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Marina Cavazzana, Adrian J. Thrasher honored with Pioneer Award for gene therapy

Marina Cavazzana, MD, PhD, Paris Descartes University, France and Adrian J. Thrasher, MD, PhD, University College London Institute of Child Health, UK, have been honored with the Pioneer Award for basic and clinical gene therapy for immunodeficiency disorders.

25 Mar 2014

Scientist receives $275,000 grant to study human papillomavirus that causes head and neck cancer

Basic scientists focus on understanding how things work, so most don't get the chance to directly impact other people's lives. That's why Michelle Ozbun, PhD, is very excited about her recent grant to study human papillomavirus.

25 Mar 2014

More skin cancer awareness needed for minorities, says Henry Ford Hospital dermatologist

More awareness about skin cancer is needed for minorities because they believe they are at low risk of developing it, says Henry Ford Hospital dermatologist Diane Jackson-Richards, M.D.

25 Mar 2014

Treatment with natalizumab in patients with MS appears linked with JC virus infection

Treatment with natalizumab in patients with multiple sclerosis (MS) appears linked with JC virus (JCV) infection, which can lead to a rare and often fatal demyelinating disease of the central nervous system called progressive multifocal leukoencephalopathy (PML) that destroys the myelin that protects nerve cells.

25 Mar 2014

Cell-free DNA analysis allows noninvasive tumour genotype monitoring

Noninvasive tumour genotyping using cell-free plasma DNA analysis is feasible, say US researchers who believe the technique will aid patient diagnosis and monitoring.

24 Mar 2014

Rexahn provides updates on clinical development programs, reports full-year 2013 financial results

Rexahn Pharmaceuticals, Inc. a clinical stage biopharmaceutical company developing best-in-class therapeutics for the treatment of cancer, is providing an overview of its three clinical development programs and Year for the year ended December 31, 2013.

24 Mar 2014

Patrys provides update on development programme for anti-cancer product, PAT-LM1

Patrys Limited, a clinical stage biotechnology company, is pleased to provide an update on the development programme for anti-cancer product, PAT-LM1.

24 Mar 2014

Study examines events that lead to sepsis by Streptococcus pneumoniae

An international team of academics, including Professor Marco Oggioni from the University of Leicester's Department of Genetics, has studied how localised infections can turn into the dangerous systematic disease sepsis - and has identified for the first time through genetic evidence that a single bacteria could be the cause.

24 Mar 2014

Cumulative amount of specific gene products affects changes in cell fate, say researchers

Johns Hopkins biologists have discovered that when biological signals hit cells in rhythmic waves, the magnitude of the cells' response can depend on the number of signaling cycles — not their strength or duration. Because such so-called “oscillating signaling cycles” are common in many biological systems, the scientists expect their findings in single-celled organisms to help explain the molecular workings of phenomena such as tissue and organ formation and fundamental forms of learning.

24 Mar 2014

Research findings may be beneficial for creation of purer HSC lines for clinical treatments

Hematopoietic stem cells are now routinely used to treat patients with cancers and other disorders of the blood and immune systems, but researchers knew little about the progenitor cells that give rise to them during embryonic development.

24 Mar 2014

Drugs fail to "wake up" dormant reservoirs of HIV inside immune system T cells

Scientists at Johns Hopkins report that compounds they hoped would "wake up" dormant reservoirs of HIV inside immune system T cells - a strategy designed to reverse latency and make the cells vulnerable to destruction - have failed to do so in laboratory tests of such white blood cells taken directly from patients infected with HIV.

24 Mar 2014

New way to make large concentrations of skeletal muscle cells from human stem cells

As stem cells continue their gradual transition from the lab to the clinic, a research group at the University of Wisconsin-Madison has discovered a new way to make large concentrations of skeletal muscle cells and muscle progenitors from human stem cells.

24 Mar 2014

New insight into germline EGFR T790M mutation in familial non-small cell lung cancer

Two studies are providing new insight into germline epidermal growth factor receptor (EGFR) T790M mutation in familial non-small cell lung cancer (NSCLC). The findings suggest the need for tailored approaches for early detection and treatment, as well as for genetic testing to identify carriers.

24 Mar 2014

State highlights: Ark. court reverses $1.2B Medicaid drug judgment; Fla. officials overhauling child welfare agency

The Arkansas Supreme Court reversed a $1.2 billion judgment against Johnson & Johnson on Thursday, finding that the state attorney general erred by suing under a law that applied to health care facilities, not drug companies. The judgment, one of the largest in history for a state fraud case, was imposed in 2012 after a jury concluded that Johnson & Johnson had improperly marketed and concealed the risks of Risperdal, an antipsychotic drug (Thomas, 3/2).

24 Mar 2014

Scientists develop unique cells to repair patient's defective and diseased bladder

For the first time, scientists have succeeded in coaxing laboratory cultures of human stem cells to develop into the specialized, unique cells needed to repair a patient's defective or diseased bladder.

24 Mar 2014

Investigators find group of drugs to treat heart attacks and cancer metastasis

Massachusetts General Hospital (MGH) investigators may have found a way to solve a problem that has plagued a group of drugs called ligand-mimicking integrin inhibitors, which have the potential to treat conditions ranging from heart attacks to cancer metastasis.

24 Mar 2014

Obama presses campaign for health law enrollment

The president continues his many media appearances to help draw attention to the enrollment deadline at the end of March. Meanwhile, a new Pew poll finds that younger Americans are somewhat more interested in the law but support among Hispanics has dropped.

24 Mar 2014

Rare abnormality in chromosomes increases risk of rare childhood leukaemia

Researchers have found that people born with a rare abnormality of their chromosomes have a 2,700-fold increased risk of a rare childhood leukaemia. In this abnormality, two specific chromosomes are fused together but become prone to catastrophic shattering.

24 Mar 2014

Researchers uncover cause of rare type of ovarian cancer that strikes girls and young women

The cause of a rare type of ovarian cancer that most often strikes girls and young women has been uncovered by an international research team led by the Translational Genomics Research Institute, according to a study published online today by the renowned scientific journal, Nature Genetics.

23 Mar 2014

15 mm margins cut NSCLC local recurrence risk after wedge resection

Increasing margin distance up to 15 mm significantly decreases the risk of local recurrence among patients undergoing wedge resection for early-stage, non-small-cell lung cancer, US researchers report.

21 Mar 2014

B Cell News and Research

Marina Cavazzana, Adrian J. Thrasher honored with Pioneer Award for gene therapy

Scientist receives $275,000 grant to study human papillomavirus that causes head and neck cancer

More skin cancer awareness needed for minorities, says Henry Ford Hospital dermatologist

Treatment with natalizumab in patients with MS appears linked with JC virus infection

Cell-free DNA analysis allows noninvasive tumour genotype monitoring

Rexahn provides updates on clinical development programs, reports full-year 2013 financial results

Patrys provides update on development programme for anti-cancer product, PAT-LM1

Study examines events that lead to sepsis by Streptococcus pneumoniae

Cumulative amount of specific gene products affects changes in cell fate, say researchers

Research findings may be beneficial for creation of purer HSC lines for clinical treatments

Drugs fail to "wake up" dormant reservoirs of HIV inside immune system T cells

New way to make large concentrations of skeletal muscle cells from human stem cells

New insight into germline EGFR T790M mutation in familial non-small cell lung cancer

State highlights: Ark. court reverses $1.2B Medicaid drug judgment; Fla. officials overhauling child welfare agency

Scientists develop unique cells to repair patient's defective and diseased bladder

Investigators find group of drugs to treat heart attacks and cancer metastasis

Obama presses campaign for health law enrollment

Rare abnormality in chromosomes increases risk of rare childhood leukaemia

Researchers uncover cause of rare type of ovarian cancer that strikes girls and young women

15 mm margins cut NSCLC local recurrence risk after wedge resection

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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