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Researchers develop new technology that reveals secrets of cellular memory

Cells in our body are constantly dividing to maintain our body functions. At each division, our DNA code and a whole machinery of supporting components has to be faithfully duplicated to maintain the cell's memory of its own identity.

25 Feb 2014

European Commission invests nearly $475 million in gene transfer and gene therapy projects

Over the past three funding stages, the European Commission has invested nearly $475 million in 100 projects in the gene transfer and gene therapy field.

25 Feb 2014

Study: Blacks are more likely to have precursor condition than whites

Blacks may be twice as likely as whites to develop multiple myeloma because they are more likely to have a precursor condition known as monoclonal gammopathy of undetermined significance (MGUS), a Mayo Clinic study has found.

25 Feb 2014

Novel two-pronged strategy targeting DNA synthesis treats leukemia in mice

A novel two-pronged strategy targeting DNA synthesis can treat leukemia in mice, according to a study in The Journal of Experimental Medicine.

25 Feb 2014

Tel Aviv University scientists target drug-resistant ovarian tumors with nanotechnology

Ovarian cancer accounts for more deaths of American women than any other cancer of the female reproductive system. According to the American Cancer Society, one in 72 American women will be diagnosed with ovarian cancer, and one in 100 will ultimately die of the condition.

24 Feb 2014

Study highlights novel reprogramming method that offers new hope for treating liver failure

The power of regenerative medicine now allows scientists to transform skin cells into cells that closely resemble heart cells, pancreas cells and even neurons. However, a method to generate cells that are fully mature-a crucial prerequisite for life-saving therapies-has proven far more difficult.

24 Feb 2014

New system delivers anti-inflammatory drugs to immune cells gone out of control

Researchers at the University of Illinois at Chicago have developed a system for precisely delivering anti-inflammatory drugs to immune cells gone out of control, while sparing their well-behaved counterparts. Their findings were published online Feb. 23 in Nature Nanotechnology.

24 Feb 2014

Researchers produce novel microparticles

A team of researchers of Karlsruhe Institute of Technology (KIT) and the University of Michigan/USA has produced novel microparticles, whose surface consists of three chemically different segments.

24 Feb 2014

Researchers identify novel strategies to develop more efficient vaccines against encapsulated bacteria

Researchers have discovered the presence of a novel subtype of innate lymphoid cells in human spleen essential for the production of antibodies. This discovery, published in the prestigious journal Nature Immunology, clears the path to the identification of novel strategies to develop more efficient vaccines against encapsulated bacteria, considered highly virulent.

24 Feb 2014

Scientists develop stem cell based method for restoring strength to damaged skeletal muscles in elderly

A study co-published in Nature Medicine this week by University of Toronto researcher Penney Gilbert has determined a stem cell based method for restoring strength to damaged skeletal muscles of the elderly.

24 Feb 2014

Scientists discover how viral DNA of HBV can be degraded in cell nucleus

Scientists from the Helmholtz Zentrum München and the Technische Universität München have discovered how the viral DNA of the hepatitis B virus (HBV) can be degraded in the cell nucleus of liver cells, consequently allowing the virus to be eliminated.

24 Feb 2014

Research explains how cells behave when placed in low oxygen environment

Research at the University of Liverpool has explained how cells behave when placed in a low oxygen environment, a development that could have implications for cancer patients and other serious illnesses.

24 Feb 2014

Researchers discover that immune cells control blood stem cells in bone marrow

Researchers in Bern have discovered that, during a viral infection, immune cells control the blood stem cells in the bone marrow and therefore also the body's own defences. The findings could allow for new forms of therapy, such as for bone marrow diseases like leukaemia.

24 Feb 2014

Cell therapy: A powerful treatment for cancer patients

Investigators from Memorial Sloan Kettering Cancer Center have reported more encouraging news about one of the most exciting methods of cancer treatment today. The largest clinical study ever conducted to date of patients with advanced leukemia found that 88 percent achieved complete remissions after being treated with genetically modified versions of their own immune cells.

24 Feb 2014

New innovative technique can carry chemotherapy safely and release inside cancer cells

Researchers from the cancer nanotechnology and signal transduction and therapeutics programs of UCLA's Jonsson Comprehensive Cancer Center (JCCC) have developed an innovative technique that can carry chemotherapy safely and release it inside cancer cells when triggered by two-photon laser in the infrared red wave length.

24 Feb 2014

Altering sunitinib dosing schedule improves tolerability

Shortening the time that patients with advanced renal cell carcinoma are on and off treatment with sunitinib improves the drug’s overall tolerability without affecting its efficacy, say Japanese researchers.

21 Feb 2014

Advanced age should not preclude sunitinib use for mRCC

Elderly kidney cancer patients benefit from sunitinib therapy just as much as their younger counterparts, a retrospective analysis of six clinical trials shows.

21 Feb 2014

Researchers develop new method to obtain three chemically different patches on same microparticle

Micromachines, nanorobots, multifunctional drug transporters, and matrices for tissue growth – these and many other applications would benefit from three-dimensional microstructures that present different (bio)chemical ligands that offer control over directionality. In the journal Angewandte Chemie, a team of German and American researchers has now reported the production of microparticles whose surface consists of three separate areas (“patches”) that can be decorated with three different (bio)molecules.

21 Feb 2014

Chewable drug candidate BTI320 can potentially prevent added sugar intake

It's official: sugar is not so sweet—for our health, that is. The new study "Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults," published in JAMA Internal Medicine, examines the intake of "added sugars," and the results suggest that sugar is now an independent risk factor for heart disease and other chronic diseases.

21 Feb 2014

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Patients with HPV-positive squamous cell carcinoma of the oropharynx (SCCOP) had a longer time to development of distant metastasis (DM) after initial treatment, and had more metastatic sites in more atypical locations compared to HPV-negative patients, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014