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New technique to examine how proteins interact at level of single HIV viral particle

An interdisciplinary team of scientists from KU Leuven in Belgium has developed a new technique to examine how proteins interact with each other at the level of a single HIV viral particle.

5 May 2014

Mixing stem cells with clay to regenerate human tissue

Gels made from clay could provide an environment that would stimulate stem cells to regenerate damaged tissues such as bone, skin, heart, spinal cord, liver, pancreas and cornea.

5 May 2014

Puzzle in breast cancer solved

In a new study published in Cell Reports, scientists at the Fred Hutchinson Cancer Research Center demonstrate that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed to cancer.

5 May 2014

Research: Novel therapeutic approach to overcome chemoresistance in ovarian cancer

Inhibiting enzymes that cause changes in gene expression could decrease chemotherapy resistance in ovarian cancer patients, researchers at Georgia State University and the University of Georgia say.

5 May 2014

Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

Johns Hopkins biochemists have figured out what is needed to activate and sustain the virus-fighting activity of an enzyme found in CD4+ T cells, the human immune cells infected by HIV. The discovery could launch a more effective strategy for preventing the spread of HIV in the body with drugs targeting this enzyme, they say.

2 May 2014

UCSD neurosurgeons study MRI-guided biopsy approach to diagnose patients with brain cancer

Neurosurgeons at UC San Diego Heath System have, for the first time, combined real-time magnetic resonance imaging (MRI) technology with novel non-invasive cellular mapping techniques to develop a new biopsy approach that increases the accuracy of diagnosis for patients with brain cancer.

2 May 2014

Study provides insight into effects of interleukin-27 in regulatory T-cell biology, physiological functions of IL-27

In a new report published in the Journal of Leukocyte Biology, scientists lay the groundwork for the development of novel tumor therapies that may help rid the body of cancer by inhibiting the recruitment of a specific suppressive immune cell type called "regulatory T-cells." The approach described in the report shows that an immune molecule, called interleukin-27, promotes the recruitment of regulatory T-cells.

2 May 2014

Newly discovered molecule provides drug target for controlling both asthma and cancerous tumor growth

A newly discovered molecule provides a new drug target for controlling both asthma-induced muscle thickening and cancerous tumor growth. This molecule, called "microRNA-10a," normally helps genes produce proteins or make copies of themselves, also play an important role in the growth or overgrowth of human airway smooth muscle cells and some forms of cancer.

2 May 2014

New findings show combination of statins and omega-3 fatty acid may potentially reduce cardiovascular risk

New findings from an in vitro study, led by researchers at Brigham and Women's Hospital (BWH), show that the combination of statins and eicosapentaenoic acid (EPA), an omega-3 fatty acid, may potentially reduce cardiovascular risk.

2 May 2014

Six-way jet-in-air sorter from Beckman Coulter Life Sciences delivers simultaneous high-speed cell sorting and sub-micron particle detection

MoFlo Astrios EQ, a six-way jet-in-air sorter from Beckman Coulter Life Sciences, delivers patent pending enhanced dual forward scatter (eFSC) technology for simultaneous sorting and detection of particles from 200 nm to 30 µm in diameter. The instrument sets a new standard for flow cytometry core facilities, delivering high-speed cell sorting and micro-particle detection in a single package. Featuring detailed and precise forward scatter resolution, beadless drop sample handling and increased biosafety, Astrios EQ meets a range of analysis needs.

2 May 2014

Scientists find key information that may lead to new therapeutic approaches to epilepsy

A team of researchers from Sanford-Burnham Medical Research Institute (Sanford-Burnham) and SUNY Downstate Medical Center (SUNY Downstate) has found that deficiencies in hyaluronan, also known as hyaluronic acid or HA, can lead to spontaneous epileptic seizures.

2 May 2014

New computational model rapidly assess therapy outcomes in prostate cancer patients with bone metastasis

A new computational model that simulates bone metastasis of prostate cancer has the potential to rapidly assess experimental therapy outcomes and help develop personalized medicine for patients with this disease, according to data published in Cancer Research, a journal of the American Association for Cancer Research.

2 May 2014

LUNGevity Foundation welcomes FDA approval of Zykadia drug for advanced stages of lung cancer

LUNGevity Foundation applauds the FDA approval of Zykadia™ for the subset of anaplastic lymphoma kinase-positive (ALK+) patients with advanced cases of non-small cell lung cancer who have progressed on or are intolerant to crizotinib.

2 May 2014

Virginia researchers develop new combination therapy that could potentially treat multiple myeloma

Each year, more than 25,000 Americans are diagnosed with multiple myeloma, a form of blood cancer that often develops resistance to therapies.

2 May 2014

$RTOG 9003: Hyperfractionated RT improves overall survival in patients with head and neck cancer$

RTOG 9003: Hyperfractionated RT improves overall survival in patients with head and neck cancer

Patients with locally advanced squamous cell carcinoma of the head and neck treated with hyperfractionated radiation therapy (HFX) experienced improved local-regional control and, with patients censored at five years, improved overall survival with no increase in late toxicity, according to a study published in the May 1, 2014 edition of the International Journal of Radiation Oncology ● Biology ● Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO).

2 May 2014

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Northwestern Medicine- scientists have newly identified a protein's key role in cell and physiological aging and have developed - in collaboration with Tohoku University in Japan -- an experimental drug that inhibits the protein's effect and prolonged the lifespan in a mouse model of accelerated aging.

2 May 2014

Biotech to the rescue

MIT professor Ram Sasisekharan's three biotech companies — Momenta Pharmaceuticals, Cerulean Pharma, and Visterra — share a similar goal.

1 May 2014

Human fat: A Trojan horse to fight brain cancer?

Johns Hopkins researchers say they have successfully used stem cells derived from human body fat to deliver biological treatments directly to the brains of mice with the most common and aggressive form of brain tumor, significantly extending their lives.

1 May 2014

Possible link between aggressive prostate cancer and vitamin D deficiency

Vitamin D deficiency was an indicator of aggressive prostate cancer and spread of the disease in European-American and African-American men who underwent their first prostate biopsy because of abnormal prostate-specific antigen (PSA) and/or digital rectal examination (DRE) test results, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

1 May 2014

Single treatment for AMD 'unlikely'

Age-related macular degeneration does not follow the same disease course from one patient to another, conclude researchers who suggest that phenotyping may be important before initiating a therapeutic trial.

1 May 2014

B Cell News and Research

New technique to examine how proteins interact at level of single HIV viral particle

Mixing stem cells with clay to regenerate human tissue

Puzzle in breast cancer solved

Research: Novel therapeutic approach to overcome chemoresistance in ovarian cancer

Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

UCSD neurosurgeons study MRI-guided biopsy approach to diagnose patients with brain cancer

Study provides insight into effects of interleukin-27 in regulatory T-cell biology, physiological functions of IL-27

Newly discovered molecule provides drug target for controlling both asthma and cancerous tumor growth

New findings show combination of statins and omega-3 fatty acid may potentially reduce cardiovascular risk

Six-way jet-in-air sorter from Beckman Coulter Life Sciences delivers simultaneous high-speed cell sorting and sub-micron particle detection

Scientists find key information that may lead to new therapeutic approaches to epilepsy

New computational model rapidly assess therapy outcomes in prostate cancer patients with bone metastasis

LUNGevity Foundation welcomes FDA approval of Zykadia drug for advanced stages of lung cancer

Virginia researchers develop new combination therapy that could potentially treat multiple myeloma

RTOG 9003: Hyperfractionated RT improves overall survival in patients with head and neck cancer

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Biotech to the rescue

Human fat: A Trojan horse to fight brain cancer?

Possible link between aggressive prostate cancer and vitamin D deficiency

Single treatment for AMD 'unlikely'

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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