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Study reveals early role of SYNGAP1 gene in brain development

The gene SYNGAP1, the variants of which are top risk factors for Autism Spectrum Disorder (ASD), has previously unappreciated effects on the developing brain, according to a new study published in Nature Neuroscience.

9 Nov 2023

ICMRA celebrates 10 years of global cooperation in regulating medicinal products

This year marks ten years since the MHRA joined seven other global regulators to establish ICMRA to address the need for strong global cooperation and alignment in the regulation of medicinal products.

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Study finds 4% of Icelanders to carry an actionable genotype associated with shortened lifespan

Scientists at deCODE genetics, a subsidiary of Amgen, have published a study on actionable genotypes detected in the Icelandic population and their association with lifespan.

8 Nov 2023

Genetic variants likely affect sleep quality and quantity in children, study finds

Previous research has identified genetic variants associated with insomnia and sleep duration in adults. Now a study published in the Journal of Child Psychology and Psychiatry has found that these variants also likely affect sleep quality and quantity in children.

8 Nov 2023

Gene expression in nearby healthy tissue may be a better predictor of lung cancer recurrence

Genetic information collected from seemingly healthy tissue near lung tumors may be a better predictor of whether cancer will come back after treatment than analysis of the tumors themselves, according to new research led by NYU Langone Health and its Perlmutter Cancer Center.

8 Nov 2023

Simultaneous inhibition of two proteins may be a new strategy for tackling triple-negative breast cancer

Researchers at the Centre for Genomic Regulation and Vall d'Hebron Institute of Oncology have shown that the simultaneous inhibition of two different proteins may represent a new strategy for tackling triple-negative breast cancer, the most aggressive and drug-resistant form of breast cancer.

8 Nov 2023

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Concurrent sequencing of DNA and RNA to detect the predisposition to hereditary cancer.

8 Nov 2023

Pharmacogenomics holds promise for personalized dementia therapies

Pharmacogenomics-based studies in the research for personalized therapeutics for dementia

8 Nov 2023

How glucose restriction makes lung cancer cells more aggressive

One of the hallmarks of cancer cell development is its dependence on sugar, especially glucose, to grow and divide.

7 Nov 2023

Targeting MYC-SPT5 interaction could lead to novel cancer therapies

MYC family genes are essential for the human organism. According to current knowledge, they regulate the expression of most cellular genes.

7 Nov 2023

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

To what extent can genetic variations explain the associations between screen time and psychiatric problems in children?

Researchers investigated the role of genetics in the phenotypic association between screen time and psychiatric problems using a large population-based cohort study of preadolescents.

7 Nov 2023

The association between neighborhood deprivation, DNA methylation, and gene expression in breast tissue for Black and White women with breast cancer

Researchers investigated the association between neighborhood deprivation and alterations in DNA methylation and gene expression in breast cancer tissues of Black and White women.

7 Nov 2023

Stellaromics secures $25 million in series a funding to advance 3D spatial multi-omic profiling

Stellaromics today announced that the company has raised $25 million in a Series A financing round.

7 Nov 2023

Enhanc3D Genomics expands leadership team with the appointment of Hazel Jones as Chief Operating Officer

Enhanc3D Genomics today announced the appointment of Hazel Jones as Chief Operating Officer.

6 Nov 2023

New study unveils Foxp3's role in regulatory T cell chromatin architecture

Regulatory T cells are specialized immune cells that suppress the immune response and prevent the body from attacking its own cells.

6 Nov 2023

TIMP2 protein identified as key player in brain plasticity and memory

Researchers explored the molecular and cellular processes regulated by tissue inhibitor of metalloproteinases-2 (TIMP2) in the extracellular matrix (ECM) of the adult brain hippocampus.

6 Nov 2023

Cutting-edge 'precision medicine' shows great potential to improve diabetes care

Cutting-edge “precision medicine” has great potential to advance the diagnosis, treatment and ultimate prevention of different forms of diabetes, an international coalition of scientists reports in a sweeping assessment of the state of the field around the world.

6 Nov 2023

Genes News and Research

Study reveals early role of SYNGAP1 gene in brain development

ICMRA celebrates 10 years of global cooperation in regulating medicinal products

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Cannabis use alters DNA methylation, with implications beyond smoking effects

Study finds 4% of Icelanders to carry an actionable genotype associated with shortened lifespan

Genetic variants likely affect sleep quality and quantity in children, study finds

Gene expression in nearby healthy tissue may be a better predictor of lung cancer recurrence

Simultaneous inhibition of two proteins may be a new strategy for tackling triple-negative breast cancer

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Pharmacogenomics holds promise for personalized dementia therapies

How glucose restriction makes lung cancer cells more aggressive

Targeting MYC-SPT5 interaction could lead to novel cancer therapies

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

To what extent can genetic variations explain the associations between screen time and psychiatric problems in children?

The association between neighborhood deprivation, DNA methylation, and gene expression in breast tissue for Black and White women with breast cancer

Stellaromics secures $25 million in series a funding to advance 3D spatial multi-omic profiling

Enhanc3D Genomics expands leadership team with the appointment of Hazel Jones as Chief Operating Officer

New study unveils Foxp3's role in regulatory T cell chromatin architecture

TIMP2 protein identified as key player in brain plasticity and memory

Cutting-edge 'precision medicine' shows great potential to improve diabetes care

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