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VUMC, UCSF investigators awarded $6 million NIH grant to develop implantable artificial kidney

The National Institutes of Health has awarded a four-year, $6 million grant to investigators at Vanderbilt University Medical Center and the University of California at San Francisco to develop an implantable artificial kidney.

3 Nov 2015

$Viking begins VK5211 Phase 2 trial in patients recovering from hip fracture$

Viking begins VK5211 Phase 2 trial in patients recovering from hip fracture

Viking Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on the development of novel, first-in-class or best-in-class therapies for metabolic and endocrine disorders, today announced the initiation of dosing in the company's Phase 2 clinical trial of VK5211 in patients who recently suffered a hip fracture.

3 Nov 2015

Winners of 'Scopus Awards Romania 2015' announced

Elsevier, a world-leading provider of scientific, technical and medical information products and services, has announced the winners of the "Scopus Awards Romania 2015" in two categories: Research Excellence and Journal Excellence. These awards were launched for the first time in Romania and aim to showcase good practice in research to inspire and further motivate the Romanian research community.

3 Nov 2015

Researchers develop biochemical trick that can extend lifespan of peptides

Researchers at University of the Pacific have developed a biochemical trick that can significantly extend the lifespan of peptides, smaller cousins of proteins. The finding opens up new possibilities for creating peptides to treat cancer, infertility and other conditions.

3 Nov 2015

Study identifies potential new approaches to curing parasitic diseases

A study in the Proceedings of the National Academy of Sciences shows that some forms of the single celled parasites, Trypanosoma brucei and Toxoplasma gondii behave like cancer cells.

3 Nov 2015

New combination treatment provides better wound healing compared to SSGs alone

The use of meshed split skin autographs (SSGs) is a standard treatment for large, deep burns. However, serious scarring is often a result. In an effort to improve wound healing and reduce scarring, a team of researchers in The Netherlands tested a treatment technique on patients with serious, deep burns that employed SSGs along with autologous cultured proliferating epidermal cells (ECs) compared to SSGs alone.

3 Nov 2015

TSRI scientists awarded NIH grant to investigate molecular machinery involved in cancer metastasis

Cancer metastasis occurs when tumor cells escape from a primary tumor, via the blood stream, and establish tumors in secondary locations. When the metastases are found in distant tissues and organs, doctors call this stage IV cancer, and the survival rate is low.

3 Nov 2015

CureVac raises €100M to enable rapid expansion of mRNA development platform, clinical-stage pipeline

CureVac, a clinical-stage biopharmaceutical company pioneering the field of mRNA-based technology, today announces that it has raised about $110 million (€100 million) to enable accelerated expansion of its industry-leading messenger RNA (mRNA) development platform and clinical-stage pipeline.

3 Nov 2015

Secret tunnels used by cancer cells can be exploited to deliver drug therapies, suggests new study

A new discovery published in the Nov. 2015 issue of The FASEB Journal shows that cancer cells use previously unknown channels to communicate with one another and with adjacent non-cancerous cells.

3 Nov 2015

Findings suggest potential metabolic pathway against cancer

When cancer cells compete with immune cells for glucose, the cancer wins. As a result, the immune T cells are not healthy and don't have the weapons to kill the cancer.

3 Nov 2015

Rice scientists solve long-standing mystery about hemophilia protein

Rice University scientists have solved a long-standing mystery about where the body stores and deploys blood-clotting factor VIII, a protein that about 80 percent of hemophiliacs cannot produce due to genetic defects.

3 Nov 2015

Inhibiting key enzyme pathways decreases inflammation and frailty in aged mice

Chronic inflammation, closely associated with frailty and age-related diseases, is a hallmark of aging. Mayo Clinic researchers have discovered that inhibiting key enzyme pathways reduces inflammation in human cells in culture dishes and decreases inflammation and frailty in aged mice.

3 Nov 2015

Salk scientists uncover enzyme responsible for suppressing deadly lung cancer

Scientists at the Salk Institute have uncovered a molecule whose mutation leads to the aggressive growth of a common and deadly type of lung cancer in humans.

3 Nov 2015

Discovery offers promising alternative to current therapies for AMD and ROP

A research team led by scientists at Beth Israel Deaconess Medical Center and the University of New Mexico School of Medicine has identified a small molecule that treats animal models of aged macular degeneration (AMD) and retinopathy of prematurity (ROP) by preventing the overgrowth of blood vessels that are characteristic of these two retinal diseases.

3 Nov 2015

Research sheds new light on the fight against tonsil cancer

Researchers at Simon Fraser University and the BC Cancer Agency have developed a groundbreaking method to identify and separate stem cells that reside in the tonsils. Their research, which sheds new light on the fight against oral cancer, is published today in the journal Stem Cell Reports.

3 Nov 2015

Study highlights importance of sex-specific differences in complex biological processes

New research published in the Journal of Leukocyte Biology shows that male and female mice respond differently to inflammation at the cellular level. Specifically, in male mice the spleen acts as a source of white blood cells, while in females this is not the case. This discovery suggests that human studies are necessary to determine if current medical practices, which treat men and women generally the same, should be altered to reflect sex-specific differences.

3 Nov 2015

Researchers examine risk of four common types of ovarian cancer in women with different childbearing patterns

The more children a woman has or whether a woman has had her fallopian tubes cut lowers the risk of different types of ovarian cancer to different levels, according to new research presented at the 2015 National Cancer Research Institute Cancer Conference today (Tuesday).

3 Nov 2015

Researchers identify tumor suppressor genes that drive subset of melanomas

Of the hundreds of genes that can be mutated in a single case of melanoma, only a handful may be true "drivers" of cancer. In research that appeared today in Nature Genetics, a Weizmann Institute of Science team has now revealed one of the drivers of a particularly deadly subset of melanomas - one that is still seeing a rise in new cases. This gene is a newly identified member of a group of genes called tumor suppressor genes.

3 Nov 2015

VA should hold senior officials accountable, says American Legion National Commander

The leader of the nation's largest veterans organization called a senior VA official's concession during a congressional hearing tonight that the department has an accountability problem "one of the understatements of the year."

3 Nov 2015

CPFN, Cure CP raise funds to extend research on cerebral palsy

Will it one day be possible to cure cerebral palsy? Scientists working in a new field of study known as "regenerative medicine" think so. But support is needed to further the research, according to two non-profit organizations founded by parents of children with CP.

2 Nov 2015