Addiction News and Research

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NIDA awards $1.4M grant to aid development of formal addiction medicine training programs

Boston Medical Center physician Jeffrey Samet, MD, chief, section of general internal medicine, in collaboration with Co-Principal Investigator, Patrick O'Connor, MD, chief section of general internal medicine at Yale School of Medicine, were awarded a five-year, $1.4 million grant from the National Institute On Drug Abuse to aid the development of formal addiction medicine training programs.

3 Apr 2012

TLR4/MD-2 protein complex triggers morphine-induced inflammation

A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for improving the efficacy of the widely used painkiller while decreasing its abuse potential.

3 Apr 2012

Health reform means ER use jumps in Colo.; Calif. insurance premiums rise; Ore. waits to see who wants in on coordinated care

Even people who just got health insurance use the emergency departments to access their care, according to a new study by University of Colorado School of Medicine researchers. It's not just people who lost insurance or people living long without it, the researchers note -- any change in health insurance status, whether positive or negative, tends to send people to the ER because they don't know where else to go.

3 Apr 2012

Nektar commences dosing in NKTR-192 Phase 1 clinical study for treatment of acute pain

Nektar Therapeutics announced today that the first subjects were dosed last week in a Phase 1 clinical study to evaluate the pharmacokinetics and safety of NKTR-192, the company's novel short-acting mu-opioid analgesic candidate.

2 Apr 2012

FDA releases two draft guidance documents to help fight tobacco epidemic

Today the U.S. Food and Drug Administration (FDA) released two separate draft guidance documents to help fight the tobacco epidemic and stop children from using tobacco. The draft guidance documents implement provisions of the Family Smoking Prevention and Tobacco Control Act that will ultimately provide the public with previously unknown information about the chemicals in tobacco products and help prevent misleading marketing about the risks associated with tobacco products.

31 Mar 2012

New strategy to ensure that GPs advise heavy drinkers to cut down

The new UK alcohol strategy includes a plan to ensure that General Practitioners (GPs) advise heavy drinkers to cut down.

29 Mar 2012

Scientists explore number of strategies to prevent anesthesia-induced injury in infants

Recent clinical studies have shown that general anesthesia can be harmful to infants, presenting a dilemma for both doctors and parents. But new research at Wake Forest Baptist Medical Center may point the way to treatment options that protect very young children against the adverse effects of anesthesia.

29 Mar 2012

Online gambling may increase risk of alcohol and cannabis use

With the click of a mouse or touch of a mobile phone screen - in pyjamas or jeans - gambling is now at our fingertips 24/7 with Internet play. With this increased access to gambling, are online gamblers more prone to risky behaviours than offline gamblers?

28 Mar 2012

Nanoscale sensor can conduct individual DNA sequencing

Researchers have devised a nanoscale sensor to electronically read the sequence of a single DNA molecule, a technique that is fast and inexpensive and could make DNA sequencing widely available.

27 Mar 2012

DBS allows surgeons to control tremors with brain 'pacemaker'

For nearly 30 years, Tom Rogers' left hand would shake when he tried to use it, making even simple tasks such as drinking a glass of water, writing a check, or making a sandwich challenging. The tremor eventually became so disruptive that he lost use of his dominant hand. Rogers sought care and learned that his tremor was a symptom of Parkinson's disease, yet felt he was suffering from something different.

27 Mar 2012

Additional help does not improve success rates for smokers trying to quit

A major research trial to test whether extra support for smokers calling an NHS quitline - on top of what is already offered by the service - has found the additional help does not improve success rates for quitting the habit.

26 Mar 2012

FMBFarma granted exclusive rights to market Ampio's Zertane for PE in Brazil

Ampio Pharmaceuticals, Inc., a company that discovers and develops new uses for previously approved drugs and new molecular entities, and FBM Industria Farmaceutica Ltda, a member of the HOSPFAR Group that manufactures, imports and distributes pharmaceuticals in Brazil, today announced a license and distribution agreement providing FMBFarma exclusive rights to market Zertane in Brazil for the treatment of premature ejaculation.

22 Mar 2012

Scientists reveal first-ever glimpse of complete kappa opioid receptor structure

At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body.

22 Mar 2012

Smoking may restore self-control

Researchers at Moffitt Cancer Center in Tampa, Fla., have found that when they deplete a smoker's self control, smoking a cigarette may restore self-control.

20 Mar 2012

Heptares exercises exclusive option to license new A2A antagonist for CNS disorders

Heptares Therapeutics, the leading GPCR drug discovery company, announces that an operating company of Shire PLC, the global specialty biopharmaceutical company, has exercised its exclusive option to license a novel adenosine A2A antagonist discovered by Heptares that is currently in preclinical development.

20 Mar 2012

Sexually rejected male fruit flies binge on alcohol more than sexually satisfied peers: Study

Male fruit flies whose sexual advances are rejected by females, turn to alcohol finds a new study. Scientists at the University of California, San Francisco discovered that rejected male flies have a tiny molecule in their brain that pushes them to drink far more than their sexually satisfied counterparts. The levels of the molecule, neuropeptide F, were higher in sexually satisfied males than in those who got no sex, leading scientists to speculate that their work could shed light on brain mechanisms behind human addiction. A similar human molecule - neuropeptide Y - may also link social triggers to behaviors such as heavy drinking and drug abuse, according to the study published in Science journal.

18 Mar 2012

Study identifies primary care skills and competencies in opioid risk management

Primary care physicians are faced with treating a large proportion of chronic pain patients, but many do not often have specific training in the assessment and management of chronic pain, including the use of opioid medications for chronic pain management.

17 Mar 2012

Neuropeptide F in the fly's brain governs behavior linked with addiction

Sexually deprived male fruit flies exhibit a pattern of behavior that seems ripped from the pages of a sad-sack Raymond Carver story: when female fruit flies reject their sexual advances, the males are driven to excessive alcohol consumption, drinking far more than comparable, sexually satisfied male flies.

16 Mar 2012

AT-1001 shows promise in treating drug addiction

In preclinical studies, researchers at SRI International and Astraea Therapeutics have recently evaluated the role of a new drug receptor target that shows promise for the treatment of drug addiction.

15 Mar 2012

Scientists identify new compound that quickly kills HCC cells

Scientists have identified a new compound that rapidly kills hepatocellular carcinoma (HCC) cells, the most common form of liver cancer and fifth most common cancer worldwide, while sparing healthy tissue.

15 Mar 2012

Addiction News and Research

NIDA awards $1.4M grant to aid development of formal addiction medicine training programs

TLR4/MD-2 protein complex triggers morphine-induced inflammation

Health reform means ER use jumps in Colo.; Calif. insurance premiums rise; Ore. waits to see who wants in on coordinated care

Nektar commences dosing in NKTR-192 Phase 1 clinical study for treatment of acute pain

FDA releases two draft guidance documents to help fight tobacco epidemic

New strategy to ensure that GPs advise heavy drinkers to cut down

Scientists explore number of strategies to prevent anesthesia-induced injury in infants

Online gambling may increase risk of alcohol and cannabis use

Nanoscale sensor can conduct individual DNA sequencing

DBS allows surgeons to control tremors with brain 'pacemaker'

Additional help does not improve success rates for smokers trying to quit

FMBFarma granted exclusive rights to market Ampio's Zertane for PE in Brazil

Scientists reveal first-ever glimpse of complete kappa opioid receptor structure

Smoking may restore self-control

Heptares exercises exclusive option to license new A2A antagonist for CNS disorders

Sexually rejected male fruit flies binge on alcohol more than sexually satisfied peers: Study

Study identifies primary care skills and competencies in opioid risk management

Neuropeptide F in the fly's brain governs behavior linked with addiction

AT-1001 shows promise in treating drug addiction

Scientists identify new compound that quickly kills HCC cells

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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