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Agenus reports net loss attributable to common stockholders of $5.8 million for Q4 2013

Agenus Inc., a biopharmaceutical company developing a portfolio of immuno-oncology candidates, including checkpoint modulators (CPMs), heat shock protein vaccines and adjuvants, today announced its financial results and business highlights for the fourth quarter and year ended December 31, 2013.

5 Mar 2014

Kamada initiates Phase 2/3 clinical trial of Glassia to treat pediatric patients with T1D

Kamada Ltd. (NASDAQ:KMDA) (TASE:KMDA), a plasma-derived protein therapeutics company focused on orphan indications, announces the initiation of a Phase 2/3 clinical trial of Glassia®, the Company's proprietary human Alpha-1 Antitrypsin (AAT), to treat newly diagnosed pediatric patients with type 1 diabetes (T1D).

5 Mar 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods.

5 Mar 2014

New study shows male hormones play important role; may enhance IVF therapy in women

Several fertility clinics across the country are beginning to administer testosterone, either through a patch or a gel on the skin, to increase the number of eggs produced by certain women undergoing in vitro fertilization (IVF).

5 Mar 2014

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

For the first time, scientists have demonstrated the effectiveness of a small-molecule drug in protecting nonhuman primates from the lethal Marburg virus. Their work, published online in the journal Nature, is the result of a continuing collaboration between Army scientists and industry partners that also shows promise for treating a broad range of other viral diseases.

5 Mar 2014

New PhoneSoap Charger is most effective way to kill bacteria growing on cell phones

Cell phones have become our constant companions, and as a result, they are exposed to many bacteria and viruses. When we open a door, shake hands, use an ATM or dozens of other daily tasks, our hands come in contact with germs, and numerous studies have shown that a significant number of bacteria, such as the flu virus, staph, strep, E. coli, and salmonella, are transferred from our hands to our cell phones every time we pick them up.

5 Mar 2014

Plymouth University enters partnership with Brain Tumour Research

Patients, carers, scientists, clinicians and charities from across the UK are heading to Westminster today for the launch of a ground-breaking new collaborative partnership between the charity Brain Tumour Research and Plymouth University Peninsula Schools of Medicine and Dentistry. The announcement will open a new chapter in long-term sustainable and continuous research into the biggest cancer killer of children and adults under 40.

5 Mar 2014

Researchers develop adjuvant which enhances effect of virus transduction

Lentiviruses, which belong to the family of retroviruses, are used as vectors to exchange genetic material in cells and can be used to replace a defective gene as defined by gene therapy.

5 Mar 2014

Set of genes appear to predict which tumors can evade detection by immune system

Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body's immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.

5 Mar 2014

Cell-cycle arrest biomarkers validated for acute kidney injury

Saeed A. Jortani, Ph.D., associate clinical professor in the University of Louisville's Department of Pathology and Laboratory Medicine, headed up one of three labs in the United States involved in determining two new markers for acute kidney injury (AKI). The research group's paper, "Validation of Cell-Cycle Arrest Biomarkers for Acute Kidney Injury Using Clinical Adjudication," was posted online Feb. 25 by the American Journal of Respiratory and Critical Care Medicine.

5 Mar 2014

Low-amplitude electric fields help hard-to-heal chronic wounds

Naturally occurring electricity in our cells is key to how our bodies function, and that includes the healing of wounds.

5 Mar 2014

Berkeley Lab scientists explore bacteria-resistant materials as a line of defense against Staph infection

The bacterium Staphylococcus aureus (S. aureus) is a common source of infections that occur after surgeries involving prosthetic joints and artificial heart valves. The grape-shaped microorganism adheres to medical equipment, and if it gets inside the body, it can cause a serious and even life-threatening illness called a Staph infection. The recent discovery of drug-resistant strains of S. aureus makes matters even worse.

5 Mar 2014

Researchers unravel function of proteins involved in cell metabolism

UCPs or uncoupling proteins are present in mitochondria, the powerhouse of each cell in the body. The functions of most of the five known UCPs remain mysterious (UCP2-UCP5), whereby only the distinct function for UCP1 has thus far been discovered.

5 Mar 2014

Researchers identify genes that appear to predict tumors that can evade detection by immune system

Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body’s immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.

5 Mar 2014

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

A combination of iron-oxide nanoparticles and an alternating magnetic field, which together generate heat, have activated an immune system response to tumors in mice according to an accepted manuscript by Dartmouth-Hitchcock Norris Cotton Center researchers in the journal Nanomedicine: Nanotechnology, Biology and Medicine released online on February 24, 2014.

5 Mar 2014

Georgia Regents Medical Center explores new treatment for Parkinson's disease-related constipation

Georgia Regents Medical Center is among about a dozen centers nationally exploring the potential of a new drug that may offer relief to people with Parkinson's who have failed standard approaches to treating constipation.

5 Mar 2014

New probes help to quantify normally folded and misfolded conformations of protein in cells

Scientists at The Scripps Research Institute (TSRI) have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest in cells under different conditions.

5 Mar 2014

Researchers find antibody that may be used in future treatments for recurrent small-cell lung cancer

Researchers at Norris Cotton Cancer Center have found an antibody that may be used in future treatments for recurrent small-cell lung cancer, which currently has no effective therapy.

5 Mar 2014

Study: Thickness of brain's cortex linked with person's change in IQ

Rate of change in the thickness of the brain's cortex is an important factor associated with a person's change in IQ, according to a collaborative study by scientists in five countries including researchers at the Montreal Neurological Institute and Hospital - The Neuro, at McGill University and the McGill University Health Centre.

5 Mar 2014

Nerve cells from horse stem cells may pave way for cell therapies, say researchers

Horses suffering from neurological conditions similar to those that affect humans could be helped by a breakthrough from stem cell scientists.

5 Mar 2014

B Cell News and Research

Agenus reports net loss attributable to common stockholders of $5.8 million for Q4 2013

Kamada initiates Phase 2/3 clinical trial of Glassia to treat pediatric patients with T1D

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

New study shows male hormones play important role; may enhance IVF therapy in women

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

New PhoneSoap Charger is most effective way to kill bacteria growing on cell phones

Plymouth University enters partnership with Brain Tumour Research

Researchers develop adjuvant which enhances effect of virus transduction

Set of genes appear to predict which tumors can evade detection by immune system

Cell-cycle arrest biomarkers validated for acute kidney injury

Low-amplitude electric fields help hard-to-heal chronic wounds

Berkeley Lab scientists explore bacteria-resistant materials as a line of defense against Staph infection

Researchers unravel function of proteins involved in cell metabolism

Researchers identify genes that appear to predict tumors that can evade detection by immune system

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

Georgia Regents Medical Center explores new treatment for Parkinson's disease-related constipation

New probes help to quantify normally folded and misfolded conformations of protein in cells

Researchers find antibody that may be used in future treatments for recurrent small-cell lung cancer

Study: Thickness of brain's cortex linked with person's change in IQ

Nerve cells from horse stem cells may pave way for cell therapies, say researchers

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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