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Cell Therapeutics initiates Phase 3 clinical trial to evaluate pacritinib in patients with myelofibrosis

Cell Therapeutics, Inc. (CTI) (NASDAQ and MTA: CTIC) today announced the initiation of a Phase 3 clinical trial, known as PERSIST-2, which will evaluate pacritinib, a novel, investigational JAK2/FLT3 inhibitor, in patients with myelofibrosis whose platelet counts are less than or equal to 100,000 per microliter (uL).

3 Mar 2014

Study establishes innovative approaches to improve vision of young children with brain tumor

Robert Avery, DO, MSCE, of Children's National Health System and colleagues are establishing innovative approaches with technology and medication to improve the vision of young children who have visual pathway glioma, a type of brain tumor.

3 Mar 2014

Scientists unveil role of microRNAs in regulating neuroblastoma, pointing to new therapeutic possibilities

Neuroblastoma is one of the most common and lethal types of childhood cancers. In a paper published online today in OncoTarget, a researcher at the University of Texas Health Science Center at San Antonio unveils the important role of microRNAs in regulating neuroblastoma development, pointing to new therapeutic possibilities.

3 Mar 2014

Max Planck scientists identify new mechanisms in cellular stress response

When an organism is exposed to life-threatening conditions, it sounds the alarm and a cellular emergency program, the heat shock response, is initiated.

3 Mar 2014

Researcher to receive AACR- Joseph H. Burchenal Memorial Award for achievement in cancer research

John F. DiPersio, M.D., Ph.D., will be recognized with the 19th Annual American Association for Cancer Research-Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research at the AACR Annual Meeting 2014, to be held in San Diego, Calif., April 5-9.

3 Mar 2014

Bayer HealthCare joins NORD to promote awareness of Rare Disease Day

Bayer HealthCare is joining the National Organization for Rare Disorders (NORD) and others in raising awareness of Rare Disease Day, which is being celebrated today around the world.

3 Mar 2014

New methodology for rapid detection of antibiotics in blood paves way to drug development, personalized treatment

A new methodology for rapidly measuring the level of antibiotic drug molecules in human blood serum has been developed, paving the way to applications within drug development and personalised medicine.

3 Mar 2014

Researchers discover novel treatments for psoriasis that are likely to cause fewer side effects

Almost ten years ago, the group led by Erwin Wagner, currently at the Spanish National Cancer Research Centre (CNIO), developed genetically modified mice showing symptoms very reminiscent to psoriasis.

28 Feb 2014

Penn research team discovers new cost-effective way to fight rare blood disorder

A University of Pennsylvania research team has defined a possible new way to fight a disease that is currently treatable only with the most expensive drug available for sale in the United States.

28 Feb 2014

UCLA develops experimental treatment that eliminates acute type of leukemia in mice

A diverse team of scientists from UCLA's Jonsson Comprehensive Cancer Center has developed an experimental treatment that eradicates an acute type of leukemia in mice without any detectable toxic side effects.

28 Feb 2014

Protein interaction network provides invaluable resource to identify targets for Huntington's disease

Researchers at the Buck Institute have identified and categorized thousands of protein interactions involving huntingtin, the protein responsible for Huntington's disease (HD). To use an analogy of a human social network, the identified proteins are like "friends" and "friends of friends" of the HD protein.

28 Feb 2014

Scientists carry out first studies of living biological cells using high-energy X-rays

G-ttingen-based scientists working at DESY's PETRA III research light source have carried out the first studies of living biological cells using high-energy X-rays. The new method shows clear differences in the internal cellular structure between living and dead, chemically fixed cells that are often analysed.

28 Feb 2014

Protein that controls Drosophila nervous system may play role in reversing brain injuries in human

A protein that controls the metamorphosis of the common fruit fly could someday play a role in reversing brain injuries, said Duke University researchers.

28 Feb 2014

Researchers find new technique to detect just a handful of lurking tumor cells

Beating cancer is all about early detection, and new research from the University of South Carolina is another step forward in catching the disease early. A team of chemists is reporting a new way to detect just a handful of lurking tumor cells, which can be outnumbered a billion to one in the bloodstream by healthy cells.

28 Feb 2014

Study looks at fighting 'epidemic' of dangerous behavior

While drivers tend to believe it is dangerous to text and drive, many say they can still do it safely. Now Washington State University researchers say drivers can be discouraged from the practice with public service announcements that evoke their fear of death in graphic terms.

28 Feb 2014

TSRI scientists describe severe immune overreaction caused by flu infections

Scientists at The Scripps Research Institute have mapped key elements of a severe immune overreaction—a “cytokine storm”—that can both sicken and kill patients who are infected with certain strains of flu virus.

28 Feb 2014

Research reveals very unique evolutionary innovations in primate brain

New research by UC Santa Barbara's Kenneth S. Kosik, Harriman Professor of Neuroscience, reveals some very unique evolutionary innovations in the primate brain.

28 Feb 2014

Researchers analyze impact of chocolate consumption in vascular health

It might seem too good to be true, but dark chocolate is good for you and scientists now know why. Dark chocolate helps restore flexibility to arteries while also preventing white blood cells from sticking to the walls of blood vessels.

28 Feb 2014

Silver nanoparticles in dietary supplements, cosmetics and food packaging can cause damage to cells

Endocrine disrupters are not the only worrying chemicals that ordinary consumers are exposed to in everyday life. Also nanoparticles of silver, found in e.g. dietary supplements, cosmetics and food packaging, now worry scientists.

28 Feb 2014

Vaccine targeting tumors could initiate immune response to fight cancer

Cincinnati Cancer Center (CCC) and UC Cancer Institute researchers have found that a vaccine, targeting tumors that produce a certain protein and receptor responsible for communication between cells and the body's immune system, could initiate the immune response to fight cancer.

28 Feb 2014

B Cell News and Research

Cell Therapeutics initiates Phase 3 clinical trial to evaluate pacritinib in patients with myelofibrosis

Study establishes innovative approaches to improve vision of young children with brain tumor

Scientists unveil role of microRNAs in regulating neuroblastoma, pointing to new therapeutic possibilities

Max Planck scientists identify new mechanisms in cellular stress response

Researcher to receive AACR- Joseph H. Burchenal Memorial Award for achievement in cancer research

Bayer HealthCare joins NORD to promote awareness of Rare Disease Day

New methodology for rapid detection of antibiotics in blood paves way to drug development, personalized treatment

Researchers discover novel treatments for psoriasis that are likely to cause fewer side effects

Penn research team discovers new cost-effective way to fight rare blood disorder

UCLA develops experimental treatment that eliminates acute type of leukemia in mice

Protein interaction network provides invaluable resource to identify targets for Huntington's disease

Scientists carry out first studies of living biological cells using high-energy X-rays

Protein that controls Drosophila nervous system may play role in reversing brain injuries in human

Researchers find new technique to detect just a handful of lurking tumor cells

Study looks at fighting 'epidemic' of dangerous behavior

TSRI scientists describe severe immune overreaction caused by flu infections

Research reveals very unique evolutionary innovations in primate brain

Researchers analyze impact of chocolate consumption in vascular health

Silver nanoparticles in dietary supplements, cosmetics and food packaging can cause damage to cells

Vaccine targeting tumors could initiate immune response to fight cancer

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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