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Research shows why microgravity leads to muscle loss

People can easily feel the presence - or absence - of gravity. Our individual cells actually may be able to sense gravity, too, and that ability could play a role in the loss of muscle that occurs when humans spend time in space.

1 Oct 2015

Brodalumab therapy achieves 100% reduction in psoriasis symptoms

An experimental, biologic treatment, brodalumab, achieved 100 percent reduction in psoriasis symptoms in twice as many patients as a second, commonly used treatment, according to the results of a multicenter clinical trial led by Mount Sinai researchers and published online today in the New England Journal of Medicine.

1 Oct 2015

European Food Venture Forum held in Aarhus, Denmark

You probably don't think about it, but when you go to your local supermarket to buy e.g. yoghurt, huge efforts have been made to allow you to choose this particular product.

1 Oct 2015

UH researcher investigates two new avenues for detection, treatment of prostate cancer

Prostate cancer is the most commonly diagnosed malignancy and second leading cause of cancer-related deaths among men in the U.S. The challenge with prostate cancer is that the standard treatment methods in the advanced stage of the disease lose effectiveness after about one to two years, leading to recurrence and, ultimately, death. A University of Houston researcher and his team are working to change that.

30 Sep 2015

Aspen Park Pharmaceuticals acquires worldwide rights to APP-111 therapy from Ohio State University

Aspen Park Pharmaceuticals, Inc., a private company, today announced that it has acquired worldwide rights from The Ohio State University, through the Ohio State Innovation Foundation, to APP-111. APP-111 is a first-in-class oral, antitubulin targeting agent for the potential treatment for the form of castration resistant prostate cancer that does not respond or becomes resistant to currently available androgen receptor antagonists like XTANDI (enzalutamide) and testosterone reducing agents like ZYTIGA (abiraterone acetate and prednisone).

30 Sep 2015

Unlocking the genes behind antibiotic resistance: an interview with Professor Romesberg

Bacteria are very, very diverse. This is why their susceptibility to different antibiotics can be very different. It also makes the tools they have to evolve resistance in many cases different.

30 Sep 2015

OncoGenex meets target enrollment in apatorsen Phase 2 trial

OncoGenex Pharmaceuticals, Inc. announced today that Borealis-2, an investigator-sponsored, randomized Phase 2 trial, has met its target enrollment of 200 patients. Designed to evaluate apatorsen in combination with docetaxel in patients with advanced or metastatic bladder cancer who have disease progression following first-line platinum-based chemotherapy, Borealis-2 is sponsored by Hoosier Oncology Group and is being conducted at 27 sites across the United States.

30 Sep 2015

Researchers reveal how varied genetic background influences tumour differences

Researchers from Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumour type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.

30 Sep 2015

Novel portable device counts white blood cells in real time

A novel way to count white blood cells without a blood test, simply by applying a small device on the fingertip, is being developed by a team of young bioengineers. The technology, that combines an optical sensor with algorithms, has already three prototypes on the go and is specially designed to be used on chemotherapy patients, who could know their immune system levels in real time. It could also serve to detect serious infections.

30 Sep 2015

Engineering students from across the globe can now compete in 2015 Knovel Academic Challenge

Elsevier, a world-leading provider of scientific, technical and medical information products and services, has launched the10th Knovel Academic Challenge; engineering students from across the globe can now sign up to register and compete for weekly prizes.

30 Sep 2015

AMO Pharma raises $25 million in private equity financing

AMO Pharma Limited, a privately held biopharmaceutical company focusing on debilitating diseases with limited or no treatment options, announced today that the company has raised $25 million in private equity financing from Woodford Investment Management.

30 Sep 2015

New study finds that serum miRNA profiles change as myeloma progresses

Virtually all patients who develop myeloma have an asymptomatic disease called monoclonal gammopathy of undetermined significance (MGUS) in the years before the onset of myeloma. The five-year relative survival rate for myeloma is 69% for patients diagnosed with stage I or localized disease, compared with 45% for patients with advanced cancer.

30 Sep 2015

Leading cancer researchers address eight 'big questions'

Leading cancer researchers address eight of the "big questions" facing the field as part of the inaugural issue of Trends in Cancer, published by Cell Press.

30 Sep 2015

Aelan Cell Technologies, Gladstone Institutes partner to study stem cell rejuvenation

Aelan Cell Technologies today announced they have entered into an agreement with the Gladstone Institutes to further its studies on stem cell rejuvenation. This effort will be led by Meenakshi Gaur, Ph.D. of Aelan Cell Technologies and Kathryn Ivey, Ph.D. of the Gladstone Institutes.

30 Sep 2015

Saint Louis University receives NIH grant to investigate development of new drugs to treat bone diseases

David Griggs, Ph.D., director of biology at Saint Louis University's Center for World Health & Medicine, has received a $1 million R01 grant from the National Institutes of Health to investigate the development of what could be a new class of drugs to treat bone diseases.

30 Sep 2015

Glowing protein may replace fiber optic cable as light source in optogenetics research

Optogenetics has taken neuroscience by storm in recent years because the technique allows scientists to study the brain conveniently in animals, activating or inhibiting selected groups of neurons at the flip of a switch. Most often, scientists use a fiber optic cable to deliver light into the brain.

30 Sep 2015

Researchers develop a technique that uses platelet membranes to coat anticancer drugs

Researchers have for the first time developed a technique that coats anticancer drugs in membranes made from a patient's own platelets, allowing the drugs to last longer in the body and attack both primary cancer tumors and the circulating tumor cells that can cause a cancer to metastasize. The work was tested successfully in an animal model.

30 Sep 2015

Intratumoral morphological diversity of breast cancer not related to chromosome aberrations

Intratumor morphological heterogeneity (diversity) of breast cancer is not related to chromosome aberrations. This conclusion was made based on the study of one case with aggressive variant of breast cancer - invasive micropapillary carcinoma by researchers from Tomsk State University, Tomsk Cancer Research Institute, and Institute of Medical Genetics.

30 Sep 2015

Study explores how the human brain contributes to success

Discoveries about how the human brain contributes to our success - both as a species and as individuals - are among the first fruit of projects funded under the National Institutes of Health BRAIN Initiative program as well as the Human Connectome Project.

30 Sep 2015

Researchers unlock structural details of key protein to treat neuromuscular disease

Researchers at Rice University and Baylor College of Medicine have unlocked the structural details of a protein seen as key to treating a neuromuscular disease.

30 Sep 2015

Cell News and Research

Research shows why microgravity leads to muscle loss

Brodalumab therapy achieves 100% reduction in psoriasis symptoms

European Food Venture Forum held in Aarhus, Denmark

UH researcher investigates two new avenues for detection, treatment of prostate cancer

Aspen Park Pharmaceuticals acquires worldwide rights to APP-111 therapy from Ohio State University

Unlocking the genes behind antibiotic resistance: an interview with Professor Romesberg

OncoGenex meets target enrollment in apatorsen Phase 2 trial

Researchers reveal how varied genetic background influences tumour differences

Novel portable device counts white blood cells in real time

Engineering students from across the globe can now compete in 2015 Knovel Academic Challenge

AMO Pharma raises $25 million in private equity financing

New study finds that serum miRNA profiles change as myeloma progresses

Leading cancer researchers address eight 'big questions'

Aelan Cell Technologies, Gladstone Institutes partner to study stem cell rejuvenation

Saint Louis University receives NIH grant to investigate development of new drugs to treat bone diseases

Glowing protein may replace fiber optic cable as light source in optogenetics research

Researchers develop a technique that uses platelet membranes to coat anticancer drugs

Intratumoral morphological diversity of breast cancer not related to chromosome aberrations

Study explores how the human brain contributes to success

Researchers unlock structural details of key protein to treat neuromuscular disease

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