (HSPH).

8 May 2014

New hydrogel instantly turns from liquid to semisolid at close to body temperature

Rice University bioengineers have created a hydrogel that instantly turns from liquid to semisolid at close to body temperature - and then degrades at precisely the right pace.

8 May 2014

Scientists find 2 key proteins that regulate growth of mammary stem cells and contribute to breast cancer

By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary stem cells-those that can form breast tissue-alive and functioning in the lab. The new ability to propagate mammary stem cells is allowing them to study both breast development and the formation of breast cancers.

8 May 2014

Neuron-to-neuron communication plays essential role in development of synapses

A study has shown that a long-overlooked form of neuron-to-neuron communication called miniature neurotransmission plays an essential role in the development of synapses, the regions where nerve impulses are transmitted and received.

8 May 2014

Mouse mothers can protect pups from developing type 1 diabetes by eating gluten-free diet

New experiments on mice show, that mouse mothers can protect their pups from developing type 1 diabetes by eating a gluten-free diet. According to preliminary studies by reseachers at the University of Copenhagen, the findings may apply to humans.

8 May 2014

Bioengineers develop tool that reacts to chemical changes caused by cancer cells

Bioengineers at the University of Rome Tor Vergata and the University of Montreal have used DNA to develop a tool that detects and reacts to chemical changes caused by cancer cells and that may one day be used to deliver drugs to tumor cells.

8 May 2014

Ligand's total revenues increase 37% to $16.0 million in first quarter 2014

Ligand Pharmaceuticals Incorporated today reported financial results for the three months ended March 31, 2014, and provided an operating forecast and program updates.

7 May 2014

ARIAD provides update on corporate developments, reports Q1 2014 financial results

ARIAD Pharmaceuticals, Inc. today reported financial results for the first quarter of 2014, including revenue from sales of Iclusig® (ponatinib) and licensing agreements. The Company also provided an update on corporate developments.

7 May 2014

New approach to detect chromosomal abnormalities without harm to mother or fetus

Chromosomal abnormalities that result in birth defects and genetic disorders like Down syndrome remain a significant health burden in the United States and throughout the world, with some current prenatal screening procedures invasive and a potential risk to mother and unborn child.

7 May 2014

RPCI research finds patients with metastatic kidney cancer benefit from HDIL-2 immunotherapy

A retrospective study published online ahead of print in the medical journal Urology by a physician team from Roswell Park Cancer Institute (RPCI) found that patients with metastatic kidney cancer — even those with chronic renal insufficiency — can tolerate and benefit from a treatment called high-dose interleukin-2 (HDIL-2) immunotherapy.

7 May 2014

New data presented at EADO on investigational MEK inhibitor in combination with BRAF inhibitor for metastatic melanoma

New data have been presented for the first time at the European Association of Dermato Oncology (EADO) Congress today on the investigational MEK inhibitor cobimetinib (GDC-0973) in combination with BRAFV600 inhibitor Zelboraf® (vemurafenib) for metastatic melanoma, the most aggressive form of skin cancer. The findings illustrate that cobimetinib and vemurafenib can be safely co-administered and that the combination shows promising anti-tumour activity, with a median progression-free survival (mPFS) of 13.7 months for BRAF inhibitor-naive patients.1

7 May 2014

New model mimics structure of cornea to enable transplant of healthy corneal stem cells

Scientists have developed a model that mimics the complex structure of the cornea to enable the transplant of healthy corneal stem cells.

7 May 2014

B Cell News and Research

Study finds ovarian cancer cells are more aggressive on soft tissues due to mechanical properties of environment

Cellectricon, Neusentis to host webinar on phenotypic screening approaches in pain research

TSRI scientists create bacteria with expanded DNA code

Finding has implications for understanding cognitive decline in degenerative diseases

New technique expands number of functional cord blood stem cells for transplantation

TAG-1 induces apoptosis-related gene expression without triggering apoptosis in glioma cells

Leica and Affymetrix launch fully automated RNA in situ hybridization assays

3 pioneering cell biologists win 2014 E.B. Wilson Medal from American Society for Cell Biology

Study: Elevated levels of atmospheric CO2 threaten human nutrition

New hydrogel instantly turns from liquid to semisolid at close to body temperature

Scientists find 2 key proteins that regulate growth of mammary stem cells and contribute to breast cancer

Neuron-to-neuron communication plays essential role in development of synapses

Mouse mothers can protect pups from developing type 1 diabetes by eating gluten-free diet

Bioengineers develop tool that reacts to chemical changes caused by cancer cells

Ligand's total revenues increase 37% to $16.0 million in first quarter 2014

ARIAD provides update on corporate developments, reports Q1 2014 financial results

New approach to detect chromosomal abnormalities without harm to mother or fetus

RPCI research finds patients with metastatic kidney cancer benefit from HDIL-2 immunotherapy

New data presented at EADO on investigational MEK inhibitor in combination with BRAF inhibitor for metastatic melanoma

New model mimics structure of cornea to enable transplant of healthy corneal stem cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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