Fatigue News and Research

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Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

The U.S. Food and Drug Administration today approved Imlygic (talimogene laherparepvec), the first FDA-approved oncolytic virus therapy, for the treatment of melanoma lesions in the skin and lymph nodes.

28 Oct 2015

U-M study suggests new therapeutic strategy for treating Duchene muscular dystrophy

Every heart beat and step in our daily lives is dependent on the integrity of muscles and the proteins that keep them strong and free of injury as they contract and relax.

27 Oct 2015

Noninvasive CT scans far better than stress tests at spotting clogged arteries

Results of a head-to-head comparison study led by Johns Hopkins researchers show that noninvasive CT scans of the heart's vessels are far better at spotting clogged arteries that can trigger a heart attack than the commonly prescribed exercise stress that most patients with chest pain undergo.

27 Oct 2015

Reducing depression to a checklist of symptoms may not be useful, new research reveals

How can you tell if someone is depressed? The Diagnostic and Statistical Manual of Mental Disorders (DSM) - the 'bible' of psychiatry - diagnoses depression when patients tick off a certain number of symptoms on the DSM checklist. A large-scale quantitative study coordinated at KU Leuven, Belgium, now shows that some symptoms play a much bigger role than others in driving depression, and that the symptoms listed in DSM may not be the most useful ones.

26 Oct 2015

FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

The U.S. Food and Drug Administration today approved Yondelis (trabectedin), a chemotherapy, for the treatment of specific soft tissue sarcomas (STS) – liposarcoma and leiomyosarcoma – that cannot be removed by surgery (unresectable) or is advanced (metastatic).

24 Oct 2015

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Amgen today announced that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, has adopted a positive opinion recommending that IMLYGIC (talimogene laherparepvec) be granted approval for the treatment of adults with unresectable melanoma that is regionally or distantly metastatic (Stage IIIB, IIIC and IVM1a) with no bone, brain, lung or other visceral disease.

23 Oct 2015

New combination treatment approved by FDA for metastatic pancreatic cancer

The U.S. Food and Drug Administration today approved Onivyde (irinotecan liposome injection), in combination with fluorouracil and leucovorin, to treat patients with advanced (metastatic) pancreatic cancer who have been previously treated with gemcitabine-based chemotherapy.

23 Oct 2015

Early trial results in lung cancer

Results from early phase trials investigating different therapeutic agents in lung cancer patients were presented during the third Presidential Session at the European Cancer Congress in Vienna, Austria. Here we summarise two studies reported at the session.

22 Oct 2015

Lifestyle choices, occupational factors may contribute to crashes among truck drivers

Truck drivers who are frequently fatigued after work, use cell phones while driving, or have an elevated pulse pressure - a potential predictor of cardiovascular disease - may be at increased risk for getting into truck accidents, according to a study by the Rocky Mountain Center for Occupational and Environmental Health at the University of Utah School of Medicine and published in the Journal of Occupational and Environmental Medicine.

22 Oct 2015

Scientists reveal link between depression and paraventricular thalamus

Scientists from the RIKEN Brain Science Institute have shown that a mouse strain with a mutation that leads to dysfunction of mitochondria--the "powerhouses" that provide energy to cells--spontaneously undergo periodic episodes of depression-like behavior that resemble those in human. Through this research, published in Molecular Psychiatry, the scientists uncovered a link between depression and the paraventricular thalamus, a region of the brain not previously tied to depression.

20 Oct 2015

Takeda highlights safety, efficacy of vedolizumab for UC and CD at ACG Annual Scientific Meeting

Takeda Pharmaceuticals, U.S.A., Inc., today announced that data highlighting the efficacy and safety of vedolizumab for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD), will be presented during the 2015 American College of Gastroenterology Annual Scientific Meeting in Honolulu, Hawaii, held on October 16-21.

20 Oct 2015

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

Lexicon Pharmaceuticals, Inc.'s telotristat etiprate, the first oral therapy in development for the treatment of carcinoid syndrome (CS), was associated with patient-reported improvements in social and physical function and emotional well-being according to new exit interview data from the Phase 3 TELESTAR study presented at the 2015 Neuroendocrine Tumor Society Annual Symposium in Austin, Texas.

19 Oct 2015

Sprout announces U.S. availability of Addyi for HSDD treatment in premenopausal women

Sprout Pharmaceuticals, Inc., a division of Valeant Pharmaceuticals North America LLC, announced today that Addyi, a once-daily, non-hormonal pill for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women, is now available in the United States through certified physicians and pharmacies.

19 Oct 2015

BDSI announces FDA approval of BUNAVAIL sNDA for manufacturing specification change

BioDelivery Sciences International, Inc. announced that the U.S. Food and Drug Administration has approved the company's Supplemental New Drug Application (sNDA) for a manufacturing specification change for BUNAVAIL (buprenorphine and naloxone) buccal film (CIII).

15 Oct 2015

New $6.7 million project aims to help kidney dialysis patients live longer

Helping kidney dialysis patients have healthier treatment sessions and longer lives is the goal of a new $6.7 million project at the University of Michigan.

15 Oct 2015

DePuy Synthes Spine launches new all-in-one pedicle screw system to help simplify spinal surgery

DePuy Synthes Spine has introduced the EXPEDIUM VERSE Spinal System, a new all-in-one pedicle screw system. The system enables surgeons to perform multiple spinal correction maneuvers during spinal fusion surgery with a single implant type and fewer instruments, compared to traditional pedicle screw systems.

15 Oct 2015

Fatigue News and Research

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

U-M study suggests new therapeutic strategy for treating Duchene muscular dystrophy

Noninvasive CT scans far better than stress tests at spotting clogged arteries

Reducing depression to a checklist of symptoms may not be useful, new research reveals

FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

New combination treatment approved by FDA for metastatic pancreatic cancer

Early trial results in lung cancer

Lifestyle choices, occupational factors may contribute to crashes among truck drivers

Scientists reveal link between depression and paraventricular thalamus

Takeda highlights safety, efficacy of vedolizumab for UC and CD at ACG Annual Scientific Meeting

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

Sprout announces U.S. availability of Addyi for HSDD treatment in premenopausal women

BDSI announces FDA approval of BUNAVAIL sNDA for manufacturing specification change

New $6.7 million project aims to help kidney dialysis patients live longer

DePuy Synthes Spine launches new all-in-one pedicle screw system to help simplify spinal surgery

FDA approves Opdivo to treat patients with advanced non-small cell lung cancer

FDA approves Lonsurf drug for patients with advanced form of colorectal cancer

New partnership to deliver world-class healthcare through collaborative scientific research

Volunteer nurse back in isolation with Ebola complications

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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