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Novel monoclonal antibody therapy shows promising results in patients with moderate to severe atopic dermatitis

Patients with moderate to severe atopic dermatitis who participated in a clinical trial of rocatinlimab - a novel, patient-tailored monoclonal antibody therapy - showed promising results both while taking the drug and up to 20 weeks after the therapy was stopped, Mount Sinai researchers reported in The Lancet.

12 Dec 2022

Aging influences the diagnosis and treatment of heart attacks in patients over age 75

For people ages 75 and older, age-related changes in general health and in the heart and blood vessels require consideration and likely modifications in how heart attacks and heart disease are treated, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

12 Dec 2022

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

12 Dec 2022

Researchers discover a previously unknown mechanism that drives aging

Northwestern University researchers have discovered a previously unknown mechanism that drives aging.

9 Dec 2022

Bariatric surgical procedures can lead to enduring improvements in urinary incontinence

Urinary incontinence is a common complaint among adults with severe obesity. The majority of adults with urinary incontinence who undergo Roux-en-Y gastric bypass or sleeve gastrectomy, the two most common types of weight loss surgery, can reasonably expect enduring improvements in urinary incontinence, according to a new study published today in JAMA Network Open.

9 Dec 2022

Study may allow patients with multiple breast lesions to consider breast-conserving therapy as treatment option

Patients with multiple tumors in the same breast who underwent a lumpectomy followed by radiation therapy had local recurrence rates comparable to those historically observed in patients with a single tumor, according to results from the ACOSOG Z11102 (Alliance) prospective phase II clinical trial, which were presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Patients with invasive breast cancer who had low scores on an investigational gene molecular signature had similar rates of local recurrence whether or not they received adjuvant radiation therapy after breast-conserving surgery, according to results of a meta-analysis presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

Study finds disparities in breast cancer screening, treatment access for underserved communities

Barriers to breast cancer screening remain despite Medicaid expansion for preventive screening tests and implementation of patient navigation programs under the Affordable Care Act, with women from underserved communities experiencing disproportionately low rates of screening mammography, according to a study that was conducted by New York Medical College (NYMC) School of Medicine (SOM) faculty and students and recently published in BMC Women’s Health.

9 Dec 2022

Georgia State brain researcher receives NIH grant to create a model for personalized cancer treatments

A brain researcher at Georgia State University has been awarded a five-year, $3.06 million grant from the National Cancer Institute at the National Institutes of Health to create a model for personalized cancer treatments.

8 Dec 2022

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma – a lethal form of salivary gland cancer that currently has no treatment options.

8 Dec 2022

VirtaMed and CICE to announce partnership for gynecological endoscopy certification

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From VirtaMed 8 Dec 2022

Low-intensity ultrasound therapies may help rebuild stronger knees

Low-intensity ultrasound therapies may one day rebuild stronger knees following injury or surgery, thanks to research by Dr. Anu Subramanian at The University of Alabama in Huntsville (UAH) that's being supported by the National Institutes of Health.

7 Dec 2022

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent in combination with anastrozole, according to results from the phase II TRIO-US B-12 TALENT trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immune response inside the nose that fights off viruses responsible for upper respiratory infections.

7 Dec 2022

New ASTRO guideline provides recommendations on the use of radiation therapy for endometrial cancer

A newly updated clinical guideline from the American Society for Radiation Oncology provides recommendations on the use of radiation therapy and systemic therapy after surgery to treat patients with endometrial cancer.

7 Dec 2022

COVID-19 disruptions associated with lowest number of Australia’s public hospital elective surgeries

The number of patients treated in the 2021–22 financial year from Australia’s public hospital elective surgery waiting lists (‘elective’ meaning non-emergency) fell to the lowest level since 2010–11. This was associated with disruptions to hospital services as a result of COVID-19.

7 Dec 2022

Surgery News and Research

Novel monoclonal antibody therapy shows promising results in patients with moderate to severe atopic dermatitis

Aging influences the diagnosis and treatment of heart attacks in patients over age 75

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

Researchers discover a previously unknown mechanism that drives aging

Bariatric surgical procedures can lead to enduring improvements in urinary incontinence

Study may allow patients with multiple breast lesions to consider breast-conserving therapy as treatment option

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Study finds disparities in breast cancer screening, treatment access for underserved communities

Georgia State brain researcher receives NIH grant to create a model for personalized cancer treatments

Therapeutic activation of p53 could offer new treatment option for salivary gland cancer

VirtaMed and CICE to announce partnership for gynecological endoscopy certification

Low-intensity ultrasound therapies may help rebuild stronger knees

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

New ASTRO guideline provides recommendations on the use of radiation therapy for endometrial cancer

COVID-19 disruptions associated with lowest number of Australia’s public hospital elective surgeries

Mount Sinai first in New York to offer telehealth services for low-acuity patients who call 911

Leapfrog names USC Norris Cancer Hospital a 2022 Top Teaching Hospital

Study examines whether cortisone-like medicine can reduce pain after total knee arthroplasty

UHN’s Ajmera Transplant Centre performed a groundbreaking parathyroid transplant

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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