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Brainlab launches ExacTrac Infrared Monitoring device for patient positioning during radiation therapy

Brainlab announced the availability of ExacTrac® Infrared Monitoring, an add-on device to existing treatment machines for monitoring patient positioning during radiation therapy treatments, at the American Association of Physicists in Medicine (AAPM) Annual Meeting last week.

26 Jul 2010

Calibra Medical's Finesse insulin patch-pen receives FDA clearance for use with Novo Nordisk's Novolog

Calibra Medical announced today it received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its Finesse™ insulin patch-pen for up to three-day use with Novo Nordisk's Novolog® rapid acting insulin. Combining the mealtime therapy-adherence benefits of insulin pumps with the simplicity and affordability of syringes and pens, Calibra's novel bolus-only patch-pen is a small, adhesively attached, flat device that can be operated discretely through clothing to deliver mealtime, snack time, and correction bolus insulin in seconds.

26 Jul 2010

Onyx reports positive results from carfilzomib Phase 2b 003-A1 study in multiple myeloma

Onyx Pharmaceuticals, Inc. today announced positive top-line results from the Phase 2b 003-A1 study of single-agent carfilzomib, a selective, next generation proteasome inhibitor, in patients with relapsed and refractory multiple myeloma.

26 Jul 2010

Research reveals molecular basis of neural circuits

The basal ganglia is a series of highly connected brain areas localised deep in the cerebral cortex that recently has attracted interest of neuroscientists when it was linked to learning, and discovered to be affected in a number of disorders of the addictive and obsessive spectrum, but also in Parkinson's disease (PD). And now researchers think they have understood why as they found that neurons in this area signal the beginning and the end of voluntary actions. In fact, problems in these neurons could explain the "incapacity to stop" seen in obsession or compulsive behaviour, but also the problems in learning and control of movement characteristic of Parkinson's

26 Jul 2010

Sec. of State Clinton signs 5-year AIDS control partnership agreement with Vietnam

During her trip to Vietnam, Secretary of State Hillary Rodham Clinton "engaged in health diplomacy by visiting the Ngoc Lam Pagoda orphanage for AIDS-affected children," Foreign Policy's blog "Madam Secretary" reports.

26 Jul 2010

ESC concerned over interpretation of JUPITER sub-analysis trial results about HDL cholesterol

The European Society of Cardiology (ESC) is concerned that interpretations of a paper about cholesterol, published in the Lancet, could act to deter ongoing research efforts into developing new therapeutic strategies to increase high density lipoprotein (HDL) cholesterol. Caution, the ESC experts advise, should be displayed in the interpretation of the results.

26 Jul 2010

Glioblastomas patients with affected stem cell niche experience progression-free survival

Patients with deadly glioblastomas who received high doses of radiation that hit a portion of the brain that harbors neural stem cells had double the progression-free survival time as patients who had lower doses or no radiation targeting the area, a study from the Radiation Oncology Department at UCLA's Jonsson Comprehensive Cancer Center has found.

26 Jul 2010

Cerenis, Novasep awarded French Government funding for development of CER-001 HDL mimetic

Cerenis Therapeutics SA (Cerenis), a biopharmaceutical company developing novel high-density lipoprotein (HDL) therapies to treat cardiovascular and other metabolic diseases, and Groupe Novasep (Novasep), a leading supplier of manufacturing solutions to the life sciences industries, announce today that they have received French Government funding through OSEO to finance the development of CER-001, a Cerenis HDL mimetic.

26 Jul 2010

Boehringer Ingelheim announces European CHMP Positive Opinion for TWYNSTA

Boehringer Ingelheim announced today that the European Committee for Medicinal Products for Human Use (CHMP) adopted a Positive Opinion for the approval of TWYNSTA®. It will be indicated in adults whose blood pressure is not adequately controlled on amlodipine and is also indicated as replacement therapy in adult patients receiving telmisartan and amlodipine from separate tablets can instead receive tablets of TWYNSTA containing the same component doses.

26 Jul 2010

Cerenis Therapeutics closes first round of series C, raises €40 million

Cerenis Therapeutics SA (Cerenis), a biopharmaceutical company specializing in the research and development of novel therapies based on the metabolism of HDL (the "good" cholesterol) to treat cardiovascular and other metabolic diseases, announced today it has raised €40 million in the first close of its series C financing. In this round €20 million came from the Fund for Strategic Investment (FSI) with an additional €20 million coming from the existing investors: Sofinnova Partners, HealthCap, Alta Partners and TVM Capital, EDF Ventures, OrbiMed and DAIWA Corporate Investment.

26 Jul 2010

North Shore-LIJ Health System seeks oropharynx patients for phase I clinical trial

The North Shore-LIJ Health System Department of Radiation Medicine announced today it is seeking patients with cancer of the oropharynx (back of the mouth) to participate in a Phase I clinical trial.Subjects must be newly diagnosed and not have undergone any previous treatment. Further, their cancer must be unassociated with the human papilloma virus (HPV-negative), or, if it is HPV-positive, they must be current or former pack-a-day smokers for at least 10 years.

26 Jul 2010

Outcomes selected to administer MTM program for employees in the State of Iowa

Outcomes Pharmaceutical Health Care has been selected by the State of Iowa Department of Administrative Services to administer a Medication Therapy Management program for the state employee health plan.

26 Jul 2010

Scientists develop nanoprobe to detect blood vessel growth in tumors

Formation of new blood vessels, also known as angiogenesis, is crucial for sustained tumor growth and cancer metastasis. Recently, clinically available therapies to suppress the growth of these vessels have been available to improve patient survival in some cancer types. Accurate detection and quantification of blood vessel growth using nonsurgical methods would greatly complement current therapies and allow physicians to quickly assess treatment regimens and adjust them as necessary. In the work published in the August issue of Experimental Biology and Medicine, Kessinger and coworkers have incorporated nanotechnology, material science, and the clinical imaging modality MRI, to create a nanosized probe capable of noninvasively visualizing and quantifying the blood vessel growth in tumors in a preclinical model.

26 Jul 2010

Cancer institute offers new tumor monitoring system for radiation therapy patients

A new system that utilizes a precise a GPS-like system to track prostate cancer tumors is now being offered to patients undergoing radiation therapy at Cedars-Sinai's Samuel Oschin Comprehensive Cancer Institute. The monitoring system, called Calypso, allows radiation beams to more precisely target the cancer as it gives real-time positioning information that allows the radiation beams to focus directly on the cancer.

23 Jul 2010

Prevalence of HD substantially underestimated in the UK

The prevalence of Huntington's disease is substantially underestimated in the UK, with significant implications for those affected, the healthcare system, and research. New estimates of prevalence, and their implications, are discussed in a comment published in an upcoming Lancet, written by Professor Sir Michael Rawlins, who is the Chairman of the UK National Institute for Health and Clinical Excellence, but writes in his capacity as an Honorary Professor of the London School of Hygiene and Tropical Medicine, UK.

23 Jul 2010

ACLU says some nursing homes use 'scare tactics' to keep psychiatric patients

The American Civil Liberties Union says in court papers that some for-profit nursing home operators are using "scare tactics" to persuade psychiatric patients to stay in their facilities. "The action follows a historic court settlement in which Illinois authorities pledged to offer supportive community-based housing and treatment to roughly 4,500 psychiatric patients who now live in two dozen large nursing homes designated as Institutions for Mental Diseases.

23 Jul 2010

Securing universal access to HIV prevention, care, treatment and support

The biennial meeting of the global AIDS community concluded today with clear evidence of tangible progress in HIV research and programme scale up, yet facing an urgent need for increased resources, the protection of human rights, and broader use of scientifically sound prevention strategies. Delegates and organizers depart Vienna - where the conference opened 18 July under the theme of Rights Here, Right Now -- with a renewed commitment to push for securing universal access to HIV prevention, care, treatment and support.

23 Jul 2010

Today's OpEds: Varying points on the nation's doctor shortage, benefits of negative studies, and what about universal health care?

In the long list of problems affecting the American health care system, the shortage of general practitioners and overabundance of specialists is usually ranked near the top. There is truth to this: only 32 percent of physicians practice primary care medicine. As a result, patients have to wait longer to see their doctors and are more likely to be seen by nurse practitioners and physician assistants instead. However, pediatrics has the opposite problem: a growing shortage of pediatric subspecialists (Dennis Rosen, 7/22).

23 Jul 2010

Vienna Declaration signed to support evidence-based drug policy for improving community health

Sandra Roelofs, First Lady of Georgia; George Tsereteli, Georgia's Deputy Chairman of Parliament; and Irakli Giorgobiani, Georgia's Vice Minister of Labour, Health and Social Affairs, today signed the Vienna Declaration, the official declaration of the XVIII International AIDS conference in Vienna, Austria.

23 Jul 2010

NxStage Medical second-quarter net revenue increases 21% to $44.0 million

NxStage Medical, Inc., a leading manufacturer of innovative dialysis products, today reported record financial results for the second quarter of 2010 ended June 30, 2010, with total revenue above the top end of its guidance range.

23 Jul 2010

Therapy News and Research

Brainlab launches ExacTrac Infrared Monitoring device for patient positioning during radiation therapy

Calibra Medical's Finesse insulin patch-pen receives FDA clearance for use with Novo Nordisk's Novolog

Onyx reports positive results from carfilzomib Phase 2b 003-A1 study in multiple myeloma

Research reveals molecular basis of neural circuits

Sec. of State Clinton signs 5-year AIDS control partnership agreement with Vietnam

ESC concerned over interpretation of JUPITER sub-analysis trial results about HDL cholesterol

Glioblastomas patients with affected stem cell niche experience progression-free survival

Cerenis, Novasep awarded French Government funding for development of CER-001 HDL mimetic

Boehringer Ingelheim announces European CHMP Positive Opinion for TWYNSTA

Cerenis Therapeutics closes first round of series C, raises €40 million

North Shore-LIJ Health System seeks oropharynx patients for phase I clinical trial

Outcomes selected to administer MTM program for employees in the State of Iowa

Scientists develop nanoprobe to detect blood vessel growth in tumors

Cancer institute offers new tumor monitoring system for radiation therapy patients

Prevalence of HD substantially underestimated in the UK

ACLU says some nursing homes use 'scare tactics' to keep psychiatric patients

Securing universal access to HIV prevention, care, treatment and support

Today's OpEds: Varying points on the nation's doctor shortage, benefits of negative studies, and what about universal health care?

Vienna Declaration signed to support evidence-based drug policy for improving community health

NxStage Medical second-quarter net revenue increases 21% to $44.0 million

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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