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Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Researchers have mapped the complex epigenetic and transcriptomic landscape of cancer, revealing key regulatory elements across 11 tumor types that could unlock new insights into cancer progression and metastasis.

5 Nov 2023

New atlas of fetal kidney reveals cell trajectories and disease signatures

Scientists have examined the gene expression patterns of single cells from 5 human fetal kidneys to create the most complete atlas of the fetal kidney to date.

3 Nov 2023

Tobacco smoking undermines anti-cancer safeguards by causing harmful DNA mutations

Scientists at the Ontario Institute for Cancer Research (OICR) have uncovered one way tobacco smoking causes cancer and makes it harder to treat by undermining the body's anti-cancer safeguards.

3 Nov 2023

Some beneficial effects of exercise may be driven by the immune system, study suggests

The connection between exercise and inflammation has captivated the imagination of researchers ever since an early 20th-century study showed a spike of white cells in the blood of Boston marathon runners following the race.

3 Nov 2023

Nutrition and aging: A two-way relationship

With so much hype in the media about miracle diets and nutritional supplements, one is invariably tempted to look for a single, food-based magic bullet that will increase the likelihood of living a longer, healthier life.

3 Nov 2023

High-impact clinical trial results to be presented at ASN Kidney Week 2023

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented in-person at ASN Kidney Week 2023 November 1–November 5.

3 Nov 2023

Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more.

2 Nov 2023

Study reveals how formaldehyde alters gene expression through epigenetics

Epigenetics, the chemical mechanisms that controls the activity of genes, allows our cells, tissues and organs to adapt to the changing circumstances of the environment around us.

2 Nov 2023

Gene discovery sheds light on ovary development

Researchers at the Francis Crick Institute and the Université Cote d'Azur, together with other labs in France and Switzerland, have identified a gene which is an early determining factor of ovary development in mice.

2 Nov 2023

Researchers discover new mechanism of cancer treatment resistance

A surprising mechanism that makes some cancers treatment-resistant has been discovered by Weill Cornell Medicine and NewYork-Presbyterian investigators.

2 Nov 2023

Scientists decode genetic programs controlling sex-specific organ development

The development of sex-specific characteristics is frequently seen in mammals. These characteristics stem from the activation of corresponding genetic programs that until now have been largely undescribed by the scientific community.

2 Nov 2023

Gut bacteria promote social behavior and wound healing through oxytocin signaling

The gut microbiome, a community of trillions of microbes living in the human intestines, has an increasing reputation for affecting not only gut health but also the health of organs distant from the gut.

2 Nov 2023

LHPP gene identified as a potential target for treatment-resistant depression

Major depressive disorder (MDD) is a widespread mental health condition that for many is disabling. It has long been appreciated that MDD has genetic as well as environmental influences.

2 Nov 2023

New mechanism discovered for aspirin's cancer-fighting properties

LMU researchers have identified a signaling pathway by which aspirin can inhibit colorectal cancer.

2 Nov 2023

Study uncovers how sex differences emerge and evolve in animals

Researchers at the Francis Crick Institute and Heidelberg University in Germany have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

2 Nov 2023