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New microbial genes responsible for bile acid conversion is a major step forward for gut health

As the owner of a human body, you're carrying trillions of microbes with you everywhere you go. These microscopic organisms aren't just hitching a ride; many of them perform essential chemical reactions that regulate everything from our digestion to our immune system to our moods.

27 May 2021

Melatonin prevents kidney damage caused by metabolic complications of obesity

Scientists from the University of Granada (UGR), the Hospital Universitario La Paz (Madrid), and the University of Texas (USA) have taken an important step in the fight against kidney damage and its progression towards kidney failure, which is closely related to diabesity (obesity and its type 2 diabetes) and its complications.

27 May 2021

Blood sample analysis can help determine the origin of drugs

The opioid fentanyl is not only used in medical practice as a painkiller, but is also a popular recreational drug. In the United States in particular, fentanyl plays an important role in the opioid crisis that claims many victims every day.

27 May 2021

Study shows how rare but serious post-COVID-19 complication develops in children, adolescents

A multidisciplinary team from MassGeneral Hospital for Children (MGHfC), Brigham and Women's Hospital and other institutions have identified the mechanism of how an extremely rare but serious post-COVID-19 complication develops in children and adolescents.

26 May 2021

Scientists propose new strategies to find drugs that neutralize critical enzymes

Scientists from the University of Bath explore racemases and propose strategies for finding drugs that target these important enzymes.

26 May 2021

Discovery of novel SARS-related coronaviruses in bats

In a recent study published on the bioRxiv* server, Peng Zhou, Zheng-Li Shi and colleagues at the Wuhan Institute of Virology, with collaboration from scientists at the University of Chinese Academy of Sciences in China, have identified a new lineage of SARS-related coronaviruses that utilize bat angiotensin-converting enzyme 2 (ACE2) receptors for cell entry, which is the same receptor used by SARS-CoV-2 to infect host cells.

25 May 2021

The potential therapeutic value of CDK6 inhibitors in critical COVID-19

While drug repurposing has been explored in the context of the current coronavirus disease 2019 (COVID-19) pandemic, the success of this strategy has been limited so far. A new study, released as a preprint on the medRxiv* server, describes a new method of identifying a promising hit among drugs already in use.

24 May 2021

Little evidence for mRNA COVID-19 vaccine-associated thrombocytopenia, suggests new FDA study

Even as a host of vaccines have been rolled out to counter the coronavirus disease 2019 (COVID-19) pandemic, some serious adverse effects have been reported, in the form of thrombocytopenia. A new study in the journal Vaccine reports the results of an evaluation of reported cases of this condition, using data from the Vaccine Adverse Event Reporting System (VAERS).

24 May 2021

Researchers investigate link between the liver’s immune system composition and NASH pathology

Our livers work hard to perform an entire range of activities: helping us digest food, maintaining body temperature and serving as an important checkpoint of the immune system for everything that we eat.

24 May 2021

Which biomarkers can help predict adverse outcomes in COVID-19?

A team of researchers has conducted a systematic review to identify laboratory factors that can predict the risk of severe and critical COVID-19 as well as associated mortality rates. The team – from institutions in India and the USA – recently published their findings in the Journal of Clinical Medicine Research.

24 May 2021

Researchers uncover differences in itch mechanisms

Chronic skin itching drives more people to the dermatologist than any other condition. In fact, the latest science literature finds that 7% of U.S. adults, and between 10 and 20% of people in developed countries, suffer from dermatitis, a common skin inflammatory condition that causes itching.

21 May 2021

Risk factors for rare COVID-19 complications in children (MIS-C)

While the earlier waves of COVID-19 relatively spared children, some of the affected children have developed a systemic inflammatory condition, with occasionally fatal outcomes. Called multisystem inflammatory syndrome in children (MIS-C), its pathogenesis and risk factors are the subject of a new study on the medRxiv* preprint server.

21 May 2021

Researchers evaluate risk of developing new clinical conditions after acute phase of COVID-19 infection

One in 7 (14%) adults with coronavirus infection developed at least one new condition that required medical care during the post-acute phase of illness, which is 5% higher than adults with no coronavirus infection in 2020, finds a US study published by The BMJ today.

21 May 2021

Study analyzes the risk of other medical conditions after recovery from COVID-19

Owlstone Medical Launches Breath Testing for Digestive Health in Collaboration with Functional Gut Diagnostics and Functional Gut Clinic

Owlstone Medical today announced agreements with Functional Gut Clinic ("FGC") and Functional Gut Diagnostics (“FGD”).

From Owlstone Medical Ltd 18 May 2021

Liver News and Research

New microbial genes responsible for bile acid conversion is a major step forward for gut health

Melatonin prevents kidney damage caused by metabolic complications of obesity

Blood sample analysis can help determine the origin of drugs

Study shows how rare but serious post-COVID-19 complication develops in children, adolescents

Scientists propose new strategies to find drugs that neutralize critical enzymes

Discovery of novel SARS-related coronaviruses in bats

The potential therapeutic value of CDK6 inhibitors in critical COVID-19

Little evidence for mRNA COVID-19 vaccine-associated thrombocytopenia, suggests new FDA study

Researchers investigate link between the liver’s immune system composition and NASH pathology

Which biomarkers can help predict adverse outcomes in COVID-19?

Researchers uncover differences in itch mechanisms

Risk factors for rare COVID-19 complications in children (MIS-C)

Researchers evaluate risk of developing new clinical conditions after acute phase of COVID-19 infection

Study analyzes the risk of other medical conditions after recovery from COVID-19

Medicaid-Medicare partnership could cover lifesaving medications for hepatitis C

Blocking ABCB10 protein in liver cells protects against high blood sugar, fatty liver disease

Researchers use base editing to sustainably lower high LDL cholesterol levels

Combination approach can improve the success rate of cancer treatment

Researchers link “genetic signatures” of bacteria in the human gut to multiple diseases

Owlstone Medical Launches Breath Testing for Digestive Health in Collaboration with Functional Gut Diagnostics and Functional Gut Clinic

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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