Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

UK government announces deals to secure two new COVID-19 treatments

Thousands of vulnerable patients could be taking ground-breaking COVID-19 antivirals this winter after the government announced deals to secure two new treatments.

20 Oct 2021

Scientists search for cause of mysterious covid-related inflammation in children

Like most other kids with covid, Dante and Michael DeMaino seemed to have no serious symptoms.

20 Oct 2021

Safety and oral immunogenicity of a VSV-derived mucosal vaccine against SARS-CoV-2

A team of researchers exploited the known tropism of vesicular stomatitis virus to develop an oral vaccine that expresses the immunogenic SARS-CoV-2 spike glycoprotein in the oral mucosa.

20 Oct 2021

Long-term predictions of immunity after two doses of mRNA vaccine

Researchers from York University has investigated the long-term protection of two mRNA vaccines.

20 Oct 2021

BNT162b2 mRNA COVID-19 vaccine-induced antibodies wane over six month period

Researchers have been investigating the response of antibodies created against SARS-CoV-2 by the Pfizer-BioNTech six months after vaccination.

20 Oct 2021

An investigation of three SARS-CoV-2 mRNA doses in multiple sclerosis vaccine non-responders

A clinical study by a team of scientists from Norway aimed to assess the immunogenicity and safety of a third dose of COVID-19 mRNA vaccine in MS patients treated with anti-CD20 therapy or fingolimod. A preprint version of the study, which is yet to undergo peer review, is available on the medRxiv* server.

20 Oct 2021

Microscopy-based high content platform for SARS-CoV-2 serological screening

A new study published on the medRxiv* preprint server used automated high content immunofluorescence microscopy (AHCIM) to assess the viability of such an approach to detect humoral immune responses against SARS-CoV-2 proteins.

20 Oct 2021

Regular testing of SARS-CoV-2 positive vaccinated HCWs may reduce need for long quarantines

A new study published in the journal Annals of Internal Medicine conducted systematic surveillance involving 2,397 HCWs who were fully vaccinated with the Pfizer-BioNTech BNT162 vaccine at the ASST Settelaghi hospitals, Italy, in February 2021.

19 Oct 2021

COVID-19 vaccine breakthrough infections among immunocompromised individuals

A study of breakthrough infections in immunocompromised people following two doses of the Pfizer/BioNTech vaccine against SARS-CoV-2 concluded that immunocompromised people would be best served with a third dose of the vaccine for better protection.

19 Oct 2021

Factors impacting mental health and wellbeing of long covid patients

A new preprint deals with the mental baggage accompanying this condition, often termed “long covid.”

19 Oct 2021

Phase 2 trial shows COVID-19 recombinant protein vaccine elicits promising immunogenicity responses

Researchers performed a large-scale, double-blind, placebo-controlled phase two trial to assess the efficacy, safety, and immune response elicited from vaccination with MVC-COV1901.

19 Oct 2021

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

In a recent study published in the journal PLOS Pathogens, scientists showed that nasal administration of a single-domain antibody (VHH), named K-874A, brought about inhibition of SARS-CoV-2 titers in infected lungs of Syrian hamsters.

19 Oct 2021

SARS-CoV-2 antibodies detected in breast milk of vaccinated mothers

Now, a new medRxiv* preprint study finds mothers vaccinated either one of the messenger RNA (mRNA) vaccines transferred neutralizing antibodies and cytokines, including interferon-gamma (IFNγ), to a breastfeeding child. Additionally, the humoral response in breastmilk was effective in neutralizing four variants of concern.

18 Oct 2021

Many people's T-cells recognize the same components of SARS-CoV-2

A new study published on the bioRxiv* preprint aimed to identify highly immunoprevalent CD8 T-cell epitopes specific to SARS-CoV-2 that are confirmed to be endogenously processed and presented on frequently expressed HLA alleles.

18 Oct 2021

Modelling suggests fall in acute admissions with mass COVID-19 vaccinations

A new study explores the utility of modeling the impact of mass vaccination on the number of hospital beds occupied by acute COVID-19 cases.

18 Oct 2021

Factors contributing to a weak antibody response to the Pfizer COVID-19 vaccine

A new study discusses risk factors for the failure of seroconversion following full vaccination with the COVID-19 Pfizer vaccine.

18 Oct 2021

Study identifies the role of a key cell receptor in efferocytosis after ischemic stroke

It's clear that taking out the trash is an essential process in maintaining a clean and tidy home. But did you know that your body has a similar process for waste removal in which damaged cells are "thrown out"? A research team in Japan has recently shed new light on the dynamics of this process—termed efferocytosis—following ischemic stroke.

18 Oct 2021

Antibody News and Research

Further Reading

UK government announces deals to secure two new COVID-19 treatments

Scientists search for cause of mysterious covid-related inflammation in children

Safety and oral immunogenicity of a VSV-derived mucosal vaccine against SARS-CoV-2

Long-term predictions of immunity after two doses of mRNA vaccine

BNT162b2 mRNA COVID-19 vaccine-induced antibodies wane over six month period

An investigation of three SARS-CoV-2 mRNA doses in multiple sclerosis vaccine non-responders

Microscopy-based high content platform for SARS-CoV-2 serological screening

Regular testing of SARS-CoV-2 positive vaccinated HCWs may reduce need for long quarantines

COVID-19 vaccine breakthrough infections among immunocompromised individuals

Factors impacting mental health and wellbeing of long covid patients

Phase 2 trial shows COVID-19 recombinant protein vaccine elicits promising immunogenicity responses

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

SARS-CoV-2 antibodies detected in breast milk of vaccinated mothers

Many people's T-cells recognize the same components of SARS-CoV-2

Modelling suggests fall in acute admissions with mass COVID-19 vaccinations

Factors contributing to a weak antibody response to the Pfizer COVID-19 vaccine

Study identifies the role of a key cell receptor in efferocytosis after ischemic stroke

Novel combination therapy identified for the brain metastases of breast cancer

Study shows enhanced immunogenicity of heterologous boosting strategy in individuals primed with J&J vaccine

Study assesses T-cell responses directed against highly conserved regions of SARS-CoV-2

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