Cell News and Research

RSS

Sleep deprivation can impact outcome of stem cell transplantation, study finds

Drowsy mice make poor stem cell donors, according to a new study by researchers at the Stanford University School of Medicine.

15 Oct 2015

Neutrophils kill invading microorganisms, starve microbes to death

The most frequent immune cells in the human blood, so-called neutrophils, efficiently kill invading microorganisms and slowly starve microbes to death by removing crucial trace elements. This is shown by researchers from Umeå University in Sweden in a study published in a special issue of Metallomics.

15 Oct 2015

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Kessler researchers assessed moderate to severe traumatic brain injury (TBI) for frontal behavioral syndromes and cognitive function. Their finding suggest that adding the Frontal Systems Behavior Scale to neuropsychological assessment may yield useful information about the behavioral sequelae of TBI.

15 Oct 2015

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

Gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa, according to research funded by the National Eye Institute (NEI), part of the National Institutes of Health. The findings contribute to the groundwork needed to move gene therapy forward into clinical trials for people with the blinding eye disorder, for which there is currently no cure.

15 Oct 2015

UTHealth biochemists expose structures of IP3R calcium channels

Calcium is a crucial element in the body that controls thought, movement and other bodily functions. These events are directed by specialized proteins called ion channels that allow the flow of calcium ions in and out of cells and among cell compartments. For years, scientists have been unsure how calcium ion channels function.

15 Oct 2015

CWRU investigator receives $2.82 million NIH grant to make stealth bombs for brain cancer treatment

A Case Western Reserve University researcher has received a 5-year, $2.82 million National Institutes of Health grant to make, in essence, stealth bombs that slip past the brain's defenses to attack an incurable form of cancer.

15 Oct 2015

New blood test could help pair cancer patients with suitable therapy for their disease

CANCER RESEARCH UK-funded scientists have developed a blood test that could help pair cancer patients with the most suitable therapy for their disease and then track the tumour's progress to see if the treatment is working, according to research published today (Thursday) in Clinical Cancer Research.

15 Oct 2015

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

An international research team led by scientists at the University of New Mexico Cancer Center discovered and developed a novel ligand peptide-mimic that inhibits abnormal overgrowth of blood vessels in retinal diseases and tumors. The discovery could lead to new drugs that keep cancers from growing. The team published a paper in the journal Science Translational Medicine.

15 Oct 2015

TxCell reviews its manufacturing strategy to focus on R&D and strategic partnerships - its core, high added value businesses

TxCell SA, a biotechnology company developing innovative, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that it is operating a strategic review that should result in the outsourcing of all existing and future clinical and commercial manufacturing operations to contract manufacturing organizations (CMOs).

15 Oct 2015

Different Crohn's disease treatments affect children's gut microbes in distinct ways

Different treatments for Crohn's disease in children affects their gut mi-crobes in distinct ways, which has implications for future development of microbial-targeted therapies for these patients, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Oct 2015

BREVENA Laboratories receives National Eczema Association's Seal of Acceptance award for Restorative Skin Balm

BREVENA Laboratories, LLC, a luxury skincare cosmetics company that combines beauty and advanced medical technology, announces that the National Eczema Association has awarded the Seal of Acceptance to the brand's Restorative Skin Balm.

15 Oct 2015

OncoSec reports net loss of $6.5 million for fourth quarter of fiscal 2015

OncoSec Medical Incorporated, a company developing DNA-based intratumoral cancer immunotherapies, today announced financial results for the fourth quarter and fiscal year ended July 31, 2015.

15 Oct 2015

Notch activation determines signals necessary to generate hematopoietic stem cells in laboratory

An international study led by researchers from IMIM (Hospital del Mar Medical Research Institute) published in the journal Nature Communications has revealed that the intensity or efficiency of the activation of a protein called Notch, which is involved in the different phases of embryonic development, determines the fate of cells, i.e. if cells will form the aorta artery or blood (hematopoietic) stem cells. For artery cells, many Notch molecules need to be activated, whereas for hematopoietic cells many fewer are needed.

14 Oct 2015

Researchers identify molecular switch that can avoid inflammation

Our immune system is vital to us and can sometimes overreact causing chronic illnesses, such as for instance rheumatism and allergy. Now, researchers from Umeå University and University of Gothenburg have identified a molecular switch - MYSM1 - that can suppress such an overreaction and avoid inflammation.

14 Oct 2015

New hope for patients with Duchenne muscular dystrophy

New hope for Duchenne muscular dystrophy (DMD) patients. A mouse genetic study in PLoS Medicine reports that targeting the P2RX7 gene, a purinoreceptor, may halt the progression of DMD.

14 Oct 2015

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

In humans, much is already known about the impact of maternal undernutrition during pregnancy, and its impact on growth, development and disease throughout the life course. However, until recently little was known about the effects of the nutritional environment around the time of conception.

14 Oct 2015

Researchers come up with new design for a better liposome

Using computational modeling, researchers at Carnegie Mellon University, the Colorado School of Mines and the University of California, Davis have come up with a design for a better liposome. Their findings, while theoretical, could provide the basis for efficiently constructing new vehicles for nanodrug delivery.

14 Oct 2015

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study.

14 Oct 2015

CU Cancer Center study reports 'robust antitumor activity' of TAK-733 drug in mouse models of colorectal cancer

A University of Colorado Cancer Center study recently published online ahead of print in the journal Oncotarget reports "robust antitumor activity" of the drug TAK-733 in cells and mouse models of colorectal cancer.

14 Oct 2015

Researchers find significant link between breast cancer and nutrition, explore new preventative treatment

Researchers at Sydney’s Centenary Institute are working on a new treatment aimed at “starving” breast cancer cells, following the discovery of a significant link between breast cancer and nutrition.

14 Oct 2015

Cell News and Research

Sleep deprivation can impact outcome of stem cell transplantation, study finds

Neutrophils kill invading microorganisms, starve microbes to death

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

UTHealth biochemists expose structures of IP3R calcium channels

CWRU investigator receives $2.82 million NIH grant to make stealth bombs for brain cancer treatment

New blood test could help pair cancer patients with suitable therapy for their disease

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

TxCell reviews its manufacturing strategy to focus on R&D and strategic partnerships - its core, high added value businesses

Different Crohn's disease treatments affect children's gut microbes in distinct ways

BREVENA Laboratories receives National Eczema Association's Seal of Acceptance award for Restorative Skin Balm

OncoSec reports net loss of $6.5 million for fourth quarter of fiscal 2015

Notch activation determines signals necessary to generate hematopoietic stem cells in laboratory

Researchers identify molecular switch that can avoid inflammation

New hope for patients with Duchenne muscular dystrophy

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

Researchers come up with new design for a better liposome

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

CU Cancer Center study reports 'robust antitumor activity' of TAK-733 drug in mouse models of colorectal cancer

Researchers find significant link between breast cancer and nutrition, explore new preventative treatment

Improve fermentation and cell culture performance with real-time gas analysis eBook

Latest eBooks

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence