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Glial cells promise as new target to modulate retinal synaptic plasticity after retinal injury

Different types of retinal damage could induce plastic changes of retinal synapses, which might precede the serious damage of neuron soma.

7 May 2014

Researchers discover genetic risk factor for premature birth

Researchers at the University of California, San Diego School of Medicine have discovered a genetic risk factor for premature birth.

7 May 2014

IKKβ links vascular inflammation to obesity and atherosclerosis development

A study in The Journal of Experimental Medicine shows that IκB kinase β (IKKβ) functions in smooth muscle cells to regulate vascular inflammatory responses and atherosclerosis development.

7 May 2014

Novel bioinformatics approach suggests antimicrobial drug may help in treating advanced kidney cancer

Developing and testing a new anti-cancer drug can cost billions of dollars and take many years of research.

6 May 2014

FDA accepts Merck's MK-3475 BLA for review

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for review the Biologics License Application (BLA) for MK-3475, Merck's investigational anti-PD-1 antibody, for the treatment of unresectable or metastatic melanoma in patients who have been previously treated with ipilimumab.

6 May 2014

Johns Hopkins researchers awarded NIH contract to launch new center to track influenza viruses

The National Institutes of Health has awarded a contract to researchers at The Johns Hopkins University to launch a new center devoted to developing innovative ways to identify and track influenza viruses worldwide.

6 May 2014

Nanoviricides develops new drug candidates against MERS infection

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6 May 2014

Phasefocus invited to present a two day workshop on label-free cell imaging at CATIM

Phase Focus Ltd (Phasefocus), the company that is revolutionising microscopy and imaging with the Phasefocus Virtual Lens®, has been invited to present a two day workshop on label-free cell imaging at CATIM – the Centre for Alternative Testing and In-vitro Monitoring on Tuesday 24th and Wednesday 25th June. The meeting will take place at the Frenchay Campus of the University of the West of England, Bristol.

From Phase Focus Limited 6 May 2014

New study explores how bacterial pathogen Yersinia tries to outsmart immune cell responses

A new study led by scientists at the University of Pennsylvania School of Veterinary Medicine has painted a clearer picture of the delicate arms race between the human immune system and a pathogen that seeks to infect and kill human cells.

6 May 2014

Bristol-Myers Squibb to present new immunotherapy study data at ASCO Annual Meeting

Bristol-Myers Squibb Company today announced that new data from studies investigating its immunotherapies in adjuvant and advanced melanoma, non-small cell lung cancer (NSCLC) and metastatic renal cell carcinoma (mRCC) will be presented at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago from May 30-June 3.

6 May 2014

Young blood can rejuvenate brains of old mice

Something - or some things - in the blood of young mice has the ability to restore mental capabilities in old mice, a new study by Stanford University School of Medicine investigators has found.

6 May 2014

NCCN publishes new patient resource for stage 0 breast cancer

The National Comprehensive Cancer Network (NCCN), with the support of the NCCN Foundation®, announces the availability of the NCCN Guidelines for Patients: Breast Cancer Stages 0 - IV—the latest addition to the library of NCCN Guidelines for Patients available online free-of-charge at NCCN.org/patients.

6 May 2014

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

Cajal-Retzius cells are reelin-secreting neurons in the marginal zone of the neocortex and hippocampus.

6 May 2014

Study reveals how ovarian cancer metabolism changes between early, late stages

A Rice University-led analysis of the metabolic profiles of hundreds of ovarian tumors has revealed a new test to determine whether ovarian cancer cells have the potential to metastasize, or spread to other parts of the body. The study also suggests how ovarian cancer treatments can be tailored based on the metabolic profile of a particular tumor.

6 May 2014

Scientists develop bone marrow-on-a-chip to test effects of new drugs, toxic agents on bone marrow

The latest organ-on-a-chip from Harvard's Wyss Institute for Biologically Inspired Engineering reproduces the structure, functions and cellular make-up of bone marrow, a complex tissue that until now could only be studied intact in living animals, Institute researchers report in the May 4, 2014, online issue of Nature Methods.

6 May 2014

MEI Pharma begins ME-344 Phase Ib clinical study in patients with solid tumors

MEI Pharma, Inc., an oncology company focused on the clinical development of novel therapies for cancer, announced today that the first patient has been dosed in a Phase Ib clinical study of its investigational mitochondrial inhibitor drug candidate ME-344 in combination with Hycamtin (topotecan) in patients with solid tumors, including small cell lung and ovarian cancers.

6 May 2014

Novogen partners with Genea Biocells to accelerate testing for neurodegenerative diseases

Novogen Limited, an oncology drug development company, today announced a collaboration with Australian company, Genea Biocells, to accelerate testing of their super-benzopyran (SBP) drugs for degenerative diseases of the nervous system and muscles.

5 May 2014

Alcohol consumption linked with increased risk of advanced liver fibrosis in HIV patients

Consumption of alcohol has long been associated with an increased risk of advanced liver fibrosis, but a new study published online in Clinical Infectious Diseases from researchers at Penn Medicine and other institutions shows that association is drastically heightened in people co-infected with both HIV and chronic hepatitis C virus (HCV) infection.

5 May 2014

FABP5 protein enhances cognitive function

Case Western Reserve researchers have discovered that a protein previously implicated in disease plays such a positive role in learning and memory that it may someday contribute to cures of cognitive impairments.

5 May 2014

Researchers analyze living cells quickly and accurately using Raman spectroscopy

In order to investigate inflammation, tumors or stem cells, medical practitioners analyze living cells. Non-invasive optical procedures such as Raman spectroscopy accelerate this procedure. Researchers have now developed it to industrial scale.

5 May 2014

B Cell News and Research

Glial cells promise as new target to modulate retinal synaptic plasticity after retinal injury

Researchers discover genetic risk factor for premature birth

IKKβ links vascular inflammation to obesity and atherosclerosis development

Novel bioinformatics approach suggests antimicrobial drug may help in treating advanced kidney cancer

FDA accepts Merck's MK-3475 BLA for review

Johns Hopkins researchers awarded NIH contract to launch new center to track influenza viruses

Nanoviricides develops new drug candidates against MERS infection

Phasefocus invited to present a two day workshop on label-free cell imaging at CATIM

New study explores how bacterial pathogen Yersinia tries to outsmart immune cell responses

Bristol-Myers Squibb to present new immunotherapy study data at ASCO Annual Meeting

Young blood can rejuvenate brains of old mice

NCCN publishes new patient resource for stage 0 breast cancer

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

Study reveals how ovarian cancer metabolism changes between early, late stages

Scientists develop bone marrow-on-a-chip to test effects of new drugs, toxic agents on bone marrow

MEI Pharma begins ME-344 Phase Ib clinical study in patients with solid tumors

Novogen partners with Genea Biocells to accelerate testing for neurodegenerative diseases

Alcohol consumption linked with increased risk of advanced liver fibrosis in HIV patients

FABP5 protein enhances cognitive function

Researchers analyze living cells quickly and accurately using Raman spectroscopy

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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