Protein C News and Research

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Possible new therapeutic target for pancreatic cancer

A possible new therapeutic target for pancreatic cancer, the most lethal form of human cancer, has been identified in the proteins whose DNA recipe comes from gene, "Seven-In-Absentia," according to researchers at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

14 Dec 2008

Discovery of gene mutation that appears to help prevent heart disease

Researchers at the University of Maryland School of Medicine in Baltimore have discovered a novel gene mutation among the Old Order Amish population that significantly reduces the level of triglycerides in the blood and appears to help prevent cardiovascular disease.

12 Dec 2008

Numbing drugs can have profound and long-term negative effects

A large proteomics study on the brains of newborn mice provides more evidence that numbing drugs often used in obstetric or pediatric medicine can have profound and long-term negative effects, even after minimal exposure.

12 Dec 2008

Novavax announces positive results in trial of seasonal influenza VLP (trivalent) vaccine candidate

Novavax, Inc. has announced favorable results from a Phase IIa human clinical trial of its seasonal influenza VLP (trivalent) vaccine candidate.

12 Dec 2008

New cause of atrial fibrillation found

A new study shows that atrial fibrillation--the most common form of sustained heart arrhythmia--can be caused in an unexpected way.

12 Dec 2008

Food you eat can immediately impact cognitive behavior

A new study from the psychology department at Tufts University shows that when dieters eliminate carbohydrates from their meals, they performed more poorly on memory-based tasks than when they reduce calories, but maintain carbohydrates.

12 Dec 2008

Heart regenerates after infarction

Up until today scientists assumed that the adult heart is unable to regenerate. Now, researchers and cardiologists from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and the Charité - Universitätsmedizin Berlin (Germany) have been able to show that this dogma no longer holds true.

12 Dec 2008

Entomologists look for Lyme disease answers in tick saliva

In research that could mitigate the spread of Lyme disease, Kansas State University entomologists are looking for answers in tick saliva.

12 Dec 2008

Researchers capture never before seen undulations of "dancing chromosomes"

The rhythm of life may beat far deeper than anyone previously thought. And it may gyrate and pulse in a way that rivals the sensuous choreography of "Dirty Dancing."

12 Dec 2008

Researchers create tiny, implantable device that captures and kills cancer cells in the bloodstream

In a new tactic in the fight against cancer, Cornell University researcher Michael King has developed what he calls a lethal "lint brush" for the blood -- a tiny, implantable device that captures and kills cancer cells in the bloodstream before they spread through the body.

12 Dec 2008

Vaxfectin-formulated H5N1 pandemic influenza achieves T-cell responses and cross-clade reactivity in humans

Vical Incorporated has announced that the company's Vaxfectin-formulated H5N1 pandemic influenza DNA vaccines induced T-cell responses against a matching strain of influenza virus and demonstrated cross-clade antibody responses against a different strain in a Phase 1 clinical trial.

11 Dec 2008

Genetic links found between type 1 diabetes and celiac disease

Type 1 (juvenile) diabetes and celiac disease appear to share a common genetic origin, scientists at the University of Cambridge and Barts and The London School of Medicine and Dentistry, have confirmed.

10 Dec 2008

RNA interference can facilitate vaccine development

Pharmaceutical companies and universities are racing to develop drugs that use the gene silencing mechanism known as RNA interference to treat a host of diseases.

10 Dec 2008

Studies on imaging and tracking transplanted cells

Successfully monitoring the distribution and fate of transplanted stem cells through imaging and subsequent tracking would aid clinicians in their ability to evaluate the efficacy of transplanted cells.

10 Dec 2008

Scans show immune cells intercepting parasites

Researchers may have identified one of the body's earliest responses to a group of parasites that causes illness in developing nations.

10 Dec 2008

New technique may provide quicker and easier way of developing protein-based drugs

Research by a Michigan State University chemist could eventually lead to a quicker and easier way of developing protein-based drugs that are key to treating a number of diseases, including cancer, diabetes and hepatitis.

10 Dec 2008

Protein FKBP12 provides new insights into understanding autism

Researchers at New York University's Center for Neural Science and the Baylor College of Medicine have identified a protein that when removed from mice results in behaviors that are akin to those with autism and obsessive-compulsive disorders.

10 Dec 2008

New research points to possible treatment for Lou Gehrig's disease

There are many ways to die, but amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease must be one of the worst.

10 Dec 2008

Rosiglitazone shows potential for treating focal segmental glomerulosclerosis

The antidiabetes drug rosiglitazone may have the potential to protect kidney function in patients with a condition called focal segmental glomerulosclerosis (FSGS), according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN).

10 Dec 2008

Decreased levels of binding gene affect memory and behavior

Reducing the activity of a gene called FKBP12 in the brains of mice affected neuron-to-neuron communication (synapse) and increased both fearful memory and obsessive behavior, indicating the gene could provide a target for drugs to treat diseases such as autism spectrum disorder, obsessive-compulsive disease and others, said researchers from Baylor College of Medicine in Houston in a report in the current issue of the journal Neuron.

10 Dec 2008